Paper10074150
The retinoblastoma protein alters the phosphorylation state of polyomavirus large T antigen in murine cell extracts and inhibits polyomavirus origin DNA replication.
Reynisdóttir I and 3 others. J Virol, 1999. Cited by 6 papers, by iCite.
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ConductScience Library. The retinoblastoma protein alters the phosphorylation state of polyomavirus large T antigen in murine cell extracts and inhibits polyomavirus origin DNA replication. Papers, record 10074150. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/10074150
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- The retinoblastoma protein alters the phosphorylation state of polyomavirus large T antigen in murine cell extracts and inhibits polyomavirus origin DNA replication.
- PubMed
Topics12
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Antigens, Viral, Tumor | Major topic |
| Polyomavirus | Major topic |
| Retinoblastoma Protein | Major topic |
| Virus Replication | Major topic |
| Animals | |
| Cell Line | |
| Cell-Free System | |
| DNA Replication | |
| DNA, Viral | |
| Mice | |
| Mutation | |
| Phosphorylation |
Source PubMed
Grants1
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
| Grant, as the record writes it | Agency | Country | NIH project | Stated by |
|---|---|---|---|---|
| CA26905 | NCI NIH HHS | United States | R01CA026905 | PubMed and NIH |
Source NIH RePORTER
References88
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 1,648,101 | DNA helicase and duplex DNA fragment unwinding activities of polyoma and simian virus 40 large T antigen display similarities and differences. | J Biol Chem | 1991 | https://conductscience.org/library/papers/1648101 | PubMed |
| 2 | 8,392,624 | Mutation of the cyclin-dependent kinase phosphorylation site in simian virus 40 (SV40) large T antigen specifically blocks SV40 origin DNA unwinding. | J Virol | 1993 | https://conductscience.org/library/papers/8392624 | PubMed |
| 3 | 9,032,319 | Adding an Rb-binding site to an N-terminally truncated simian virus 40 T antigen restores growth to high cell density, and the T common region in trans provides anchorage-independent growth and rapid growth in low serum concentrations. | J Virol | 1997 | https://conductscience.org/library/papers/9032319 | PubMed |
| 4 | 8,139,575 | A unique subpopulation of murine DNA polymerase alpha/primase specifically interacts with polyomavirus T antigen and stimulates DNA replication. | Mol Cell Biol | 1994 | https://conductscience.org/library/papers/8139575 | PubMed |
| 5 | 212,199 | Characterization of T antigens in polyoma-infected and transformed cells. | Cell | 1978 | https://conductscience.org/library/papers/212199 | PubMed |
| 6 | 9,395,244 | Phosphorylated retinoblastoma protein stimulates DNA polymerase alpha. | Oncogene | 1997 | https://conductscience.org/library/papers/9395244 | PubMed |
| 7 | 3,018,726 | Species-specific in vitro synthesis of DNA containing the polyoma virus origin of replication. | Proc Natl Acad Sci U S A | 1986 | https://conductscience.org/library/papers/3018726 | PubMed |
| 8 | 8,411,381 | The replication functions of polyomavirus large tumor antigen are regulated by phosphorylation. | J Virol | 1993 | https://conductscience.org/library/papers/8411381 | PubMed |
| 9 | 2,839,300 | SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene. | Cell | 1988 | https://conductscience.org/library/papers/2839300 | PubMed |
| 10 | 8,087,839 | Smart machines at the DNA replication fork. | Cell | 1994 | https://conductscience.org/library/papers/8087839 | PubMed |
| 11 | 9,447,971 | Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes. | Mol Cell Biol | 1998 | https://conductscience.org/library/papers/9447971 | PubMed |
| 12 | 8,223,465 | The role of the 70 kDa subunit of human DNA polymerase alpha in DNA replication. | EMBO J | 1993 | https://conductscience.org/library/papers/8223465 | PubMed |
| 13 | 9,365,528 | Role of the Rb/E2F pathway in cell growth control. | J Cell Physiol | 1997 | https://conductscience.org/library/papers/9365528 | PubMed |
| 14 | 8,648,692 | Genetic analysis of polyomavirus large T nuclear localization: nuclear localization is required for productive association with pRb family members. | J Virol | 1996 | https://conductscience.org/library/papers/8648692 | PubMed |
| 15 | 7,596,441 | Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases. | Nature | 1995 | https://conductscience.org/library/papers/7596441 | PubMed |
| 16 | 2,824,994 | DNA sequence requirements for replication of polyomavirus DNA in vivo and in vitro. | Mol Cell Biol | 1987 | https://conductscience.org/library/papers/2824994 | PubMed |
| 17 | 8,126,000 | Initiation of DNA replication by simian virus 40 T antigen is inhibited by the p107 protein. | J Biol Chem | 1994 | https://conductscience.org/library/papers/8126000 | PubMed |
| 18 | 9,261,366 | Cyclin-dependent kinase regulation of the replication functions of polyomavirus large T antigen. | J Virol | 1997 | https://conductscience.org/library/papers/9261366 | PubMed |
| 19 | 9,417,859 | The retinoblastoma protein pathway in cell cycle control and cancer. | Exp Cell Res | 1997 | https://conductscience.org/library/papers/9417859 | PubMed |
| 20 | 9,694,794 | Inhibition of DNA synthesis by RB: effects on G1/S transition and S-phase progression. | Genes Dev | 1998 | https://conductscience.org/library/papers/9694794 | PubMed |
Cited by6
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 6 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 12,915,577 | Cell cycle regulation by Kaposi's sarcoma-associated herpesvirus K-bZIP: direct interaction with cyclin-CDK2 and induction of G1 growth arrest. | J Virol | 2003 | https://conductscience.org/library/papers/12915577 | PubMed |
| 12,414,923 | Inhibition of polyomavirus ori-dependent DNA replication by mSin3B. | J Virol | 2002 | https://conductscience.org/library/papers/12414923 | PubMed |
| 11,773,384 | The cyclin-dependent kinase inhibitor roscovitine inhibits the transactivating activity and alters the posttranslational modification of herpes simplex virus type 1 ICP0. | J Virol | 2002 | https://conductscience.org/library/papers/11773384 | PubMed |
| 11,507,202 | Amino acids 257 to 288 of mouse p48 control the cooperation of polyomavirus large T antigen, replication protein A, and DNA polymerase alpha-primase to synthesize DNA in vitro. | J Virol | 2001 | https://conductscience.org/library/papers/11507202 | PubMed |
| 11,160,673 | Different regions of primase subunit p48 control mouse polyomavirus and simian virus 40 DNA replication in vitro. | J Virol | 2001 | https://conductscience.org/library/papers/11160673 | PubMed |
| 10,880,461 | A geminivirus replication protein interacts with the retinoblastoma protein through a novel domain to determine symptoms and tissue specificity of infection in plants. | EMBO J | 2000 | https://conductscience.org/library/papers/10880461 | PubMed |
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- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
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- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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