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Disease · MONDO_0045057

Comparisons in its trials35

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Gabapentin vs Placebo: Incidence of Postoperative Delirium by Study Group84 of 35072 of 347697NCT00221338Trial comparisons
Gabapentin vs Placebo: deaths from any cause0 of 3501 of 347697NCT00221338Trial comparisons
Gabapentin vs Placebo: serious adverse events31 of 35044 of 347697NCT00221338Trial comparisons
Dexmedetomidine vs Propofol: Death at 90 Days81 of 21482 of 208422NCT01739933Trial comparisons
Dexmedetomidine vs Propofol: deaths from any cause89 of 21486 of 208422NCT01739933Trial comparisons
Dexmedetomidine vs Propofol: serious adverse events0 of 2140 of 208422NCT01739933Trial comparisons
Dexmedetomidine vs Control: deaths from any cause0 of 801 of 81161NCT02819141Trial comparisons
Dexmedetomidine vs Control: serious adverse events12 of 805 of 81161NCT02819141Trial comparisons
Suvorexant Arm vs Placebo Arm: deaths from any cause1 of 660 of 57123NCT05733286Trial comparisons
Suvorexant Arm vs Placebo Arm: serious adverse events9 of 669 of 57123NCT05733286Trial comparisons
Ramelteon vs Placebo: deaths from any cause3 of 594 of 61120NCT02691013Trial comparisons
Ramelteon vs Placebo: serious adverse events0 of 590 of 61120NCT02691013Trial comparisons
Ramelteon vs Placebo: Number of Participants With Delirium19 of 5922 of 58117NCT02691013Trial comparisons
Guanfacine vs Placebo: deaths from any cause9 of 5010 of 50100NCT04578886Trial comparisons
Guanfacine vs Placebo: serious adverse events0 of 500 of 50100NCT04578886Trial comparisons
Intervention Group (Lorazepam & Haloperidol) vs Control Group (Placebo & Haloperidol): deaths from any cause10 of 4710 of 4390NCT01949662Trial comparisons
Intervention Group (Lorazepam & Haloperidol) vs Control Group (Placebo & Haloperidol): Number of Participants With Richmond Agitation-Sedation Scale Score >=1 Within 8 hr8 of 2922 of 2958NCT01949662Trial comparisons
Intervention Group (Lorazepam & Haloperidol) vs Control Group (Placebo & Haloperidol): serious adverse events0 of 290 of 2958NCT01949662Trial comparisons
Infusion of Dexmedetomidine vs Standard of Care: Resolution of Delirium21 of 2514 of 2853NCT00351299Trial comparisons
Infusion of Dexmedetomidine vs Standard of Care: serious adverse events0 of 250 of 2853NCT00351299Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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