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Gene · 169355

Papers1,314

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A kynurenine immune-metabolic subtype of depression defined by childhood maltreatment and IDO2: Evidence from multi-omics profiling.Psychol Med202642803521PubTator, text miningPubMed
Pharmacological Modulation of the Tryptophan-kynurenine Pathway by the Intervention of Indoleamine 2,3-dioxygenase 2 (IDO2) and Kynureninase (KYNU) in Ovarian Cancer.Curr Med Chem202642803175PubTator, text miningPubMed
The kynurenine pathway in RNA virus infection: immunometabolic control of antiviral defense and viral persistence.Front Immunol202642769543PubTator, text miningPubMed
Phytochemical Modulation of the Kynurenine Pathway (KYNP) and Its Emerging Mechanistic Insights into Cancer Progression: A Systematic Review.Int J Mol Sci202642737416PubTator, text miningPubMed
Compensatory pathways in tryptophan metabolism and immune regulation following IDO inhibition.Mol Biol Rep202642730796PubTator, text miningPubMed
A Di-Rhamnolipid (Rha2-C10-C10) Inhibits Colorectal Cancer Motility and Immune Evasion Through AKT-Associated Signaling and PD-L1 Regulation.Biofactors202642420774PubTator, text miningPubMed
Astilbin ameliorates hyperuricemia-associated renal injury in geese with gut-linked kynurenic acid immunometabolic remodeling.Int Immunopharmacol202642320251PubTator, text miningPubMed
MO-IPS suppresses acute myeloid leukemia through metabolic reprogramming and synergizes with anti-PD-1 immunotherapy.Funct Integr Genomics202642307804PubTator, text miningPubMed
Synergistic immunomodulatory combinations induce robust human tolerogenic dendritic cells for antigen-specific regulatory T cell generation.J Pharmacol Exp Ther202642184694PubTator, text miningPubMed
EHR Sampling Interval Bias Detection and Burden of Blood Pressure Excursions: Implications for Clinical Decision Support and Model Validity in Pediatric ECMO.Information (Basel)202642039933PubTator, text miningPubMed
Nexus of IDO1/Kynurenine Pathway to T-Cell Exhaustion: Hypoxia-Induced Tryptophan Metabolism in Glioblastoma.Metabolites202641893336PubTator, text miningPubMed
Urinary Tryptophan-Kynurenine Pathway Profiling in Bulgarian Children with Autism Spectrum Disorder (ASD): Neopterin Co-Varies with Kynurenine and Quinolinic Acid.Metabolites202641893320PubTator, text miningPubMed
Integrated metabolomic and transcriptomic analysis reveals novel plasma biomarkers and metabolic pathway dysregulation in latent tuberculosis infection.Microbiol Spectr202641891697PubTator, text miningPubMed
Discovery of triazole analogues as selective IDO1 inhibitors: Dual mechanistic effects on kynurenine pathway suppression and apoptosis in cancer cells.Bioorg Chem202641856068PubTator, text miningPubMed
Artemether and Euphorbia factor L9 suppress kynurenine production through distinct effects on tryptophan metabolism.Biochem J202641823303PubTator, text miningPubMed
Differences in the expression profiles of m6A-related genes and the prognostic role in immunotherapy for lung adenocarcinoma patients.Front Oncol202641809822PubTator, text miningPubMed
Human IDO2 exhibits unique binding affinities distinct to those of human IDO1.FEBS J202641804238PubTator, text miningPubMed
Genebody specific epigenomic reprogramming of transcriptome promotes immune evasion in oropharyngeal cancer patients in North-Eastern India.Clin Epigenetics202641796351PubTator, text miningPubMed
The Gut Microbiota-Tryptophan-Brain Axis in Autism Spectrum Disorder: A New Frontier for Probiotic Intervention.Microorganisms202641753599PubTator, text miningPubMed
Modulation of the Kynurenine Pathway: A New Approach for Treating Neurodegeneration.Life (Basel)202641752903PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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