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Paper10696099

Modulation of peristalsis by cannabinoid CB(1) ligands in the isolated guinea-pig ileum.

Izzo AA and 3 others. Br J Pharmacol, 2000. Cited by 50 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Modulation of peristalsis by cannabinoid CB(1) ligands in the isolated guinea-pig ileum. Papers, record 10696099. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/10696099

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Modulation of peristalsis by cannabinoid CB(1) ligands in the isolated guinea-pig ileum.
PubMed
Journal
Br J Pharmacol
PubMed
Year
2000
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
50
iCite
Relative citation ratio, by iCite
1.5
iCite
Revised in PubMed
2021-02-23
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Izzo AAA A
2Mascolo NN
3Tonini MM
4Capasso FF

Source PubMed

Topics20

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
IleumMajor topic
PeristalsisMajor topic
Receptors, DrugMajor topic
Animals
Benzoxazines
Camphanes
Cannabinoids
Compliance
Cyclohexanols
Guinea Pigs
In Vitro Techniques
Ligands
Male
Morpholines
Muscle Contraction
Naphthalenes
Piperidines
Pyrazoles
Receptors, Cannabinoid
Rimonabant

Source PubMed

References33

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
17,250,196Hyoscine-resistant peristalsis in guinea-pig ileum.Eur J Pharmacol1981https://conductscience.org/library/papers/7250196PubMed
29,863,666Comparison of cannabinoid binding sites in guinea-pig forebrain and small intestine.Br J Pharmacol1998https://conductscience.org/library/papers/9863666PubMed
31,335,057Aminoalkylindole analogs: cannabimimetic activity of a class of compounds structurally distinct from delta 9-tetrahydrocannabinol.J Pharmacol Exp Ther1992https://conductscience.org/library/papers/1335057PubMed
41,470,919Isolation and structure of a brain constituent that binds to the cannabinoid receptor.Science1992https://conductscience.org/library/papers/1470919PubMed
51,362,268Calcium entry blockade as a mechanism for chlordimeform-induced inhibition of motor activity in the isolated guinea-pig ileum.Pharmacol Toxicol1992https://conductscience.org/library/papers/1362268PubMed
66,249,985Opioids modulate periodicity rather than efficacy of peristaltic waves in the guinea pig ileum in vitro.Life Sci1980https://conductscience.org/library/papers/6249985PubMed
78,447,417Interplay of VIP and nitric oxide in regulation of the descending relaxation phase of peristalsis.Am J Physiol1993https://conductscience.org/library/papers/8447417PubMed
88,170,503Synergistic role of muscarinic acetylcholine and tachykinin NK-2 receptors in intestinal peristalsis.Naunyn Schmiedebergs Arch Pharmacol1994https://conductscience.org/library/papers/8170503PubMed
97,912,284Accommodation mediated by enteric inhibitory reflexes in the isolated guinea-pig small intestine.J Physiol1994https://conductscience.org/library/papers/7912284PubMed
107,932,234The role of enteric inhibitory motoneurons in peristalsis in the isolated guinea-pig small intestine.J Physiol1994https://conductscience.org/library/papers/7932234PubMed
117,776,817Biochemical and pharmacological characterisation of SR141716A, the first potent and selective brain cannabinoid receptor antagonist.Life Sci1995https://conductscience.org/library/papers/7776817PubMed
127,598,509Pharmacology of cannabinoid receptors.Annu Rev Pharmacol Toxicol1995https://conductscience.org/library/papers/7598509PubMed
137,605,349Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors.Biochem Pharmacol1995https://conductscience.org/library/papers/7605349PubMed
149,185,835Histamine H3 receptors do not modulate reflex-evoked peristaltic motility in the isolated guinea-pig ileum.Eur J Pharmacol1997https://conductscience.org/library/papers/9185835PubMed
159,283,688Inhibition by cannabinoid receptor agonists of acetylcholine release from the guinea-pig myenteric plexus.Br J Pharmacol1997https://conductscience.org/library/papers/9283688PubMed
169,295,166Distribution of anandamide amidohydrolase in rat tissues with special reference to small intestine.Biochim Biophys Acta1997https://conductscience.org/library/papers/9295166PubMed
179,313,943Effects of cannabinoid receptor ligands on electrophysiological properties of myenteric neurones of the guinea-pig ileum.Br J Pharmacol1997https://conductscience.org/library/papers/9313943PubMed
189,335,234Binding of the non-classical cannabinoid CP 55,940, and the diarylpyrazole AM251 to rodent brain cannabinoid receptors.Life Sci1997https://conductscience.org/library/papers/9335234PubMed
199,460,790Intrinsic primary afferent neurons of the intestine.Prog Neurobiol1998https://conductscience.org/library/papers/9460790PubMed
209,454,810SR 144528, the first potent and selective antagonist of the CB2 cannabinoid receptor.J Pharmacol Exp Ther1998https://conductscience.org/library/papers/9454810PubMed

See all 33 references

Cited by13

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 50 citations.

PMIDTitleJournalYearIn PapersSource
33,494,452Cannabinoid and Cannabinoid-Related Receptors in the Myenteric Plexus of the Porcine Ileum.Animals (Basel)2021https://conductscience.org/library/papers/33494452PubMed
28,990,365Endocannabinoid-related compounds in gastrointestinal diseases.J Cell Mol Med2018https://conductscience.org/library/papers/28990365PubMed
27,747,459Complementary Therapies in Inflammatory Bowel Diseases.Curr Gastroenterol Rep2016https://conductscience.org/library/papers/27747459PubMed
20,233,228Pharmacological characterization of cannabinoid receptor activity in the rat-isolated ileum myenteric plexus-longitudinal muscle preparation.Br J Pharmacol2010https://conductscience.org/library/papers/20233228PubMed
17,906,675Cannabinoid CB2 receptors in the gastrointestinal tract: a regulatory system in states of inflammation.Br J Pharmacol2008https://conductscience.org/library/papers/17906675PubMed
16,847,440Investigation on the relationship between cannabinoid CB1 and opioid receptors in gastrointestinal motility in mice.Br J Pharmacol2006https://conductscience.org/library/papers/16847440PubMed
16,783,406Tolerance to cannabinoid response on the myenteric plexus of guinea-pig ileum and human small intestinal strips.Br J Pharmacol2006https://conductscience.org/library/papers/16783406PubMed
16,634,642Mutations of CB1 T210 produce active and inactive receptor forms: correlations with ligand affinity, receptor stability, and cellular localization.Biochemistry2006https://conductscience.org/library/papers/16634642PubMed
12,055,136Influence of the CB(1) receptor antagonist, AM 251, on the regional haemodynamic effects of WIN-55212-2 or HU 210 in conscious rats.Br J Pharmacol2002https://conductscience.org/library/papers/12055136PubMed
11,588,110Cannabinoid CB1-receptor mediated regulation of gastrointestinal motility in mice in a model of intestinal inflammation.Br J Pharmacol2001https://conductscience.org/library/papers/11588110PubMed
11,358,910Cannabinoids and the gastrointestinal tract.Gut2001https://conductscience.org/library/papers/11358910PubMed
11,264,233Effect of vanilloid drugs on gastrointestinal transit in mice.Br J Pharmacol2001https://conductscience.org/library/papers/11264233PubMed
10,780,967Central and peripheral cannabinoid modulation of gastrointestinal transit in physiological states or during the diarrhoea induced by croton oil.Br J Pharmacol2000https://conductscience.org/library/papers/10780967PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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