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Paper · 15944707

A microRNA polycistron as a potential human oncogene.

He L and 10 others. Nature, 2005. Cited by 2,942 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. A microRNA polycistron as a potential human oncogene. Papers, record 15944707. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/15944707

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
A microRNA polycistron as a potential human oncogene.
PubMed
Journal
Nature
PubMed
Year
2005
PubMed
Publication types
Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
2,942
iCite
Relative citation ratio, by iCite
58.3
iCite
Revised in PubMed
2025-02-13
PubMed

Authors11

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1He LLin
2Thomson JMJ Michael
3Hemann MTMichael T
4Hernando-Monge EEva
5Mu DDavid
6Goodson SSummer
7Powers SScott
8Cordon-Cardo CCarlos
9Lowe SWScott W
10Hannon GJGregory J

1 to 10 of 11Source PubMed

See all 11 authors

Topics17

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Gene Expression Regulation, NeoplasticMajor topic
GenesMajor topic
Lymphoma, B-CellMajor topic
MicroRNAsMajor topic
OncogenesMajor topic
Animals
Cell Line, Tumor
Disease Models, Animal
Gene Expression Profiling
Genes, myc
Humans
Mice
Molecular Sequence Data
Multigene Family
Phenotype
Proto-Oncogene Proteins c-myc
RNA, Messenger

Source PubMed

Grants2

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
P01 CA087497NCI NIH HHSUnited StatesP01CA087497PubMed and NIHNIH RePORTER
P30 CA008748NCI NIH HHSUnited StatesP30CA008748PubMed and NIHNIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections2

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

KindPMIDTitleIn PapersSource
Comment in15,944,682Cancer genomics: small RNAs with big impacts.https://conductscience.org/library/papers/15944682PubMed
Comment in16,009,126miRNAs, cancer, and stem cell division.https://conductscience.org/library/papers/16009126PubMed

References28

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
115,211,354MicroRNAs: small RNAs with a big role in gene regulation.Nat Rev Genet2004https://conductscience.org/library/papers/15211354PubMed
22,702,689A hierarchy of regulatory genes controls a larva-to-adult developmental switch in C. elegans.Cell1989https://conductscience.org/library/papers/2702689PubMed
314,973,191Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers.Proc Natl Acad Sci U S A2004https://conductscience.org/library/papers/14973191PubMed
414,657,504MicroRNAs modulate hematopoietic lineage differentiation.Science2004https://conductscience.org/library/papers/14657504PubMed
514,508,493The nuclear RNase III Drosha initiates microRNA processing.Nature2003https://conductscience.org/library/papers/14508493PubMed
614,695,998High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma.Genes Chromosomes Cancer2004https://conductscience.org/library/papers/14695998PubMed
714,573,789Reduced accumulation of specific microRNAs in colorectal neoplasia.Mol Cancer Res2003https://conductscience.org/library/papers/14573789PubMed
814,685,240A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans.Nature2003https://conductscience.org/library/papers/14685240PubMed
915,136,036Molecular evolution of a microRNA cluster.J Mol Biol2004https://conductscience.org/library/papers/15136036PubMed
1015,372,042The functions of animal microRNAs.Nature2004https://conductscience.org/library/papers/15372042PubMed

1 to 10 of 28

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Cited by1,773

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 2,942 citations.

PMIDTitleJournalYearIn PapersSource
42,657,538Dark matter matters: from noncoding RNA regulation to cancer immunity.Oncoimmunology2026https://conductscience.org/library/papers/42657538PubMed
42,650,040Non-Coding RNAs in Cancer Liquid Biopsy: From Regulatory Networks to Functional Biomarkers for Precision Oncology.Genes (Basel)2026https://conductscience.org/library/papers/42650040PubMed
42,584,802hnRNP A1 controls MIR17HG alternative splicing and maturation of miR-19a.Mol Biol Rep2026https://conductscience.org/library/papers/42584802PubMed
42,512,389Decoding Post-Transcriptional Networks Governing the Melanoma Extracellular Matrix.Cancers (Basel)2026https://conductscience.org/library/papers/42512389PubMed
42,481,418Greg Hannon: the scientist who changed biology, and the people who practiced it.Genes Dev2026https://conductscience.org/library/papers/42481418PubMed
42,352,254Extracellular MicroRNAs: A Stable and Diverse Source of Transcriptional Control.Biomolecules2026https://conductscience.org/library/papers/42352254PubMed
42,245,728miR-17: from developmental regulatory hub to molecular engine driving tumourigenesis.Front Oncol2026https://conductscience.org/library/papers/42245728PubMed
42,192,969miRNA-lncRNA Cross-Regulation Landscape in Cancer: From Molecular Mechanisms to Therapeutic and Diagnostic Applications.Cancers (Basel)2026https://conductscience.org/library/papers/42192969PubMed
41,670,044microRNA involvement in human cancer.Carcinogenesis2025https://conductscience.org/library/papers/41670044PubMed
41,649,513miRNA profiling in pediatric and young adult Burkitt leukemia and lymphoma.Virchows Arch2026https://conductscience.org/library/papers/41649513PubMed

1 to 10 of 1,773

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Genes3

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
MIR17406,952PubTator's text mininghttps://conductscience.org/library/genes/406952NCBI Gene
MIR17HG407,975PubTator's text mininghttps://conductscience.org/library/genes/407975NCBI Gene
MYC4,609PubTator's text mininghttps://conductscience.org/library/genes/4609NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data40

The data bank entries PubMed's record names. Trial numbers are under Trials.

Data bankAccessionSource
GENBANKGSM45026GENBANK
GENBANKGSM45027GENBANK
GENBANKGSM45028GENBANK
GENBANKGSM45029GENBANK
GENBANKGSM45030GENBANK
GENBANKGSM45031GENBANK
GENBANKGSM45032GENBANK
GENBANKGSM45033GENBANK
GENBANKGSM45034GENBANK
GENBANKGSM45035GENBANK

1 to 10 of 40

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Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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