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Paper · 10695620

Topical prostaglandin E2 protects isolated gastric mucosa against acidified taurocholate-, but not ethanol- or aspirin-induced injury.

Ranta-Knuuttila T and 2 others. Dig Dis Sci, 2000. Cited by 4 papers, by iCite.

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ConductScience Library. Topical prostaglandin E2 protects isolated gastric mucosa against acidified taurocholate-, but not ethanol- or aspirin-induced injury. Papers, record 10695620. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/10695620

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Topical prostaglandin E2 protects isolated gastric mucosa against acidified taurocholate-, but not ethanol- or aspirin-induced injury.
PubMed
Journal
Dig Dis Sci
PubMed
Year
2000
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
4
iCite
Relative citation ratio, by iCite
0.13
iCite
Revised in PubMed
2026-10-16
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Ranta-Knuuttila TT
2Mustonen HH
3Kivilaakso EE

Source PubMed

Topics9

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
16,16-Dimethylprostaglandin E2Major topic
AspirinMajor topic
EthanolMajor topic
Gastric MucosaMajor topic
Taurocholic AcidMajor topic
Administration, Topical
Animals
Hydrogen-Ion Concentration
Necturus maculosus

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References33

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
16,614,182Gastric and duodenal surface mucus gel thickness in rat: effects of prostaglandins and damaging agents.Am J Physiol1983https://conductscience.org/library/papers/6614182PubMed
23,257,451Effect of ethanol on frog gastric mucosa. Electrophysiologic and morphologic correlations.Gastroenterology1988https://conductscience.org/library/papers/3257451PubMed
33,183,340Protection of isolated rat gastric cells by prostaglandins from damage caused by ethanol. Preliminary report.J Clin Gastroenterol1988https://conductscience.org/library/papers/3183340PubMed
48,580,403Bile acid-induced depolarization of mitochondrial membrane potential preceding cell injury in cultured gastric mucosal cells.J Gastroenterol Hepatol1995https://conductscience.org/library/papers/8580403PubMed
52,945,748Early microcirculatory stasis in acute gastric mucosal injury in the rat and prevention by 16,16-dimethyl prostaglandin E2 or sodium thiosulfate.Gastroenterology1986https://conductscience.org/library/papers/2945748PubMed
62,753,325Prostaglandin prevents aspirin injury in the canine stomach under in vivo but not in vitro conditions.Gastroenterology1989https://conductscience.org/library/papers/2753325PubMed
73,040,097Prostaglandin E2 directly protects isolated rat gastric surface cell membranes against bile salts.Biochim Biophys Acta1987https://conductscience.org/library/papers/3040097PubMed
82,743,842Prostaglandin protection against hemorrhage-induced gastric stress ulceration in the rat.Dig Dis Sci1989https://conductscience.org/library/papers/2743842PubMed
9301,667Bile acids, the "barrier," and reflux-related clinical disorders of the gastric mucosa.Surgery1977https://conductscience.org/library/papers/301667PubMed
101,688,815Morphological effects of aspirin and prostaglandin on the canine gastric mucosal surface. Analysis with a phospholipid-selective cytochemical stain.Gastroenterology1990https://conductscience.org/library/papers/1688815PubMed

1 to 10 of 33

See all 33 references

Cited by2

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 4 citations.

PMIDTitleJournalYearIn PapersSource
14,627,353Effect of luminal ethanol on epithelial resistances and cell volume in isolated Necturus gastric mucosa.Dig Dis Sci2003https://conductscience.org/library/papers/14627353PubMed
12,395,910Effects of prostaglandin E2 on gastric irritant-induced apoptosis.Dig Dis Sci2002https://conductscience.org/library/papers/12395910PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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