Paper · 10696570

How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions.

Sapolsky RM and 2 others. Endocr Rev, 2000. Cited by 5,115 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions. Papers, record 10696570. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/10696570

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions.; PubMed
Journal: Endocr Rev; PubMed
Year: 2000; PubMed
Publication types: Journal Article, Research Support, U.S. Gov't, P.H.S., Review; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/10696570/; PubMed
DOI: https://doi.org/10.1210/edrv.21.1.0389; PubMed
The journal: https://conductscience.org/library/journal-index/8006258; PubMed
Citations, by iCite: 5,115; iCite
Relative citation ratio, by iCite: 148; iCite
Revised in PubMed: 2025-03-12; PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Sapolsky RM	R M
2	Romero LM	L M
3	Munck AU	A U

Source PubMed

Topics10

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Glucocorticoids	Major topic
Stress, Physiological	Major topic
Animals
Body Fluids
Cardiovascular System
Endocrinology
Humans
Inflammation
Nervous System
Reproduction

Source PubMed

Grants1

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by
DK-03535	NIDDK NIH HHS	United States	R01DK003535	PubMed and NIH

Source NIH RePORTER

Trials1

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

Trial	Title	The trial lists it as	Named in the paper's record
NCT03949569	The Effects of Therapy Dogs on Child Biology and Behavior	Background

Source ClinicalTrials.gov

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by2,317

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 5,115 citations.

PMID	Title	Journal	Year	In Papers	Source
42,953,348	Under pressure: personality, behavioural and physiological responses to handling in captive Addax nasomaculatus antelopes.	R Soc Open Sci	2026	https://conductscience.org/library/papers/42953348	PubMed
42,947,420	Evolutionary decoupling of morphological and behavioural antipredator responses and their hormonal basis across anuran species.	Proc Biol Sci	2026	https://conductscience.org/library/papers/42947420	PubMed
42,941,820	How the Acute Psychosocial Stress Response Ends: A Post-Stressor Transition Model of Glucocorticoid Feedback, Vagal Re-Engagement, and Frontolimbic Context Updating.	Int J Mol Sci	2026	https://conductscience.org/library/papers/42941820	PubMed
42,939,106	Cortisol in Saliva, Urine, Feces, and Hair as Non- and Minimally Invasive Measures of Adrenocortical Activity in Intensively Housed Pigs.	Animals (Basel)	2026	https://conductscience.org/library/papers/42939106	PubMed
42,936,501	The mind-body connection in women's reproductive health: how psychological stress shapes gut and ovarian function - a narrative review.	Front Gastroenterol (Lausanne)	2026	https://conductscience.org/library/papers/42936501	PubMed
42,904,794	Skiers' footprint on wildlife stress: Tracing the impact of winter sports on black grouse with interactive mapping.	Ecol Appl	2026	https://conductscience.org/library/papers/42904794	PubMed
42,903,907	Do wind energy installations alter gastrointestinal parasite infection patterns in roe deer (Capreolus capreolus L.) in central Poland?	Int J Parasitol Parasites Wildl	2026	https://conductscience.org/library/papers/42903907	PubMed
42,899,147	Glucocorticoids in breast cancer: physiologic mechanisms and relationship to risk, survival, and treatment response.	Front Endocrinol (Lausanne)	2026	https://conductscience.org/library/papers/42899147	PubMed
42,898,873	Effects of dietary threonine and arginine on growth performance, stress indicators, and gut health in broiler chickens under multiple stress.	J Anim Sci Technol	2026	https://conductscience.org/library/papers/42898873	PubMed
42,878,895	Threat-induced neural prioritization: a life history framework for energy allocation under chronic predator stress.	Oecologia	2026	https://conductscience.org/library/papers/42878895	PubMed

1 to 10 of 2,317

See all 2,317 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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