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FNDC5: fibronectin type III domain containing 5
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Gene · 252995

Papers4,118

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

121 to 140 of 4,118

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TitleJournalYearPMIDFound bySource
Association between vitamin D status and circulating myokines (irisin, myostatin, and myonectin) in children: A cross-sectional study.PLoS One202642102092PubTator, text miningPubMed
Myokines in cancer: bridging molecular mechanisms to biomarker discovery and therapeutic innovation.Front Oncol202642094205PubTator, text miningPubMed
Effects of Resistance Exercise and Whey Protein Supplementation on Irisin Levels in Patients with MASLD Under a Calorie-Restricted Diet.Nutrients202642075090PubTator, text miningPubMed
In Silico Analyses Suggest That Exercise-Induced Irisin-Mediated Neuroprotection Supports Non-Pharmacological Preventive Strategies for Alzheimer's Disease in Public Health.Int J Environ Res Public Health202642074388PubTator, text miningPubMed
Correction: Tang et al. Treadmill Exercise Alleviates Cognition Disorder by Activating the FNDC5: Dual Role of Integrin αV/β5 in Parkinson's Disease. Int. J. Mol. Sci. 2023, 24, 7830.Int J Mol Sci202642074348PubTator, text miningPubMed
Metabolic Myokines and Adipokines in the Follicular Microenvironment: Implications for Oocyte Competence and IVF Outcomes.Int J Mol Sci202642073988PubTator, text miningPubMed
Effects of Two Different Training Programs on Cardiometabolic Health, Body Composition and Irisin in Middle Age Obese Males: A Pilot Study.Life (Basel)202642073466PubTator, text miningPubMed
Irisin supports ST2+ Treg cells.Nat Immunol202642062508PubTator, text miningPubMed
The potential clinical significance of immunomodulation of immune and inflammatory responses involving selected adipokines in patients with ovarian cancer - preliminary studies.Front Oncol202642057825PubTator, text miningPubMed
Effect of irisin on miRNA-associated changes in the PGC-1α/FNDC5/BDNF Axis in an in vitro model of MPP⁺-induced Parkinson's disease.Mol Biol Rep202642053899PubTator, text miningPubMed
Impact of mechanical unloading on the irisin precursor, FNDC5, in skeletal muscle of sheep as a large animal experimental model.JBMR Plus202642052354PubTator, text miningPubMed
The Role of Irisin and Physical Activity in Breast Cancer.In Vivo202642049429PubTator, text miningPubMed
FNDC4 and FNDC5 Attenuate SARS-CoV-2 S1-Induced Inflammatory Responses in Human Adipose Tissue.Eur J Clin Invest202642047312PubTator, text miningPubMed
[The effect of physiotherapy treatments on the immune system].Orv Hetil202642035409PubTator, text miningPubMed
Sex-specific changes in metabolic and musculoskeletal biomarkers after acute resistance exercise in healthy young adults.Appl Physiol Nutr Metab202642033358PubTator, text miningPubMed
The Myokine Irisin Represents an Indirect Pathway Linking Exercise to Hippocampal Subfields Relevant to Alzheimer's Disease and Neurogenesis.Aging Cell202642033046PubTator, text miningPubMed
Protective effects of irisin in sarcopenia: a promising treatment.J Orthop Translat202642016713PubTator, text miningPubMed
Bridging exercise biology and immunometabolism: A novel irisin pathway toward next-generation metabolic and neurodegenerative therapies.Metabol Open202642004824PubTator, text miningPubMed
Mechanosensitive Piezo1/Osteocalcin/Irisin Axis Protects Against Disuse-Induced Muscle Atrophy.Adv Sci (Weinh)202641995090PubTator, text miningPubMed
The crossroads between osteosarcopenia and intrinsic capacity-a narrative review.J Gerontol A Biol Sci Med Sci202641992814PubTator, text miningPubMed

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  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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