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Disease · MONDO_0056806

Comparisons in its trials19

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
PF-06439535 vs Bevacizumab-EU: Number of Participants With Laboratory Abnormalities (Without Regard to Baseline Abnormality)303 of 342304 of 348690NCT02364999Trial comparisons
MB02 (Bevacizumab Biosimilar Drug) vs EU-approved Avastin®: deaths from any cause23 of 31124 of 310621NCT03296163Trial comparisons
MB02 (Bevacizumab Biosimilar Drug) vs EU-approved Avastin®: serious adverse events58 of 31154 of 310621NCT03296163Trial comparisons
Chemotherapy (Carboplatin/ Cisplatin) + (Pemetrexed/ Gemcitabine) vs Atezolizumab: deaths from any cause211 of 287201 of 285572NCT02409342Trial comparisons
Chemotherapy (Carboplatin/ Cisplatin) + (Pemetrexed/ Gemcitabine) vs Atezolizumab: serious adverse events77 of 26397 of 286549NCT02409342Trial comparisons
Sintilimab vs Docetaxel: deaths from any cause108 of 144101 of 130274NCT03150875Trial comparisons
Sintilimab vs Docetaxel: serious adverse events56 of 14434 of 130274NCT03150875Trial comparisons
Crizotinib vs Chemotherapy: deaths from any cause62 of 10461 of 101205NCT01639001Trial comparisons
Crizotinib vs Chemotherapy: serious adverse events46 of 10413 of 101205NCT01639001Trial comparisons
Lenvatinib vs Lenvatinib Matched Placebo: serious adverse events46 of 8921 of 46135NCT01529112Trial comparisons
Arm 3 Boserolimab 30 mg Q3W + Pembrolizumab 200 mg Q3W + Pemetrexed + Carboplatin (NSCLC) vs Arm 4 Boserolimab 30 mg Q6W + Pembrolizumab 400 mg Q6W + Nab-paclitaxel (TNBC): Arm 3 and 4: Number of Participants Who Discontinued Study Treatment Due to an AE
2 of 106 of 4151NCT03396445Trial comparisons
Arm 3 Boserolimab 30 mg Q3W + Pembrolizumab 200 mg Q3W + Pemetrexed + Carboplatin (NSCLC) vs Arm 4 Boserolimab 30 mg Q6W + Pembrolizumab 400 mg Q6W + Nab-paclitaxel (TNBC): Arm 3 and 4: Number of Participants With One or More AEs
10 of 1041 of 4151NCT03396445Trial comparisons
Progression-free Survival Rate/KRAS Negative Group vs Progression-free Survival Rate/KRAS Mutant Group: Progression Free Survival Rate4 of 150 of 1530NCT02047344Trial comparisons
Arm A-Vinorelbine vs Arm B-Pemetrexed: serious adverse events4 of 82 of 1422NCT00545948Trial comparisons
8 mg/kg TRC105 + Bevacizumab + Paclitaxel/Carboplatin vs 10 mg/kg TRC105 + Bevacizumab + Paclitaxel/Carboplatin: Percent of Patients With Progression-free Survival (PFS) at 6 Months1 of 37 of 1013NCT03780010Trial comparisons
Atezolizumab vs Gemcitabine + Cisplatin/Carboplatin: deaths from any cause1 of 41 of 48NCT02409355Trial comparisons
Atezolizumab vs Gemcitabine + Cisplatin/Carboplatin: serious adverse events1 of 41 of 48NCT02409355Trial comparisons
Sapanisertib 3 mg QD vs Sapanisertib 2 mg BID: deaths from any cause1 of 40 of 37NCT05275673Trial comparisons
Sapanisertib 3 mg QD vs Sapanisertib 2 mg BID: serious adverse events1 of 41 of 37NCT05275673Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

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