Paper12819084

Development of DNA vaccines against hemolytic-uremic syndrome in a murine model.

Capozzo AV and 9 others. Infect Immun, 2003. Cited by 24 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Development of DNA vaccines against hemolytic-uremic syndrome in a murine model. Papers, record 12819084. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/12819084

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Development of DNA vaccines against hemolytic-uremic syndrome in a murine model.; PubMed
Journal: Infect Immun; PubMed
Year: 2003; PubMed
Publication types: Journal Article, Research Support, Non-U.S. Gov't; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/12819084/; PubMed
DOI: https://doi.org/10.1128/iai.71.7.3971-3978.2003; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC162006/; PubMed
The journal: https://conductscience.org/library/journal-index/0246127; PubMed
Citations, by iCite: 24; iCite
Relative citation ratio, by iCite: 0.69; iCite
Revised in PubMed: 2022-02-16; PubMed

Authors10

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Capozzo AV	Alejandra V E
2	Pistone Creydt V	Virginia
3	Dran G	Graciela
4	Fernández G	Gabriela
5	Gómez S	Sonia
6	Bentancor LV	Leticia V
7	Rubel C	Carolina
8	Ibarra C	Cristina
9	Isturiz M	Martín
10	Palermo MS	Marina S

Source PubMed

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Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Escherichia coli Vaccines	Major topic
Hemolytic-Uremic Syndrome	Major topic
Shiga Toxin 2	Major topic
Vaccines, DNA	Major topic
Animals
Antibodies, Bacterial
Disease Models, Animal
Immunoglobulin G
Mice
Mice, Inbred BALB C
Neutralization Tests
Plasmids
Transfection

Source PubMed

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References43

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	7,806,370	Expression and purification of Shiga-like toxin II B subunits.	Infect Immun	1995	https://conductscience.org/library/papers/7806370	PubMed
2	11,225,323	[Protection against influenza by genetically engineered vaccines].	Nihon Rinsho	2000	https://conductscience.org/library/papers/11225323	PubMed
3	9,435,018	Construction and characterization of versatile cloning vectors for efficient delivery of native foreign proteins to the periplasm of Escherichia coli.	Plasmid	1997	https://conductscience.org/library/papers/9435018	PubMed
4	9,256,266	Immunostimulatory DNA: a clear and present danger?	Nat Med	1997	https://conductscience.org/library/papers/9256266	PubMed
5	8,961,510	DNA immunization confers protective immunity on mice challenged intravaginally with herpes simplex virus type 2.	Vaccine	1996	https://conductscience.org/library/papers/8961510	PubMed
6	9,199,412	Localization of intravenously administered verocytotoxins (Shiga-like toxins) 1 and 2 in rabbits immunized with homologous and heterologous toxoids and toxin subunits.	Infect Immun	1997	https://conductscience.org/library/papers/9199412	PubMed
7	2,475,438	Expression of Shiga toxin epitopes in E. coli immunological characterization.	Immunol Lett	1989	https://conductscience.org/library/papers/2475438	PubMed
8	9,652,427	First human trial of a DNA-based vaccine for treatment of human immunodeficiency virus type 1 infection: safety and host response.	J Infect Dis	1998	https://conductscience.org/library/papers/9652427	PubMed
9	8,837,611	DNA-based immunization by in vivo transfection of dendritic cells.	Nat Med	1996	https://conductscience.org/library/papers/8837611	PubMed
10	9,298,210	Nuclei isolation from bone cells for nuclear run-on assays.	Biotechniques	1997	https://conductscience.org/library/papers/9298210	PubMed
11	9,234,543	Protective immunity induced by rotavirus DNA vaccines.	Vaccine	1997	https://conductscience.org/library/papers/9234543	PubMed
12	8,265,577	DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations.	Proc Natl Acad Sci U S A	1993	https://conductscience.org/library/papers/8265577	PubMed
13	11,110,647	Intervention with Shiga toxin (Stx) antibody after infection by Stx-producing Escherichia coli.	J Infect Dis	2001	https://conductscience.org/library/papers/11110647	PubMed
14	11,803,949	Induction of a th1-type of immune response but not protective immunity by intramuscular DNA immunisation with Brucella abortus GroEL heat-shock gene.	J Med Microbiol	2002	https://conductscience.org/library/papers/11803949	PubMed
15	9,175,848	Comparison of ribosome-inactivating proteins in the induction of apoptosis.	Toxicol Lett	1997	https://conductscience.org/library/papers/9175848	PubMed
16	2,047,652	Shiga toxin: purification, structure, and function.	Rev Infect Dis	1991	https://conductscience.org/library/papers/2047652	PubMed
17	3,095,828	Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase.	Proc Natl Acad Sci U S A	1986	https://conductscience.org/library/papers/3095828	PubMed
18	10,669,329	Vaccination of seronegative volunteers with a human immunodeficiency virus type 1 env/rev DNA vaccine induces antigen-specific proliferation and lymphocyte production of beta-chemokines.	J Infect Dis	2000	https://conductscience.org/library/papers/10669329	PubMed
19	12,021,709	Naked plasmid DNA encoding fibroblast growth factor type 1 for the treatment of end-stage unreconstructible lower extremity ischemia: preliminary results of a phase I trial.	J Vasc Surg	2002	https://conductscience.org/library/papers/12021709	PubMed
20	5,432,063	Cleavage of structural proteins during the assembly of the head of bacteriophage T4.	Nature	1970	https://conductscience.org/library/papers/5432063	PubMed

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Cited by10

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 24 citations.

PMID	Title	Journal	Year	In Papers	Source
30,637,647	Nano-multilamellar lipid vesicles (NMVs) enhance protective antibody responses against Shiga toxin (Stx2a) produced by enterohemorrhagic Escherichia coli strains (EHEC).	Braz J Microbiol	2019	https://conductscience.org/library/papers/30637647	PubMed
24,421,050	Protection of mice against Shiga toxin 2 (Stx2)-associated damage by maternal immunization with a Brucella lumazine synthase-Stx2 B subunit chimera.	Infect Immun	2014	https://conductscience.org/library/papers/24421050	PubMed
24,085,779	Promoter sequence of Shiga toxin 2 (Stx2) is recognized in vivo, leading to production of biologically active Stx2.	mBio	2013	https://conductscience.org/library/papers/24085779	PubMed
24,031,368	Antibody responses elicited in mice immunized with Bacillus subtilis vaccine strains expressing Stx2B subunit of enterohaemorragic Escherichia coli O157:H7.	Braz J Microbiol	2009	https://conductscience.org/library/papers/24031368	PubMed
22,479,186	Shiga toxin 1 induces on lipopolysaccharide-treated astrocytes the release of tumor necrosis factor-alpha that alter brain-like endothelium integrity.	PLoS Pathog	2012	https://conductscience.org/library/papers/22479186	PubMed
21,559,455	Antibody response to Shiga toxins in Argentinean children with enteropathic hemolytic uremic syndrome at acute and long-term follow-up periods.	PLoS One	2011	https://conductscience.org/library/papers/21559455	PubMed
20,147,499	Salmonella enterica serovar Typhimurium vaccine strains expressing a nontoxic Shiga-like toxin 2 derivative induce partial protective immunity to the toxin expressed by enterohemorrhagic Escherichia coli.	Clin Vaccine Immunol	2010	https://conductscience.org/library/papers/20147499	PubMed
19,176,691	A DNA vaccine encoding the enterohemorragic Escherichia coli Shiga-like toxin 2 A2 and B subunits confers protective immunity to Shiga toxin challenge in the murine model.	Clin Vaccine Immunol	2009	https://conductscience.org/library/papers/19176691	PubMed
16,177,337	Protection against hemorrhagic colitis in an animal model by oral immunization with isogeneic rabbit enteropathogenic Escherichia coli attenuated by truncating intimin.	Infect Immun	2005	https://conductscience.org/library/papers/16177337	PubMed
15,271,924	Mucosally delivered Salmonella live vector vaccines elicit potent immune responses against a foreign antigen in neonatal mice born to naive and immune mothers.	Infect Immun	2004	https://conductscience.org/library/papers/15271924	PubMed

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Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

None in this release

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ClinicalTrials.govNo license stated
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iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
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NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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