Paper165503

Regulation of herpesvirus macromolecular synthesis: sequential transition of polypeptide synthesis requires functional viral polypeptides.

Honess RW and 1 other. Proc Natl Acad Sci U S A, 1975. Cited by 535 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Cite this record

ConductScience Library. Regulation of herpesvirus macromolecular synthesis: sequential transition of polypeptide synthesis requires functional viral polypeptides. Papers, record 165503. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/165503

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Regulation of herpesvirus macromolecular synthesis: sequential transition of polypeptide synthesis requires functional viral polypeptides.; PubMed
Journal: Proc Natl Acad Sci U S A; PubMed
Year: 1975; PubMed
Publication types: Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/165503/; PubMed
DOI: https://doi.org/10.1073/pnas.72.4.1276; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC432515/; PubMed
The journal: https://conductscience.org/library/journal-index/7505876; PubMed
Citations, by iCite: 535; iCite
Relative citation ratio, by iCite: 10.8; iCite
Revised in PubMed: 2019-05-01; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Honess RW	R W
2	Roizman B	B

Source PubMed

Topics11

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Peptide Biosynthesis	Major topic
Protein Biosynthesis	Major topic
Simplexvirus	Major topic
Viral Proteins	Major topic
Azetidinecarboxylic Acid
Canavanine
Computers
Cycloheximide
Electrophoresis, Polyacrylamide Gel
Peptides
Time Factors

Source PubMed

Show 5 more topicsShow fewer topics

References6

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	4,301,595	Polypeptide cleavages in the formation of poliovirus proteins.	Proc Natl Acad Sci U S A	1968	https://conductscience.org/library/papers/4301595	PubMed
2	4,318,205	Further evidence on the formation of poliovirus proteins.	J Mol Biol	1970	https://conductscience.org/library/papers/4318205	PubMed
3	4,357,511	Proteins specified by herpes simplex virus. XI. Identification and relative molar rates of synthesis of structural and nonstructural herpes virus polypeptides in the infected cell.	J Virol	1973	https://conductscience.org/library/papers/4357511	PubMed
4	4,365,321	Regulation of herpesvirus macromolecular synthesis. I. Cascade regulation of the synthesis of three groups of viral proteins.	J Virol	1974	https://conductscience.org/library/papers/4365321	PubMed
5	4,369,085	Proteins specified by herpes simplex virus. XII. The virion polypeptides of type 1 strains.	J Virol	1974	https://conductscience.org/library/papers/4369085	PubMed
6	4,373,710	Regulation of herpesvirus macromolecular synthesis: nuclear retention of nontranslated viral RNA sequences.	Proc Natl Acad Sci U S A	1974	https://conductscience.org/library/papers/4373710	PubMed

Cited by346

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 535 citations.

PMID	Title	Journal	Year	In Papers	Source
42,748,108	Analysis of host and viral nascent and steady-state RNA levels in a human neuronal model of herpes simplex virus 1 infection.	PLoS Pathog	2026	https://conductscience.org/library/papers/42748108	PubMed
41,746,146	Cell type-specific differences in herpes simplex virus type 1 infection and dependency on ICP27.	J Virol	2026	https://conductscience.org/library/papers/41746146	PubMed
41,685,901	The accessibility of the HSV genome during productive infection can vary in different cell types and affect the outcome of infection.	mBio	2026	https://conductscience.org/library/papers/41685901	PubMed
40,874,743	Camptothecin, a topoisomerase I inhibitor, impedes productive herpes simplex virus type 1 infection.	J Virol	2025	https://conductscience.org/library/papers/40874743	PubMed
40,537,528	Herpes simplex virus type 1 reshapes host chromatin architecture via transcription machinery hijacking.	Nat Commun	2025	https://conductscience.org/library/papers/40537528	PubMed
39,920,420	Recurrence of herpetic keratouveitis following cataract surgery.	Int Ophthalmol	2025	https://conductscience.org/library/papers/39920420	PubMed
38,932,138	Identifying Protein Interactions with Viral DNA Genomes during Virus Infection.	Viruses	2024	https://conductscience.org/library/papers/38932138	PubMed
38,817,634	Integrator Complex Subunit 3 Knockdown Has Minimal Effect on Lytic Herpes Simplex Virus Type-1 Infection in Fibroblast Cells.	MicroPubl Biol	2024	https://conductscience.org/library/papers/38817634	PubMed
38,543,571	Major Virion Tegument Protein VP22 Targets Nuclear Matrix and Chromatin upon Entry into Cells during Productive Herpes Simplex Virus 1 Infection.	Microorganisms	2024	https://conductscience.org/library/papers/38543571	PubMed
37,764,935	HSV-1 Triggers an Antiviral Transcriptional Response during Viral Replication That Is Completely Abrogated in PKR-/- Cells.	Pathogens	2023	https://conductscience.org/library/papers/37764935	PubMed
37,575,180	Alphaherpesvirus-mediated remodeling of the cellular transcriptome results in depletion of m6A-containing transcripts.	iScience	2023	https://conductscience.org/library/papers/37575180	PubMed
37,515,145	ICP4-Associated Activation of Rap1b Facilitates Herpes Simplex Virus Type I (HSV-1) Infection in Human Corneal Epithelial Cells.	Viruses	2023	https://conductscience.org/library/papers/37515145	PubMed
37,486,931	Proliferating cell nuclear antigen inhibitors block distinct stages of herpes simplex virus infection.	PLoS Pathog	2023	https://conductscience.org/library/papers/37486931	PubMed
37,361,241	Anti-HSV nucleoside and non-nucleoside analogues: spectroscopic characterisation of naphthyl and coumarinyl amides and their mode and mechanism of antiviral action.	3 Biotech	2023	https://conductscience.org/library/papers/37361241	PubMed
37,271,042	Herpes simplex virus infected cell protein 8 is required for viral inhibition of the cGAS pathway.	Virology	2023	https://conductscience.org/library/papers/37271042	PubMed
36,968,465	Temperature-induced reactivation of Marek's disease virus-transformed T cells ex vivo.	Front Vet Sci	2023	https://conductscience.org/library/papers/36968465	PubMed
36,535,877	Better late than never: A unique strategy for late gene transcription in the beta- and gammaherpesviruses.	Semin Cell Dev Biol	2023	https://conductscience.org/library/papers/36535877	PubMed
36,016,945	When liquid-liquid phase separation meets viral infections.	Front Immunol	2022	https://conductscience.org/library/papers/36016945	PubMed
35,638,820	Mouse Mx1 Inhibits Herpes Simplex Virus Type 1 Genomic Replication and Late Gene Expression In Vitro and Prevents Lesion Formation in the Mouse Zosteriform Model.	J Virol	2022	https://conductscience.org/library/papers/35638820	PubMed
35,608,347	DLK-Dependent Biphasic Reactivation of Herpes Simplex Virus Latency Established in the Absence of Antivirals.	J Virol	2022	https://conductscience.org/library/papers/35608347	PubMed

Show 14 more cited byShow fewer cited bySee all 346 cited by

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

None in this release

Grants
Trials
Comments and corrections
Genes
Drugs
Data

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/165503

GET https://conductscience.org/api/papers/v1/165503/cited_by?page=2

API reference For AI assistants