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Paper · 165672

Biologic regulation through opposing influences of cyclic GMP and cyclic AMP: the Yin Yang hypothesis.

Goldberg ND and 6 others. Adv Cyclic Nucleotide Res, 1975. Cited by 231 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Biologic regulation through opposing influences of cyclic GMP and cyclic AMP: the Yin Yang hypothesis. Papers, record 165672. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/165672

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Biologic regulation through opposing influences of cyclic GMP and cyclic AMP: the Yin Yang hypothesis.
PubMed
Journal
Adv Cyclic Nucleotide Res
PubMed
Year
1975
PubMed
Publication types
Journal Article, Review
PubMed
Citations, by iCite
231
iCite
Relative citation ratio, by iCite
6.72
iCite
Revised in PubMed
2013-11-21
PubMed

Authors7

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Goldberg NDN D
2Haddox MKM K
3Nicol SES E
4Glass DBD B
5Sanford CHC H
6Kuehl FA JrF A
7Estensen RR

Source PubMed

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Cyclic AMPMajor topic
Cyclic GMPMajor topic
Acetylcholine
Animals
Atropine
Cell Division
Choline
Diethylstilbestrol
Estradiol
Female
Guinea Pigs
Heart
Kinetics
Models, Biological
Rats
Uterus

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by87

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 231 citations.

PMIDTitleJournalYearIn PapersSource
39,959,196Establishment and evaluation of a rat model of cervical spondylosis with Yin deficiency syndrome.Am J Transl Res2025https://conductscience.org/library/papers/39959196PubMed
37,971,403Phosphodiesterase in heart and vessels: from physiology to diseases.Physiol Rev2024https://conductscience.org/library/papers/37971403PubMed
37,521,477The pharmacological effects and safety of the raw and prepared folium of Epimedium brevicornu Maxim. on improving kidney-yang deficiency syndrome and sexual dysfunction.Front Pharmacol2023https://conductscience.org/library/papers/37521477PubMed
36,819,533Effects of decoction of Angelica Sinensis, Zingiberis Rhizoma Recens, and mutton on physiology and biochemistry of Sprague Dawley female rats with spleen-kidney Yang deficiency.Ann Transl Med2023https://conductscience.org/library/papers/36819533PubMed
36,429,131The Role of NO/sGC/cGMP/PKG Signaling Pathway in Regulation of Platelet Function.Cells2022https://conductscience.org/library/papers/36429131PubMed
34,513,121UHPLC-MS/MS analysis of cAMP and cGMP in rat plasma as potential biomarkers of Yin-Yang disharmony in traditional Chinese medicine.J Pharm Anal2021https://conductscience.org/library/papers/34513121PubMed
34,462,649Changes in Humans' Autonomic Nervous System under Dynamic Lighting Environment During A Short Rest.J Healthc Eng2021https://conductscience.org/library/papers/34462649PubMed
33,271,627Cyclic nucleotide selectivity of protein kinase G isozymes.Protein Sci2021https://conductscience.org/library/papers/33271627PubMed
32,179,768The control mechanisms of heart rate dynamics in a new heart rate nonlinear time series model.Sci Rep2020https://conductscience.org/library/papers/32179768PubMed
31,388,518Neuro-autonomic changes induced by remote ischemic preconditioning (RIPC) in healthy young adults: Implications for stress.Neurobiol Stress2019https://conductscience.org/library/papers/31388518PubMed

1 to 10 of 87

See all 87 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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