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Disease · MONDO_0100342

Comparisons in its trials43

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Arm A: Ph 2 Radiation Therapy, TMZ and BMX-001 vs Arm B: Ph 2 Radiation Therapy and TMZ: Phase 2: Incidence of Treatment-Emergent Adverse Events [Safety and Tolerability]17 of 8013 of 80160NCT02655601Trial comparisons
Arm A: Ph 2 Radiation Therapy, TMZ and BMX-001 vs Arm B: Ph 2 Radiation Therapy and TMZ: Phase 2: Protection of Bone Marrow Against Chemotherapy-Induced Thrombocytopenia1 of 782 of 71149NCT02655601Trial comparisons
Phase 1 Dose Escalation vs Phase 2 Recurrent Malignant Gliomas and Nonprogressive Gbm: serious adverse events0 of 322 of 99131NCT00045110Trial comparisons
Lerapolturev vs Lerapolturev + Lomustine: Number of Participants With Objective Radiographic Response5 of 932 of 27120NCT02986178Trial comparisons
Lerapolturev vs Lerapolturev + Lomustine: Safety of Lerapolturev17 of 948 of 26120NCT02986178Trial comparisons
Bevacizumab Resistant Patients vs Bevacizumab Naive Patients: Number of Participants With Adverse Events44 of 4443 of 4387NCT00923117Trial comparisons
Bevacizumab Resistant Patients vs Bevacizumab Naive Patients: serious adverse events16 of 4413 of 4387NCT00923117Trial comparisons
Metronomic Therapy Cohort vs Dose-Dense Therapy Cohort: deaths from any cause0 of 431 of 4285NCT00200161Trial comparisons
Metronomic Therapy Cohort vs Dose-Dense Therapy Cohort: serious adverse events0 of 430 of 4285NCT00200161Trial comparisons
Enzastaurin + Bevacizumab (NEIAED) vs Enzastaurin + Bevacizumab (EIAED): serious adverse events24 of 684 of 1381NCT00586508Trial comparisons
Phase I (Erlotinib & Temsirolimus) vs Phase II (Erlotinib & Erlotinib): serious adverse events3 of 212 of 5980NCT00112736Trial comparisons
Cohorts 1: Surgical Subjects vs Cohorts 2: Non-surgical Subjects: deaths from any cause0 of 152 of 5065NCT01339052Trial comparisons
Cohorts 1: Surgical Subjects vs Cohorts 2: Non-surgical Subjects: serious adverse events5 of 1512 of 5065NCT01339052Trial comparisons
Glioblastoma vs Grade III Glioma: Patients With Tumors With Functional Alterations of the Mismatch Repair (MMR) System0 of 400 of 2060NCT00619112Trial comparisons
Glioblastoma vs Grade III Glioma: Patients Progressing 6 Months After Temozolomide is Voluntarily Discontinued4 of 404 of 2060NCT00619112Trial comparisons
Glioblastoma vs Grade III Glioma: Patients Progressing Within 6 Months After 6th Adjuvant Course of Temozolomide4 of 401 of 2060NCT00619112Trial comparisons
Glioblastoma vs Grade III Glioma: Patients Progressing After Two First-line Adjuvant Courses of Temozolomide3 of 400 of 2060NCT00619112Trial comparisons
Grade III vs Grade IV: Safety of Study Treatment Regimen9 of 3213 of 2759NCT00612430Trial comparisons
Grade III vs Grade IV: serious adverse events2 of 323 of 2759NCT00612430Trial comparisons
EIAED vs Non-EIAED: Number of Patients With Grade 3 or Greater, Treatment-related, Non-hematologic Toxicities27 of 2824 of 2856NCT00611325Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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