Gene · 7150
Papers4,103
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
41 to 60 of 4,103
Download this page as JSON| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A Case Study on the Impact of Thermal Hydrolysis and Lactone Ring Opening of Linker-Payload on Drug-to-Antibody Ratio Determination in a Topoisomerase I Inhibitor-Based ADC. | Bioconjug Chem | 2026 | 42237689 | PubTator, text mining | PubMed |
| Thrombin-PAR1 signaling regulates Topoisomerase 1 activity to bridge inflammation and breast cancer progression. | Cancer Lett | 2026 | 42219057 | PubTator, text mining | PubMed |
| Neoadjuvant Sacituzumab Govitecan in Patients With Muscle-Invasive Bladder Cancer: Primary Results of the SURE-01 Trial. | J Clin Oncol | 2026 | 42218654 | PubTator, text mining | PubMed |
| Arginine methylation of human DNA topoisomerase I by PRMT5 facilitates DNA relaxation. | Nucleic Acids Res | 2026 | 42216760 | PubTator, text mining | PubMed |
| Identification of a TOP3A genetic variant as a novel biomarker for sensitivity to doxorubicin. | Front Pharmacol | 2026 | 42212268 | PubTator, text mining | PubMed |
| Luteolin as a Multitarget Agent against Colorectal Cancer Explored Through Integrative Network Pharmacology, Molecular Docking, and Dynamics Simulations. | Curr Comput Aided Drug Des | 2026 | 42152250 | PubTator, text mining | PubMed |
| Spatiotemporal graph learning for detection and localization of external inflows in sustainable urban sewer systems. | Water Res | 2026 | 42150224 | PubTator, text mining | PubMed |
| Phosphorylation by CDK1 switches the function of the human SLX4 SAP domain from DNA binding to MUS81 binding. | Nucleic Acids Res | 2026 | 42130070 | PubTator, text mining | PubMed |
| A CHK1-mediated phosphorylation switch suppresses human Topoisomerase 1-associated genomic instability. | EMBO J | 2026 | 42129541 | PubTator, text mining | PubMed |
| Molecular Determinants of Response and Rational Drug Combinations for Antibody-Drug Conjugates (ADCs) with Topoisomerase I (TOP1) Inhibitor Payloads. | J Mol Biol | 2026 | 42092629 | PubTator, text mining | PubMed |
| PARP1 regulates the genomic ribonucleotide processing activity of TOP1 to prevent the formation of toxic TOP1-DNA adducts and the associated mutations. | bioRxiv | 2026 | 42079065 | PubTator, text mining | PubMed |
| A Moderate-Affinity Antibody-Drug Conjugate Targeting B7-H3 Exerts Potent Antitumor Efficacy. | Pharmaceuticals (Basel) | 2026 | 42075852 | PubTator, text mining | PubMed |
| Integrative Mapping of SNHG1 RNA-Chromatin Contacts onto the Cancer-Specific Super-Enhancer Landscape in HCT116 Colorectal Cancer Cells. | Int J Mol Sci | 2026 | 42074278 | PubTator, text mining | PubMed |
| Integrated Global Phosphoproteomic, Bioinformatic, and Machine Learning Analysis Reveals Regulatory Networks of TOP1, TOP2A, TOP2B, and C1orf35 in Hepatocellular Carcinoma (HCC). | Oncol Res | 2026 | 42065042 | PubTator, text mining | PubMed |
| The Influence of TDP1 Inhibitor Usnic Acid Derivative OL9-116 on the Effects of Topotecan in Human Cells. | Curr Issues Mol Biol | 2026 | 42042088 | PubTator, text mining | PubMed |
| KCTD10 as a selective cancer dependency from transcription-replication conflicts (TRCs). | Ageing Cancer Res Treat | 2026 | 42037670 | PubTator, text mining | PubMed |
| Overcoming ADC resistance in advanced colorectal cancer by dual targeting of TROP2 and PERK to suppress Wnt/β-catenin signaling. | Cell Rep Med | 2026 | 42030933 | PubTator, text mining | PubMed |
| Deciphering the dual effects of transcription on DNA replication elongation by replication-associated Micro-C. | Mol Cell | 2026 | 42019499 | PubTator, text mining | PubMed |
| Activation of an adaptive antitumor immune response by the polymeric fluoropyrimidine CF10 involves TS/Top1 dual targeting. | Biomed Pharmacother | 2026 | 42019467 | PubTator, text mining | PubMed |
| Design, Synthesis and Biological Evaluation of 6H-Benzimidazo[1',2':1,2]pyrido[3,4-b]indole Derivatives as TDP1 Inhibitors: Potent Synergistic Agents with Topotecan against Cervical Cancer. | J Med Chem | 2026 | 42012226 | PubTator, text mining | PubMed |
gene-search-2026-11-11-0.2.0
Sources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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