Paper · 1069311

Rat sympathetic neurons and cardiac myocytes developing in microcultures: correlation of the fine structure of endings with neurotransmitter function in single neurons.

Landis SC. Proc Natl Acad Sci U S A, 1976. Cited by 159 papers, by iCite.

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ConductScience Library. Rat sympathetic neurons and cardiac myocytes developing in microcultures: correlation of the fine structure of endings with neurotransmitter function in single neurons. Papers, record 1069311. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/1069311

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Rat sympathetic neurons and cardiac myocytes developing in microcultures: correlation of the fine structure of endings with neurotransmitter function in single neurons.; PubMed
Journal: Proc Natl Acad Sci U S A; PubMed
Year: 1976; PubMed
Publication types: Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/1069311/; PubMed
DOI: https://doi.org/10.1073/pnas.73.11.4220; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC431393/; PubMed
The journal: https://conductscience.org/library/journal-index/7505876; PubMed
Citations, by iCite: 159; iCite
Relative citation ratio, by iCite: 4.05; iCite
Revised in PubMed: 2022-03-09; PubMed

Authors1

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Landis SC	S C

Source PubMed

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Acetylcholine	Major topic
Nerve Endings	Major topic
Neurons	Major topic
Norepinephrine	Major topic
Animals
Cells, Cultured
Ganglia, Autonomic
Heart
Microscopy, Electron
Myocardium
Rats
Synaptic Vesicles

Source PubMed

Grants0

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Trials0

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Comments and corrections0

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None in this release.

References23

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	14,263,902	[STUDIES ON THE ULTRASTRUCTURE OF THE SUPERIOR CERVICAL GANGLION IN RATS. I. NORMAL STRUCTURE].	Acta Anat (Basel)	1964	https://conductscience.org/library/papers/14263902	PubMed
2	14,131,855	THE FINE STRUCTURE OF THE ALBINO RABBIT IRIS WITH SPECIAL REFERENCE TO THE IDENTIFICATION OF ADRENERGIC AND CHOLINERGIC NERVES AND NERVE ENDINGS IN ITS INTRINSIC MUSCLES.	Am J Anat	1964	https://conductscience.org/library/papers/14131855	PubMed
3	186,792	Chemical transmission between rat sympathetic neurons and cardiac myocytes developing in microcultures: evidence for cholinergic, adrenergic, and dual-function neurons.	Proc Natl Acad Sci U S A	1976	https://conductscience.org/library/papers/186792	PubMed
4	7,384	Physiological and morphological studies on developing sympathetic neurons in dissociated cell culture.	Cold Spring Harb Symp Quant Biol	1976	https://conductscience.org/library/papers/7384	PubMed
5	4,117,873	Ultrastructure of the developing sympathetic nerve cell and the storage of catecholamines.	Brain Res	1972	https://conductscience.org/library/papers/4117873	PubMed
6	4,131,521	Fine structural identification of a reserpine-resistant norepinephrine store in adrenergic nerve terminals in guinea-pig atria.	J Pharmacol Exp Ther	1974	https://conductscience.org/library/papers/4131521	PubMed
7	4,163,997	Electron microscopic identification of autonomic nerve endings.	Nature	1966	https://conductscience.org/library/papers/4163997	PubMed
8	4,152,965	Morphological and cytochemical studies of synapses formed in culture between isolated rat superior cervical ganglion neurons.	J Comp Neurol	1974	https://conductscience.org/library/papers/4152965	PubMed
9	4,372,629	Evidence for cholinergic synapses between dissociated rat sympathetic neurons in cell culture.	Proc Natl Acad Sci U S A	1974	https://conductscience.org/library/papers/4372629	PubMed
10	183,125	Synaptic vesicle cytochemistry changes when cultured sympathetic neurones develop cholinergic interactions.	Nature	1976	https://conductscience.org/library/papers/183125	PubMed

1 to 10 of 23

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Cited by48

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 159 citations.

PMID	Title	Journal	Year	In Papers	Source
42,044,334	Physiological super-resolution in situ recording reveals kinetic changes of sympathetic norepinephrine release in heart failure.	Proc Natl Acad Sci U S A	2026	https://conductscience.org/library/papers/42044334	PubMed
41,034,673	Multimodal, device-based therapeutic targeting of the cardiovascular autonomic nervous system.	Nat Rev Cardiol	2026	https://conductscience.org/library/papers/41034673	PubMed
39,340,173	Neurocardiology: translational advancements and potential.	J Physiol	2025	https://conductscience.org/library/papers/39340173	PubMed
39,325,088	Optimization of an autaptic culture system for studying cholinergic synapses in sympathetic ganglia.	Pflugers Arch	2025	https://conductscience.org/library/papers/39325088	PubMed
38,778,747	Molecular and cellular neurocardiology in heart disease.	J Physiol	2025	https://conductscience.org/library/papers/38778747	PubMed
38,393,672	The relevance of the superior cervical ganglion for cardiac autonomic innervation in health and disease: a systematic review.	Clin Auton Res	2024	https://conductscience.org/library/papers/38393672	PubMed
37,796,292	A century of exercise physiology: concepts that ignited the study of human thermoregulation. Part 3: Heat and cold tolerance during exercise.	Eur J Appl Physiol	2024	https://conductscience.org/library/papers/37796292	PubMed
37,796,290	A century of exercise physiology: concepts that ignited the study of human thermoregulation. Part 4: evolution, thermal adaptation and unsupported theories of thermoregulation.	Eur J Appl Physiol	2024	https://conductscience.org/library/papers/37796290	PubMed
37,615,870	Complexins: Ubiquitously Expressed Presynaptic Regulators of SNARE-Mediated Synaptic Vesicle Fusion.	Adv Neurobiol	2023	https://conductscience.org/library/papers/37615870	PubMed
35,276,096	A cholinergic neuroskeletal interface promotes bone formation during postnatal growth and exercise.	Cell Stem Cell	2022	https://conductscience.org/library/papers/35276096	PubMed

1 to 10 of 48

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Data0

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Data dates

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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