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TOX: thymocyte selection associated high mobility group box
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Gene · 9760

Papers2,030

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 2,030

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TitleJournalYearPMIDFound bySource
Advanced-stage cutaneous T-cell lymphomas show distinct immune profiles in erythroderma vs. tumor lesions.J Dermatol Sci202642810908PubTator, text miningPubMed
TIGIT regulates CD8+T cell exhaustion via the PI3K/AKT-FOXO1-TOX axis in extrahepatic cholangiocarcinoma.Clin Immunol202642810560PubTator, text miningPubMed
T cell exhaustion in sepsis: mechanisms, biomarkers, and immune-reversal strategies.Front Immunol202642756179PubTator, text miningPubMed
Checkpoint-enriched T cells with retained effector-associated features are associated with disease activity in systemic lupus erythematosus.Front Immunol202642746266PubTator, text miningPubMed
Immune dysregulation and stem-like CD8+ T cell enrichment in type 1 diabetes pancreatic lymph nodes.J Clin Invest202642741944PubTator, text miningPubMed
ANKRD11 deficiency reprograms CD8+ T cell differentiation to enhance immunity in chronic infection and cancer.Nat Immunol202642728401PubTator, text miningPubMed
Disulfidptosis as an immunometabolic rheostat in gastrointestinal cancers: tuning the balance between T Cell exhaustion and immunogenic cell death.Front Cell Dev Biol202642724329PubTator, text miningPubMed
High HBV antigen levels drive loss of vaccine-induced CD8+ T-cell function in carrier mice over time.JHEP Rep202642722105PubTator, text miningPubMed
Corrigendum to 'TOX promotes the exhaustion of antitumor CD8+ T cells by preventing PD1 degradation in hepatocellular carcinoma' [J hepatol (2019) 71(4):731-741; doi: 10.1016/j.jhep.2019.05.015].J Hepatol202642711201PubTator, text miningPubMed
Hypoxia induces cytotoxicity and suppresses cytokine production by CD8□ T cells in cutaneous leishmaniasis.bioRxiv202642620055PubTator, text miningPubMed
Liver reprogramming toward hepatocellular carcinoma following hepatitis C sustained virologic response: a narrative review.Transl Gastroenterol Hepatol202642592470PubTator, text miningPubMed
H2AFY2 Suppresses Exhaustion and Enhances Antitumor Activity of CAR T Cells through Transcriptional and Epigenetic Modifications.Cancer Immunol Res202642578983PubTator, text miningPubMed
Characterizing and mitigating cross-library PCR chimeras in Perturb-seq using Perturb-Audit.Blood Sci202642578098PubTator, text miningPubMed
Targeting T-cell exhaustion and tumour immune evasion: a review of emerging strategies.Pathol Res Pract202642561529PubTator, text miningPubMed
Tumor-distal mediastinal lymph nodes harbor tumor-related progenitor exhausted T cells in lung cancer after neoadjuvant chemoimmunotherapy.Cell Rep Med202642546697PubTator, text miningPubMed
Spatial transcriptomics reveals an SPP1-centered immune-fibrotic axis associated with fibrosis-related tissue remodeling in IgG4-related disease.Front Immunol202642539786PubTator, text miningPubMed
Divergent cytotoxic and inflammatory functions of intratumoral Vδ2+ γδ T cells in renal cell carcinoma.Front Immunol202642539629PubTator, text miningPubMed
Association of Th2-like inflammation with Tfh/Tph-germinal center immune programmes in submandibular gland lesions of IgG4-related disease.Rheumatology (Oxford)202642538826PubTator, text miningPubMed
Targeting the fate of exhausted CD8+ T cells.Trends Immunol202642538164PubTator, text miningPubMed
Enhanced BCMA Antigen Density Increases Trogocytosis and Attenuates CAR T cell Function.bioRxiv202642523297PubTator, text miningPubMed

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  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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