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Disease · MONDO_0043839

Comparisons in its trials18

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Onabotulinum Toxin Type-A vs Placebo: deaths from any cause0 of 230 of 2548NCT01309802Trial comparisons
Onabotulinum Toxin Type-A vs Placebo: serious adverse events2 of 235 of 2548NCT01309802Trial comparisons
Riociguat vs Placebo: Proportion of Participants Who Experience Digital Ischemia Requiring Intravenous Prostacyclin or Digital Gangrene or Amputation During the Trial.0 of 91 of 817NCT02915835Trial comparisons
Riociguat vs Placebo: deaths from any cause0 of 90 of 817NCT02915835Trial comparisons
Riociguat vs Placebo: Proportion of Participants Who Develop Osteomyelitis During The Trial0 of 90 of 817NCT02915835Trial comparisons
Riociguat vs Placebo: serious adverse events3 of 91 of 817NCT02915835Trial comparisons
Riociguat vs Placebo: Proportion of Participants Who Develop Pressure Ulcers at Proximal Interphalangeal (PIP) Location Over the Course of the Double-blind Period.1 of 82 of 816NCT02915835Trial comparisons
Riociguat vs Placebo: Proportion of Participants With New Active and Indeterminate DU(s) Over the Course of the Double-blind Period3 of 84 of 816NCT02915835Trial comparisons
Riociguat vs Placebo: Proportion of Participants With Healing of Their Cardinal DU by Week 164 of 86 of 816NCT02915835Trial comparisons
Riociguat vs Placebo: Proportion of Participants Who Develop Pressure Ulcers at Distal Interphalangeal (DIP) Location Over the Course of the Double-blind Period.0 of 81 of 816NCT02915835Trial comparisons
Riociguat vs Placebo: Proportion of Participants With Healing of All Pressure Ulcers at the Elbows Over the Course of the Double-blind Period.0 of 80 of 816NCT02915835Trial comparisons
Riociguat vs Placebo: Proportion of Participants With Healing of All DUs at Baseline by Week 163 of 83 of 816NCT02915835Trial comparisons
Riociguat vs Placebo: Proportion of Participants With Healing of All Pressure Ulcers at the Proximal Interphalangeal (PIP) Over the Course of the Double-blind Period.1 of 80 of 816NCT02915835Trial comparisons
Riociguat vs Placebo: Proportion of Participants With no DUs at Week 162 of 82 of 816NCT02915835Trial comparisons
Riociguat vs Placebo: Proportion of Participants With Healing of All Pressure Ulcers at the Metacarpophalangeal (MCPs) Over the Course of the Double-blind Period.0 of 80 of 816NCT02915835Trial comparisons
Riociguat vs Placebo: Proportion of Participants Who Develop Pressure Ulcers at Metacarpophalangeal (MCPs) Location Over the Course of the Double-blind Period.0 of 80 of 816NCT02915835Trial comparisons
Riociguat vs Placebo: Proportion of Participants Who Develop Pressure Ulcers at the Elbows Over the Course of the Double-blind Period.0 of 80 of 816NCT02915835Trial comparisons
Riociguat vs Placebo: Proportion of Participants With Healing of All Pressure Ulcers at the Distal Interphalangeal (DIP) Over the Course of the Double-blind Period.0 of 80 of 816NCT02915835Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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