Paper · 15825317

Beta-lactamase activity in ampicillin-resistant Haemophilus influenzae.

Farrar WE and 1 other. Antimicrob Agents Chemother, 1974. Cited by 52 papers, by iCite.

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ConductScience Library. Beta-lactamase activity in ampicillin-resistant Haemophilus influenzae. Papers, record 15825317. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/15825317

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Beta-lactamase activity in ampicillin-resistant Haemophilus influenzae.; PubMed
Journal: Antimicrob Agents Chemother; PubMed
Year: 1974; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/15825317/; PubMed
DOI: https://doi.org/10.1128/aac.6.5.625; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC444704/; PubMed
The journal: https://conductscience.org/library/journal-index/0315061; PubMed
Citations, by iCite: 52; iCite
Relative citation ratio, by iCite: 2.27; iCite
Revised in PubMed: 2021-05-26; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Farrar WE Jr	W E
2	O'Dell NM	N M

Source PubMed

Topics5

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Ampicillin Resistance	Major topic
Haemophilus influenzae	Major topic
beta-Lactamases	Major topic
Microbial Sensitivity Tests
beta-Lactamase Inhibitors

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References10

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	5,326,329	Interaction of cephaloridine with penicillinase-producing gram-negative bacteria.	Nature	1965	https://conductscience.org/library/papers/5326329	PubMed
2	4,861,905	Hydrolysis of cephalosporins by beta-lactamases from gram-negative bacteria.	Nature	1967	https://conductscience.org/library/papers/4861905	PubMed
3	4,885,039	Elimination by ethidium bromide of antibiotic resistance in enterobacteria and staphylococci.	J Gen Microbiol	1968	https://conductscience.org/library/papers/4885039	PubMed
4	4,998,257	The -lactamases of gram-negative bacteria and their transfer by R-factors.	Pathol Microbiol (Basel)	1970	https://conductscience.org/library/papers/4998257	PubMed
5	13,952,353	Penicillinase from Klebsiella aerogenes. A comparison with penicillinases from gram-positive species.	Biochem J	1963	https://conductscience.org/library/papers/13952353	PubMed
6	4,342,044	Measurement of beta-lactamase activity and rate of inactivation of penicillins by a pH-stat alkalimetric titration method.	J Pharm Sci	1972	https://conductscience.org/library/papers/4342044	PubMed
7	4,130,492	Letter: Ampicillin-resistant Haemophilus influenzae meningitis.	Lancet	1974	https://conductscience.org/library/papers/4130492	PubMed
8	4,546,093	Ampicillin-resistant Haemophilus influenzae type B infection.	JAMA	1974	https://conductscience.org/library/papers/4546093	PubMed
9	4,546,094	Haemophilus influenzae type B resistant to ampicillin. A report of two cases.	JAMA	1974	https://conductscience.org/library/papers/4546094	PubMed
10	5,061,041	Penicillins in the treatment of bacterial meningitis.	J R Coll Physicians Lond	1972	https://conductscience.org/library/papers/5061041	PubMed

Cited by23

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 52 citations.

PMID	Title	Journal	Year	In Papers	Source
39,937,854	Spatial population dynamics of bacterial colonies with social antibiotic resistance.	Proc Natl Acad Sci U S A	2025	https://conductscience.org/library/papers/39937854	PubMed
18,747,627	Ampicillin resistant hemophilus influenzae: -a new dilemma.	West J Med	1976	https://conductscience.org/library/papers/18747627	PubMed
6,973,952	In vitro and in vivo synergism between amoxicillin and clavulanic acid against ampicillin-resistant Haemophilus influenzae type b.	Antimicrob Agents Chemother	1981	https://conductscience.org/library/papers/6973952	PubMed
6,968,540	Synergistic action of ampicillin and nafcillin against ampicillin-resistant Haemophilus influenzae.	Antimicrob Agents Chemother	1980	https://conductscience.org/library/papers/6968540	PubMed
6,271,052	In vitro susceptibility of Haemophilus influenzae and neisseria gonorrhoeae to Ro 13-9904 in comparison with other beta-lactam antibiotics.	Antimicrob Agents Chemother	1981	https://conductscience.org/library/papers/6271052	PubMed
3,134,225	Characterization of Haemophilus influenzae isolated from patients with otitis media.	Eur J Clin Microbiol Infect Dis	1988	https://conductscience.org/library/papers/3134225	PubMed
3,093,222	Emergence of beta-lactamase producing anaerobic bacteria in the tonsils during penicillin treatment.	Eur J Clin Microbiol	1986	https://conductscience.org/library/papers/3093222	PubMed
3,089,941	Impact on peritonsillar infections and microflora of phenoxymethylpenicillin alone versus phenoxymethylpenicillin in combination with metronidazole.	Infection	1986	https://conductscience.org/library/papers/3089941	PubMed
1,084,727	Characterization of an ampicillin-resistant Haemophilus influenzae type B.	Antimicrob Agents Chemother	1976	https://conductscience.org/library/papers/1084727	PubMed
1,083,200	Susceptibility of Haemophilus influenza to ampicillin as determined by use of a modified, one-minute beta-lactamase test.	Antimicrob Agents Chemother	1976	https://conductscience.org/library/papers/1083200	PubMed

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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