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Paper15304635

The pH of the secretory pathway: measurement, determinants, and regulation.

Paroutis P and 2 others. Physiology (Bethesda), 2004. Cited by 370 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. The pH of the secretory pathway: measurement, determinants, and regulation. Papers, record 15304635. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/15304635

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
The pH of the secretory pathway: measurement, determinants, and regulation.
PubMed
Journal
Physiology (Bethesda)
PubMed
Year
2004
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't, Review
PubMed
Citations, by iCite
370
iCite
Relative citation ratio, by iCite
7.49
iCite
Revised in PubMed
2022-03-01
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Paroutis PPaul
2Touret NNicolas
3Grinstein SSergio

Source PubMed

Topics6

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Acid-Base EquilibriumMajor topic
Hydrogen-Ion ConcentrationMajor topic
Secretory VesiclesMajor topic
Transport VesiclesMajor topic
Animals
Humans

Source PubMed

Cited by211

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 370 citations.

PMIDTitleJournalYearIn PapersSource
42,926,954Structure of human V-ATPase with the a2-isoform reveals a proton-release gate in the luminal half-channel.Res Sq2026https://conductscience.org/library/papers/42926954PubMed
42,516,764Alanine scanning of the yeast killer toxin K2 reveals key residues for activity, gain-of-function variants, and supports prediction of precursor processing and 3D structure.J Struct Biol X2026https://conductscience.org/library/papers/42516764PubMed
41,998,130Integrative structural analysis of the human LRP2-LRPAP1 complex reveals multiple regulatory sites.Commun Biol2026https://conductscience.org/library/papers/41998130PubMed
41,981,336HSV-1 strain H129 co-opts neuronal synaptic transmission machinery for its transsynaptic spread.Nat Neurosci2026https://conductscience.org/library/papers/41981336PubMed
41,612,036Biomolecular condensates sustain pH gradients at equilibrium through charge neutralization.Nat Chem2026https://conductscience.org/library/papers/41612036PubMed
41,214,333Mechanistic insights into cargo sorting and export from the Golgi apparatus.Nat Rev Mol Cell Biol2025https://conductscience.org/library/papers/41214333PubMed
41,136,318Organellar pH as an emerging vulnerability to exploit in cancer.Trends Cancer2026https://conductscience.org/library/papers/41136318PubMed
40,923,757Rational design of tunable pH switches through shadow-strand hybridization-actuated displacement engineering.Nucleic Acids Res2025https://conductscience.org/library/papers/40923757PubMed
40,897,699Structural insights into proprotein convertase activation facilitate the engineering of highly specific furin inhibitors.Nat Commun2025https://conductscience.org/library/papers/40897699PubMed
40,804,719Higher induction temperatures and the native secretion signal peptide promote rye prolamin 75k γ-secalin production in Komagataella phaffii.Microb Cell Fact2025https://conductscience.org/library/papers/40804719PubMed
40,776,447The role of hydrophobic collapse in cytotoxic and functional amyloid oligomerization.Biophys J2025https://conductscience.org/library/papers/40776447PubMed
40,682,834TRPML3‑mediated lysosomal Ca2+ release enhances drug sequestration and biogenesis, promoting osimertinib resistance in non‑small cell lung cancer.Oncol Rep2025https://conductscience.org/library/papers/40682834PubMed
40,057,589Isoaspartate-containing galanin in rat hypothalamus.Commun Chem2025https://conductscience.org/library/papers/40057589PubMed
39,875,630Rhodamine-functionalized carbon dots with pH-regulated FRET efficiency for ratiometric fluorescence sensing and imaging of extremely alkaline pH.Mikrochim Acta2025https://conductscience.org/library/papers/39875630PubMed
39,769,617Expression of Drosophila melanogaster V-ATPases in Olfactory Sensillum Support Cells.Insects2024https://conductscience.org/library/papers/39769617PubMed
39,512,880Chromogranin B Purification for Condensate Formation and Client Partitioning Assays In Vitro.Bio Protoc2024https://conductscience.org/library/papers/39512880PubMed
39,251,576Cytosolic FKBPL and ER-resident CKAP4 co-regulates ER-phagy and protein secretion.Nat Commun2024https://conductscience.org/library/papers/39251576PubMed
39,136,459The Rab6 post-Golgi secretory pathway contributes to herpes simplex virus 1 (HSV-1) egress.J Virol2024https://conductscience.org/library/papers/39136459PubMed
39,001,043An Insulin-Modified pH-Responsive Nanopipette Based on Ion Current Rectification.Sensors (Basel)2024https://conductscience.org/library/papers/39001043PubMed
38,888,935A genetically-encoded fluorescence-based reporter to spatiotemporally investigate mannose-6-phosphate pathway.Mol Biol Cell2024https://conductscience.org/library/papers/38888935PubMed

See all 211 cited by

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • References
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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