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Paper · 16200064

Probing tumor phenotypes using stable and regulated synthetic microRNA precursors.

Dickins RA and 6 others. Nat Genet, 2005. Cited by 448 papers, by iCite.

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ConductScience Library. Probing tumor phenotypes using stable and regulated synthetic microRNA precursors. Papers, record 16200064. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/16200064

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Probing tumor phenotypes using stable and regulated synthetic microRNA precursors.
PubMed
Journal
Nat Genet
PubMed
Year
2005
PubMed
Publication types
Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.
PubMed
Citations, by iCite
448
iCite
Relative citation ratio, by iCite
6.78
iCite
Revised in PubMed
2022-03-09
PubMed

Authors7

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Dickins RARoss A
2Hemann MTMichael T
3Zilfou JTJack T
4Simpson DRDavid R
5Ibarra IIngrid
6Hannon GJGregory J
7Lowe SWScott W

Source PubMed

Topics18

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Genetic VectorsMajor topic
MicroRNAsMajor topic
NeoplasmsMajor topic
RNA InterferenceMajor topic
RNA Polymerase IIMajor topic
RNA, Small InterferingMajor topic
Animals
Cell Proliferation
Cellular Senescence
Fibroblasts
Mice
Oncogenes
Phenotype
Promoter Regions, Genetic
Protein Synthesis Inhibitors
Tetracycline
Transcription, Genetic
Tumor Suppressor Protein p53

Source PubMed

Grants1

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated by
P30 CA008748NCI NIH HHSUnited StatesP30CA008748PubMed and NIH

Source NIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections1

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

KindPMIDTitleIn Papers
Comment in16,254,559RNAi the natural way.https://conductscience.org/library/papers/16254559

Source PubMed

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by296

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 448 citations.

PMIDTitleJournalYearIn PapersSource
42,629,473Metastasis of triple negative breast cancer is regulated by a targetable miR-342-E2F network.EMBO Mol Med2026https://conductscience.org/library/papers/42629473PubMed
42,333,811Dual function of ERH in primary miRNA biogenesis.Nucleic Acids Res2026https://conductscience.org/library/papers/42333811PubMed
42,137,586High-titer modular retroviral vectors enabled by an antisense cassette design preventing dsRNA formation during virus production.Mol Ther Adv2026https://conductscience.org/library/papers/42137586PubMed
41,606,720KLHDC3 deficiency in mice reveals essential roles in development, survival, and adiposity via the DesCEND ubiquitin pathway.BMC Genomics2026https://conductscience.org/library/papers/41606720PubMed
41,426,227Gamma-retrovirus design for efficacious microRNA-mediated gene knock-down and protein co-expression without compromising titers.NAR Mol Med2025https://conductscience.org/library/papers/41426227PubMed
41,215,730Impaired nuclear PTEN function drives macrocephaly, lymphadenopathy and late-onset cancer in PTEN hamartoma tumour syndrome.Dis Model Mech2026https://conductscience.org/library/papers/41215730PubMed
40,558,465A Smart Nanoprobe for Visually Investigating the Activation Effect of Cyclical DOX Release on the p53 Pathway and Pathway-Related Molecules.Biosensors (Basel)2025https://conductscience.org/library/papers/40558465PubMed
39,967,915The Role of MicroRNAs in Liver Functioning: from Biogenesis to Therapeutic Approaches (Review).Sovrem Tekhnologii Med2023https://conductscience.org/library/papers/39967915PubMed
39,524,539Recent advances in methylation modifications of microRNA.Genes Dis2025https://conductscience.org/library/papers/39524539PubMed
39,043,718Mutational profiling of SARS-CoV-2 papain-like protease reveals requirements for function, structure, and drug escape.Nat Commun2024https://conductscience.org/library/papers/39043718PubMed

1 to 10 of 296

See all 296 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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