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Paper · 14760

Prazosin, a selective antagonist of post-synaptic alpha-adrenoceptors [proceedings].

Cambridge D and 2 others. Br J Pharmacol, 1977. Cited by 371 papers, by iCite.

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ConductScience Library. Prazosin, a selective antagonist of post-synaptic alpha-adrenoceptors [proceedings]. Papers, record 14760. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/14760

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Prazosin, a selective antagonist of post-synaptic alpha-adrenoceptors [proceedings].
PubMed
Journal
Br J Pharmacol
PubMed
Year
1977
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
371
iCite
Relative citation ratio, by iCite
18.4
iCite
Revised in PubMed
2018-11-13
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Cambridge DD
2Davey MJM J
3Massingham RR

Source PubMed

Topics7

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Adrenergic alpha-AntagonistsMajor topic
PrazosinMajor topic
QuinazolinesMajor topic
SynapsesMajor topic
Animals
In Vitro Techniques
Rabbits

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References5

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
11,122,933A comparsion of the effects of prazosin and hydrallazine on blood pressure, heart rate and plasma renin activity in conscious renal hypertensive dogs.Eur J Pharmacol1975https://conductscience.org/library/papers/1122933PubMed
24,313,675The release of H3-norepinephrine in arterial strips studied by the technique of superfusion and transmural stimulation.J Pharmacol Exp Ther1970https://conductscience.org/library/papers/4313675PubMed
34,397,129Role of transmitter uptake mechanisms in synaptic neurotransmission.Br J Pharmacol1971https://conductscience.org/library/papers/4397129PubMed
44,617,579Presynaptic regulation of catecholamine release.Biochem Pharmacol1974https://conductscience.org/library/papers/4617579PubMed
5627Relative pre- and postsynaptic potencies of alpha-adrenoceptor agonists in the rabbit pulmonary artery.Naunyn Schmiedebergs Arch Pharmacol1975https://conductscience.org/library/papers/627PubMed

Cited by99

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 371 citations.

PMIDTitleJournalYearIn PapersSource
36,051,157Evolving Role of Silodosin for the Treatment of Urological Disorders - A Narrative Review.Drug Des Devel Ther2022https://conductscience.org/library/papers/36051157PubMed
27,287,619Reduced Noradrenergic Signaling in the Spleen Capsule in the Absence of CB1 and CB2 Cannabinoid Receptors.J Neuroimmune Pharmacol2016https://conductscience.org/library/papers/27287619PubMed
24,832,867Methylphenidate exerts dose-dependent effects on glutamate receptors and behaviors.Biol Psychiatry2014https://conductscience.org/library/papers/24832867PubMed
23,776,582High vascular tone of mouse femoral arteries in vivo is determined by sympathetic nerve activity via α1A- and α1D-adrenoceptor subtypes.PLoS One2013https://conductscience.org/library/papers/23776582PubMed
18,218,679Alpha-adrenergic inhibition increases collateral circuit conductance in rats following acute occlusion of the femoral artery.J Physiol2008https://conductscience.org/library/papers/18218679PubMed
16,170,328Evidence for involvement of alpha1D-adrenoceptors in contraction of femoral resistance arteries using knockout mice.Br J Pharmacol2005https://conductscience.org/library/papers/16170328PubMed
15,900,505Adrenoceptor heterogeneity in the ruminal epithelium of sheep.J Comp Physiol B2005https://conductscience.org/library/papers/15900505PubMed
11,986,395Post-junctional alpha-adrenoceptors and basal limb vascular tone in healthy men.J Physiol2002https://conductscience.org/library/papers/11986395PubMed
9,673,832Clinical pharmacokinetics of vasodilators. Part II.Clin Pharmacokinet1998https://conductscience.org/library/papers/9673832PubMed
8,096,456Involvement of alpha 2-adrenoceptors in mechanism of intragastric nicotine protection against ethanol injury in rat stomach.Dig Dis Sci1993https://conductscience.org/library/papers/8096456PubMed

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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