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INSIG1: insulin induced gene 1
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Gene · 3638

Papers1,445

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 1,445

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TitleJournalYearPMIDFound bySource
Engineering Stable Lentiviral Vector Producer Cells Improves LVV Production.Biotechnol Bioeng202642478279PubTator, text miningPubMed
The regulatory role of INSIG1 in testicular Sertoli cells in boars.Theriogenology202642468502PubTator, text miningPubMed
Targeting hepatic cholesterol sensing to tackle metabolic dysfunction-associated steatohepatitis.J Clin Invest202642454495PubTator, text miningPubMed
BMI-dependent methylation and clinical signatures in North Indian women with PCOS.Indian J Med Res202642397831PubTator, text miningPubMed
Macrophage INSIG1 deficiency drives psoriasiform dermatitis via the SREBP2-STAT1 axis.Nat Commun202642393041PubTator, text miningPubMed
Single-cell transcriptomics of leukocyte-enriched human milk reveals a highly diverse and adapted myeloid compartment.PLoS One202642113855PubTator, text miningPubMed
Addressing Older Adults' Sexual Health Needs in Regional Primary Care: A Qualitative Study of Barriers and Enablers.Aust J Rural Health202641928420PubTator, text miningPubMed
Circular RNAs in cancer: Its biogenesis, functions, relationships with cancer progression, applications in immunotherapy and biomarker potentials.Cancer Immunol Immunother202641915211PubTator, text miningPubMed
An EV-Guided Multi-Compartment Proof-of-Concept Framework for Biomarker Prioritization in Cholangiocarcinoma.Med Sci (Basel)202641892837PubTator, text miningPubMed
Vitamin B2 metabolism promotes FSP1 stability to prevent ferroptosis.Nat Struct Mol Biol202641826758PubTator, text miningPubMed
Exosomal non-coding RNAs in autoimmune diseases: molecular mechanisms and potential applications.Front Immunol202641798919PubTator, text miningPubMed
The compound LY295427 antagonizes 25-hydroxycholesterol through binding to INSIG.J Lipid Res202641796682PubTator, text miningPubMed
Integrative multi-omics analysis reveals cellular and molecular insights into gestational diabetes mellitus.Front Mol Biosci202641788625PubTator, text miningPubMed
Morpholine as a privileged scaffold for neurodegenerative disease therapeutics.RSC Adv202641788372PubTator, text miningPubMed
Expression Profile of Metabotropic Glutamate Receptors in Lung Adenocarcinoma: GRM5 and Validation of Its Targeting Drug Cinchonine.Int J Mol Sci202641751933PubTator, text miningPubMed
Colorectal cancer-derived extracellular vesicles: at the crossroads of the tumor microenvironment and gut microbiota.Front Immunol202641727493PubTator, text miningPubMed
Energy-sensing molecule RORγ regulates cholesterol metabolism and immune signaling in diabetic kidney disease and aging.Nat Commun202641708627PubTator, text miningPubMed
STAT1 signaling controls cholesterol metabolism in epithelial cells and RSV-induced syncytia formation.Npj Viruses202641699197PubTator, text miningPubMed
Aberrantly expressed long noncoding RNAs in adipose-derived mesenchymal stem cells differentiation to nucleus pulposus-like cells.Sci Rep202641667574PubTator, text miningPubMed
KDM5B cooperates with CRL4B complex to promote the tumorigenesis of ER+ breast cancer via regulating cholesterol metabolism.Cell Death Dis202641654562PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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