Paper · 16169

The time course of cellular responses to iontophoretically applied drugs.

Purves RD. J Theor Biol, 1977. Cited by 35 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. The time course of cellular responses to iontophoretically applied drugs. Papers, record 16169. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/16169

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: The time course of cellular responses to iontophoretically applied drugs.; PubMed
Journal: J Theor Biol; PubMed
Year: 1977; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/16169/; PubMed
DOI: https://doi.org/10.1016/0022-5193(77)90328-9; PubMed
The journal: https://conductscience.org/library/journal-index/0376342; PubMed
Citations, by iCite: 35; iCite
Relative citation ratio, by iCite: 1.27; iCite
Revised in PubMed: 2019-07-24; PubMed

Authors1

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Purves RD	R D

Source PubMed

Topics10

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Iontophoresis	Major topic
Models, Biological	Major topic
Receptors, Drug	Major topic
Binding Sites
Cell Membrane
Electric Conductivity
Hydrolysis
Membrane Potentials
Neurotransmitter Agents
Time Factors

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by14

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 35 citations.

PMID	Title	Journal	Year	In Papers	Source
10,919,863	Cyclic nucleotide-gated channels colocalize with adenylyl cyclase in regions of restricted cAMP diffusion.	J Gen Physiol	2000	https://conductscience.org/library/papers/10919863	PubMed
9,276,752	Cyclic AMP levels, adenylyl cyclase activity, and their stimulation by serotonin quantified in intact neurons.	J Gen Physiol	1997	https://conductscience.org/library/papers/9276752	PubMed
7,965,847	Ionophoretically applied acetylcholine and vagal stimulation in the arrested sinus venosus of the toad, Bufo marinus.	J Physiol	1994	https://conductscience.org/library/papers/7965847	PubMed
7,338,810	Ion diffusion modified by tortuosity and volume fraction in the extracellular microenvironment of the rat cerebellum.	J Physiol	1981	https://conductscience.org/library/papers/7338810	PubMed
6,646,998	Effects of fast and slowly acting antagonists on the time course of the muscarinic response in guinea-pig atrial muscle.	Pflugers Arch	1983	https://conductscience.org/library/papers/6646998	PubMed
6,262,708	The time course of the muscarinic response to ionophoretic acetylcholine application to the S-A node of the rabbit heart.	Pflugers Arch	1981	https://conductscience.org/library/papers/6262708	PubMed
6,253,873	On the kinetics of the potassium channel activated by acetylcholine in the S-A node of the rabbit heart.	Pflugers Arch	1980	https://conductscience.org/library/papers/6253873	PubMed
3,040,972	Nicotinic acetylcholine receptors on a cholinergic nerve terminal in the cockroach, Periplaneta americana.	J Comp Physiol A	1987	https://conductscience.org/library/papers/3040972	PubMed
309,004	An analysis of the dose-response relationship at voltage-clamped frog neuromuscular junctions.	J Physiol	1978	https://conductscience.org/library/papers/309004	PubMed
309,003	Determination of dose-response curves by quantitative ionophoresis at the frog neuromuscular junction.	J Physiol	1978	https://conductscience.org/library/papers/309003	PubMed

1 to 10 of 14

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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