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Gene · 1645

Papers1,803

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
An Ex Vivo Model for the Onset of Human Labor.Reprod Sci202642778872PubTator, text miningPubMed
Integrative single-cell and genomic analysis reveals NMB as a driver of metastatic adaptation in esophageal squamous cell carcinoma via metabolic rewiring and immune evasion.Front Cell Dev Biol202642740929PubTator, text miningPubMed
Halogenated bisphenol A alternatives inhibit aldo-keto reductase 1C1 and induce metabolic alterations in human adipocytes.J Hazard Mater202642585961PubTator, text miningPubMed
Lipedema as a hormone-sensitive stromal disorder: a four-pathway translational framework.Front Cell Dev Biol202642558412PubTator, text miningPubMed
Reduction of secondary 3-keto bile acids by aldo-keto reductase 1C1 and 1C4.Drug Metab Dispos202642401153PubTator, text miningPubMed
AKR1C1 Promotes ADC Resistance by Altering Uptake and Export.Cancer Discov202642394431PubTator, text miningPubMed
Erratum: [Corrigendum] Wentilactone A induces cell apoptosis by targeting AKR1C1 gene via the IGF-1R/IRS1/PI3K/AKT/Nrf2/FLIP/Caspase-3 signaling pathway in small cell lung cancer.Oncol Lett202642383286PubTator, text miningPubMed
Opportunities and challenges of dihydrodiol dehydrogenase expression in hepatocellular carcinoma.Crit Rev Oncol Hematol202642379507PubTator, text miningPubMed
Rational design and structural insights of osthole-derived selective AKR1C3 inhibitors with cellular activity.Bioorg Chem202642335733PubTator, text miningPubMed
Multi-algorithm machine learning combined with in silico gene knockout reveals the diagnostic value and functional regulatory networks of ferroptosis-related genes in gastric cancer.Transl Cancer Res202642305491PubTator, text miningPubMed
Human aldo-keto reductases (AKR1C1-AKR1C3) increase the mutagenicity of environmental nitroarenes in the mammalian HPRT forward gene mutagenicity assay.Mutat Res Genet Toxicol Environ Mutagen202642264600PubTator, text miningPubMed
H4K8 lactylation-mediated ferroptosis defense drives EGFR-TKI resistance in lung adenocarcinoma.Apoptosis202642213229PubTator, text miningPubMed
Targeting AKR1C1 overcomes lenvatinib resistance in hepatocellular carcinoma through the STAT3-ABC transporters pathway.J Gastrointest Oncol202642169913PubTator, text miningPubMed
Transcriptional Activation of SKA3 by SOX9 Promotes the Malignant Progression of Laryngeal Squamous Cell Carcinoma by Regulating AKR1C1.J Biochem Mol Toxicol202642077186PubTator, text miningPubMed
Roles of AKR1C1 in Non-small Cell Lung Cancer.Front Biosci (Landmark Ed)202642052851PubTator, text miningPubMed
A meso-acyl-BODIPY-based fluorogenic probe for the selective monitoring of aldo-keto reductase 1C1 in living cells.Chem Commun (Camb)202641989397PubTator, text miningPubMed
Ferroptosis in Glioblastoma and Neuroblastoma: Molecular Mechanisms and Novel Therapeutic Strategies.Curr Issues Mol Biol202641899419PubTator, text miningPubMed
Causal relationship between genetically predicted Enzyme and Tinnitus risk: a two-sample bi-directional mendelian randomization study.Braz J Otorhinolaryngol202641895103PubTator, text miningPubMed
AKR1C1 expression is induced by hexavalent chromium exposure and lung squamous carcinoma development for mediating lipid metabolic dysregulation.Talanta202641880905PubTator, text miningPubMed
Osteosarcoma cells promote intracellular iron detoxification to mitigate GPX4-mediated ferroptosis.Cancer Gene Ther202641872463PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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