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Paper1061069

Lambda repressor turns off transcription of its own gene.

Meyer BJ and 2 others. Proc Natl Acad Sci U S A, 1975. Cited by 143 papers, by iCite.

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ConductScience Library. Lambda repressor turns off transcription of its own gene. Papers, record 1061069. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/1061069

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Lambda repressor turns off transcription of its own gene.
PubMed
Journal
Proc Natl Acad Sci U S A
PubMed
Year
1975
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
143
iCite
Relative citation ratio, by iCite
3.18
iCite
Revised in PubMed
2019-05-01
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Meyer BJB J
2Kleid DGD G
3Ptashne MM

Source PubMed

Topics9

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
ColiphagesMajor topic
Suppression, GeneticMajor topic
Transcription, GeneticMajor topic
Base Sequence
Chromosome Mapping
DNA Restriction Enzymes
DNA, Viral
Haemophilus
Nucleic Acid Hybridization

Source PubMed

References20

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
15,279,042In vitro repression of RNA synthesis by purified lambda phage repressor.Nat New Biol1971https://conductscience.org/library/papers/5279042PubMed
24,545,512Control elements in the DNA of bacteriophage lambda.Cold Spring Harb Symp Quant Biol1974https://conductscience.org/library/papers/4545512PubMed
31,117,996Sequence of the PR promoter of phage lambda.Nature1975https://conductscience.org/library/papers/1117996PubMed
41,095,210Recognition sequences of repressor and polymerase in the operators of bacteriophage lambda.Cell1975https://conductscience.org/library/papers/1095210PubMed
54,583,306Genetic characterization of a prm- mutant of bacteriophage lambda.Virology1973https://conductscience.org/library/papers/4583306PubMed
64,586,104Structure of the lambda operators.Nature1973https://conductscience.org/library/papers/4586104PubMed
74,587,256The nucleotide sequence of the lactose messenger ribonucleic acid transcribed from the UV5 promoter mutant of Escherichia coli.Proc Natl Acad Sci U S A1973https://conductscience.org/library/papers/4587256PubMed
84,514,322Multiple repressor binding at the operators in bacteriophage lambda.Proc Natl Acad Sci U S A1973https://conductscience.org/library/papers/4514322PubMed
94,758,068Mutations in the right operator of bacteriophage lambda: evidence for operator-promoter interpenetration.J Mol Biol1973https://conductscience.org/library/papers/4758068PubMed
104,902,144Termination factor for RNA synthesis.Nature1969https://conductscience.org/library/papers/4902144PubMed
115,340,187Effect of ultraviolet irradiation on bacteriophage lambda immunity.J Mol Biol1967https://conductscience.org/library/papers/5340187PubMed
121,055,378Repression and autogenous stimulation in vitro by bacteriophage lambda repressor.Proc Natl Acad Sci U S A1975https://conductscience.org/library/papers/1055378PubMed
131,152,054Control of bacteriophage lambda repressor synthesis: regulation of the maintenance pathway of the cro and cI products.J Mol Biol1975https://conductscience.org/library/papers/1152054PubMed
141,174,504Chain length determination of small double- and single-stranded DNA molecules by polyacrylamide gel electrophoresis.Biochemistry1975https://conductscience.org/library/papers/1174504PubMed
155,244,737The operators controlled by the lambda phage repressor.Proc Natl Acad Sci U S A1968https://conductscience.org/library/papers/5244737PubMed
165,231,395Asymmetric distribution of the transcribing regions on the complementary strands of coliphage lambda DNA.Proc Natl Acad Sci U S A1967https://conductscience.org/library/papers/5231395PubMed
171,055,375Nucleotide sequence of the rightward operator of phage lambda.Proc Natl Acad Sci U S A1975https://conductscience.org/library/papers/1055375PubMed
184,546,908Separation and analysis of promoter sites in bacteriophage lambda DNA by specific endonucleases.J Mol Biol1974https://conductscience.org/library/papers/4546908PubMed
194,598,033Promoters are in the operators in phage lambda.Nature1974https://conductscience.org/library/papers/4598033PubMed
204,556,643RNA synthesis startpoints in bacteriophage lambda: are the promoter and operator transcribed?Nat New Biol1972https://conductscience.org/library/papers/4556643PubMed

Cited by54

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 143 citations.

PMIDTitleJournalYearIn PapersSource
41,603,749Molecular Mechanisms of Transcription Factors with Dual Activator and Repressor Functions.Mol Cell Biol2026https://conductscience.org/library/papers/41603749PubMed
40,310,292Insights on the regulation and function of the CRISPR/Cas transposition system located in the pathogenicity island VpaI-7 from Vibrio parahaemolyticus RIMD2210633.Infect Immun2025https://conductscience.org/library/papers/40310292PubMed
35,393,441A genetic toolkit and gene switches to limit Mycoplasma growth for biosafety applications.Nat Commun2022https://conductscience.org/library/papers/35393441PubMed
32,513,117Whole genome sequencing identifies an allele responsible for clear vs. turbid plaque morphology in a Mycobacteriophage.BMC Microbiol2020https://conductscience.org/library/papers/32513117PubMed
31,545,538Elements in the λ immunity region regulate phage development: beyond the 'Genetic Switch'.Mol Microbiol2019https://conductscience.org/library/papers/31545538PubMed
31,057,041Transcribe this way: Rap1 confers promoter directionality by repressing divergent transcription.Transcription2019https://conductscience.org/library/papers/31057041PubMed
30,376,434Sex and death: from cell fate specification to dynamic control of X-chromosome structure and gene expression.Mol Biol Cell2018https://conductscience.org/library/papers/30376434PubMed
27,670,714New Insights into the Phage Genetic Switch: Effects of Bacteriophage Lambda Operator Mutations on DNA Looping and Regulation of PR, PL, and PRM.J Mol Biol2016https://conductscience.org/library/papers/27670714PubMed
27,043,626Mechanisms that Determine the Differential Stability of Stx⁺ and Stx(-) Lysogens.Toxins (Basel)2016https://conductscience.org/library/papers/27043626PubMed
26,705,574Evidence that bacteriophage λ lysogens may induce in response to the proton motive force uncoupler CCCP.FEMS Microbiol Lett2016https://conductscience.org/library/papers/26705574PubMed
25,811,873Genome-based identification of active prophage regions by next generation sequencing in Bacillus licheniformis DSM13.PLoS One2015https://conductscience.org/library/papers/25811873PubMed
23,831,434Purification of bacteriophage lambda repressor.Protein Expr Purif2013https://conductscience.org/library/papers/23831434PubMed
21,873,207Multilevel autoregulation of λ repressor protein CI by DNA looping in vitro.Proc Natl Acad Sci U S A2011https://conductscience.org/library/papers/21873207PubMed
19,167,308Quantitative transcription factor binding kinetics at the single-molecule level.Biophys J2009https://conductscience.org/library/papers/19167308PubMed
16,592,779Preferential transcription of cloned maize chloroplast DNA sequences by maize chloroplast RNA polymerase.Proc Natl Acad Sci U S A1980https://conductscience.org/library/papers/16592779PubMed
16,068,162Regulatory functions of the lambda repressor reside in the amino-terminal domain.Nature1979https://conductscience.org/library/papers/16068162PubMed
7,027,256Mechanism of action of the lexA gene product.Proc Natl Acad Sci U S A1981https://conductscience.org/library/papers/7027256PubMed
7,027,255Purified lexA protein is a repressor of the recA and lexA genes.Proc Natl Acad Sci U S A1981https://conductscience.org/library/papers/7027255PubMed
6,994,102Autogenous control of Escherichia coli ribosomal protein L10 synthesis in vitro.Proc Natl Acad Sci U S A1980https://conductscience.org/library/papers/6994102PubMed
6,990,417The lexA gene product represses its own promoter.Proc Natl Acad Sci U S A1980https://conductscience.org/library/papers/6990417PubMed

See all 54 cited by

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn Genes
FEZF255,079PubTator's text mininghttps://conductscience.org/library/genes/55079

Source NCBI Gene

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

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  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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