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Paper · 10857

Release of immunoreactive serotonin following acid perfusion of the duodenum.

Kellum JM and 1 other. Ann Surg, 1976. Cited by 66 papers, by iCite.

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ConductScience Library. Release of immunoreactive serotonin following acid perfusion of the duodenum. Papers, record 10857. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/10857

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Release of immunoreactive serotonin following acid perfusion of the duodenum.
PubMed
Journal
Ann Surg
PubMed
Year
1976
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
66
iCite
Relative citation ratio, by iCite
2.66
iCite
Revised in PubMed
2019-05-14
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Kellum JM JrJ M
2Jaffe BMB M

Source PubMed

Topics10

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
DuodenumMajor topic
SerotoninMajor topic
Animals
Dogs
Hepatic Veins
Hydrogen-Ion Concentration
Perfusion
Portal Vein
Radioimmunoassay
Vena Cava, Inferior

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References9

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
11,216,169Radioimmunoassay measurement of serotonin release following duodenal acidification.Surg Forum1975https://conductscience.org/library/papers/1216169PubMed
21,254,137Validation and application of a radioimmunoassay for serotonin.Gastroenterology1976https://conductscience.org/library/papers/1254137PubMed
65,951,5705-Hydroxytryptamine release into dog intestinal vasculature.Am J Physiol1966https://conductscience.org/library/papers/5951570PubMed
714,491,561Serotonin release by hydrochloric acid: possibility of a feed-back mechanism.Am J Physiol1961https://conductscience.org/library/papers/14491561PubMed
817,859,708Serotonin Release Following Instillation of Hypertonic Glucose into the Proximal Intestine.Ann Surg1962https://conductscience.org/library/papers/17859708PubMed
94,687,025Serotonin: radioimmunoassay.Science1973https://conductscience.org/library/papers/4687025PubMed
105,684,187Studies on the role of serotonin in the inhibition of gastric acid secretion by the duodenum.Ann Surg1968https://conductscience.org/library/papers/5684187PubMed
115,750,089Studies on the inhibiton of gastric secretion by the small intestine.Surg Gynecol Obstet1968https://conductscience.org/library/papers/5750089PubMed
1214,491,557Stimulation of gastric secretion in man by a serotonin antagonist.Gastroenterology1962https://conductscience.org/library/papers/14491557PubMed

Cited by12

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 66 citations.

PMIDTitleJournalYearIn PapersSource
34,070,942Gastric Serotonin Biosynthesis and Its Functional Role in L-Arginine-Induced Gastric Proton Secretion.Int J Mol Sci2021https://conductscience.org/library/papers/34070942PubMed
28,774,871Enteric serotonin and oxytocin: endogenous regulation of severity in a murine model of necrotizing enterocolitis.Am J Physiol Gastrointest Liver Physiol2017https://conductscience.org/library/papers/28774871PubMed
23,755,368Duodenal epithelial transport in functional dyspepsia: Role of serotonin.World J Gastrointest Pathophysiol2013https://conductscience.org/library/papers/23755368PubMed
17,874,119A cluster of gustducin-expressing cells in the mouse stomach associated with two distinct populations of enteroendocrine cells.Histochem Cell Biol2007https://conductscience.org/library/papers/17874119PubMed
17,457,962Neuropathophysiology of functional gastrointestinal disorders.World J Gastroenterol2007https://conductscience.org/library/papers/17457962PubMed
6,492,001Initiation of migrating myoelectric complex in sheep by duodenal acidification and hyperosmolarity: role of vagus nerves.J Physiol1984https://conductscience.org/library/papers/6492001PubMed
3,391,086Effects of intravenous calcium on release of serotonin into jejunal lumen and portal circulation.Dig Dis Sci1988https://conductscience.org/library/papers/3391086PubMed
2,891,037Cholinergic modulation of the release of 5-hydroxytryptamine from the guinea pig ileum.Naunyn Schmiedebergs Arch Pharmacol1987https://conductscience.org/library/papers/2891037PubMed
2,578,277The pentagastrin test in the diagnosis of the carcinoid syndrome. Blockade of gastrointestinal symptoms by ketanserin.Ann Surg1985https://conductscience.org/library/papers/2578277PubMed
2,428,162Pathogenesis and pharmacology of diarrhea.Vet Res Commun1986https://conductscience.org/library/papers/2428162PubMed

1 to 10 of 12

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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