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Gene · 9123

Papers3,520

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Monocarboxylate transporters in physiology and cancer: from fundamentals to clinical translation.Physiol Rev202742809741PubTator, text miningPubMed
Lactate as a Potential Exercise-Induced Signaling Molecule: Implications for Immunometabolic Adaptation Following HIIT.Muscles202642784047PubTator, text miningPubMed
Glut1 and MCT4 cooperatively promote ccRCC cell proliferation and are associated with glycolytic reprogramming and immune-related alterations.Biochem Biophys Res Commun202642732652PubTator, text miningPubMed
Involvement of Protein Kinase C Delta and Monocarboxylate Transporter 4 in the Development of Statin-Induced Cytotoxicity in a Rhabdomyosarcoma-Derived Cell Line.Biol Pharm Bull202642702544PubTator, text miningPubMed
Astrocyte-microglia lactate shuttle restrains microglial phenotypic transition during myelin phagocytosis in radiation-induced brain injury.Neurooncol Adv202642699581PubTator, text miningPubMed
My Love Story With HIFs in the Disc: A Journey to the Humboldt Research Award.JOR Spine202642694344PubTator, text miningPubMed
Plant-Based α-Linolenic Acid as a Superior Nutraceutical to Modulates Apoptosis, Hypoxic Signaling, and Lipid Metabolic Pathway in Breast Cancer: A Comparative Preclinical Study.Mol Nutr Food Res202642671985PubTator, text miningPubMed
Targeted Lactic Acid Regulation via Engineered Exosomes for Synergistic Metabolic and Photodynamic Tumor Therapy.Adv Healthc Mater202642665938PubTator, text miningPubMed
Lactate as a Master Regulator of Immune Suppression: From Metabolic Waste to Epigenetic Checkpoint in Colorectal Cancer.Int J Mol Sci202642653493PubTator, text miningPubMed
High-spatiotemporal resolution deuterium metabolic imaging enables in vivo phenotyping of intra- and intertumoral heterogeneity.Sci Adv202642627885PubTator, text miningPubMed
Lactate metabolism in the metastatic cascade: Microenvironmental remodeling, epigenetic reprogramming, and therapeutic strategies.Crit Rev Oncol Hematol202642595196PubTator, text miningPubMed
SLC16A3 links tumor metabolism to therapeutic opportunities in hepatocellular carcinoma.Transl Cancer Res202642591625PubTator, text miningPubMed
Construction of lactate-myeloid-related prognostic risk model and prediction of immune-excluded microenvironment in gastric cancer via integrated scRNA-Seq and bulk RNA-Seq.Transl Cancer Res202642591570PubTator, text miningPubMed
Methylglyoxal Attenuates Mycobacterium avium subspecies paratuberculosis (MAP)-Induced Pro-Inflammatory Macrophage Programming Associated with NRF-2 Antioxidant Responses and Reduced MCT4/Lactate-Linked Inflammatory Markers.
Int J Mol Sci202642589594PubTator, text miningPubMed
Ozone Hydrotherapy Improves Seborrheic Dermatitis by Regulating Scalp Microbiome and Mitochondrial Lactate Shuttle in Keratinocytes.J Infect Dis202642586552PubTator, text miningPubMed
Mitochondrial bioenergetic remodeling underlies fingolimod-induced immunometabolic adaptation in multiple sclerosis.Biomed Pharmacother202642570637PubTator, text miningPubMed
Cyanoacrylic acid ester-substituted 2- and 7-azaindoles mediate potency, efficacy, and specificity toward the monocarboxylate transporters (MCTs) 1 and 4.Eur J Med Chem202642551131PubTator, text miningPubMed
MCT4-mediated lactate efflux promotes STING-dependent dendritic cell antitumor immunity.Cell Rep202642541722PubTator, text miningPubMed
MCT4-Mediated Metabolic Reprogramming in Tumor-Associated Macrophages Promotes Hepatocellular Carcinoma Progression.Cell J202642538868PubTator, text miningPubMed
Astrocytic lactate shuttle disruption and the energy-starved lysosome in Alzheimer's disease.Res Sq202642523500PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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