Paper · 135689

T cell proliferation in the mixed lymphocyte culture does not necessarily result in the generation of cytotoxic T effector cells.

Röllinghoff M and 3 others. Eur J Immunol, 1975. Cited by 52 papers, by iCite.

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ConductScience Library. T cell proliferation in the mixed lymphocyte culture does not necessarily result in the generation of cytotoxic T effector cells. Papers, record 135689. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/135689

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: T cell proliferation in the mixed lymphocyte culture does not necessarily result in the generation of cytotoxic T effector cells.; PubMed
Journal: Eur J Immunol; PubMed
Year: 1975; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/135689/; PubMed
DOI: https://doi.org/10.1002/eji.1830050811; PubMed
The journal: https://conductscience.org/library/journal-index/1273201; PubMed
Citations, by iCite: 52; iCite
Relative citation ratio, by iCite: 1.09; iCite
Revised in PubMed: 2003-11-14; PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Röllinghoff M	M
2	Pfizenmeier K	K
3	Trostmann H	H
4	Wagner H	H

Source PubMed

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Immunity, Cellular	Major topic
Isoantigens	Major topic
T-Lymphocytes	Major topic
Animals
Concanavalin A
Cytotoxicity Tests, Immunologic
Female
Histocompatibility Antigens
Lectins
Lipopolysaccharides
Lymphocyte Activation
Lymphocyte Culture Test, Mixed
Mice

Source PubMed

Grants0

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None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by15

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 52 citations.

PMID	Title	Journal	Year	In Papers	Source
7,373,222	Generation of primary cytotoxic lymphocytes against non-major histocompatibility complex antigens by anti-Ia serum plus complement-treated lymphocytes.	J Exp Med	1980	https://conductscience.org/library/papers/7373222	PubMed
6,455,762	T cell recognition of antigen in vivo: role of the H-2 complex.	Springer Semin Immunopathol	1980	https://conductscience.org/library/papers/6455762	PubMed
6,424,695	Proliferative patterns of lymphocytes in lymph nodes during tumour development: involvement of T and B cell areas.	Br J Cancer	1984	https://conductscience.org/library/papers/6424695	PubMed
6,215,457	Suppressor T cells activated in a primary in vitro response to non-major histocompatibility alloantigens.	J Exp Med	1982	https://conductscience.org/library/papers/6215457	PubMed
6,172,537	T cell clones with dual specificity for M1s and various major histocompatibility complex determinants.	J Exp Med	1981	https://conductscience.org/library/papers/6172537	PubMed
6,153,213	Absence of H-2 restriction in primary and secondary mixed-lymphocyte reactions to strong M1s determinants.	J Exp Med	1980	https://conductscience.org/library/papers/6153213	PubMed
1,085,422	T-T cell collaboration during in vivo responses to antigens coded by the peripheral and central region of the MHC.	Nature	1976	https://conductscience.org/library/papers/1085422	PubMed
1,082,492	Participation of the H-2 antigens of tumor cells in their lysis by syngeneic T cells.	J Exp Med	1976	https://conductscience.org/library/papers/1082492	PubMed
357,051	Effect of niridazole in cellular immunity in vivo and in vitro.	Clin Exp Immunol	1978	https://conductscience.org/library/papers/357051	PubMed
300,775	Secondary in vitro responses of T lymphocytes to non-H-2 alloantigens self-H-2-restricted responses induced in heterologous serum are not dependent on primary-stimulating non-H-2 alloantigens.	J Exp Med	1977	https://conductscience.org/library/papers/300775	PubMed

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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