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Disease · MONDO_0100135

Comparisons in its trials13

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Soticlestat vs Placebo: deaths from any cause1 of 730 of 71144NCT04940624Trial comparisons
Soticlestat vs Placebo: serious adverse events7 of 7310 of 71144NCT04940624Trial comparisons
TAK-935 vs Placebo: deaths from any cause0 of 710 of 70141NCT03650452Trial comparisons
TAK-935 vs Placebo: serious adverse events11 of 7113 of 70141NCT03650452Trial comparisons
Cohort 2: ZX008 0.5 mg/kg/Day vs Cohort 2: Matching Placebo: deaths from any cause0 of 430 of 4487NCT02926898Trial comparisons
Cohort 2: ZX008 0.5 mg/kg/Day vs Cohort 2: Matching Placebo: serious adverse events6 of 437 of 4487NCT02926898Trial comparisons
Ataluren vs Placebo: deaths from any cause0 of 150 of 1429NCT02758626Trial comparisons
Ataluren vs Placebo: serious adverse events7 of 151 of 1429NCT02758626Trial comparisons
Core Study: Lorcaserin vs Core Study: Placebo: Core Study: Number of Participants With Treatment-emergent Adverse Events (TEAEs)9 of 117 of 1021NCT04572243Trial comparisons
Tuberous Sclerosis Complex vs Dravet Syndrome: Number of Participants With Treatment-Emergent Adverse Events (TEAEs)2 of 21 of 13NCT04485104Trial comparisons
Tuberous Sclerosis Complex vs Dravet Syndrome: deaths from any cause0 of 20 of 13NCT04485104Trial comparisons
Tuberous Sclerosis Complex vs Dravet Syndrome: Number of Participants With Emergence of New Types of Seizures1 of 20 of 13NCT04485104Trial comparisons
Tuberous Sclerosis Complex vs Dravet Syndrome: serious adverse events2 of 20 of 13NCT04485104Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0100135/comparisons