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Paper166202

Anatomy of herpes simplex virus DNA. III. Characterization of defective DNA molecules and biological properties of virus populations containing them.

Frenkel N and 5 others. J Virol, 1975. Cited by 129 papers, by iCite.

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ConductScience Library. Anatomy of herpes simplex virus DNA. III. Characterization of defective DNA molecules and biological properties of virus populations containing them. Papers, record 166202. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/166202

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Anatomy of herpes simplex virus DNA. III. Characterization of defective DNA molecules and biological properties of virus populations containing them.
PubMed
Journal
J Virol
PubMed
Year
1975
PubMed
Publication types
Comparative Study, Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
129
iCite
Relative citation ratio, by iCite
3.08
iCite
Revised in PubMed
2020-07-24
PubMed

Authors6

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Frenkel NN
2Jacob RJR J
3Honess RWR W
4Hayward GSG S
5Locker HH
6Roizman BB

Source PubMed

Topics17

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
DNA, ViralMajor topic
Defective VirusesMajor topic
SimplexvirusMajor topic
Carcinoma, Squamous Cell
Cell Line
Centrifugation, Density Gradient
DNA Restriction Enzymes
Electrophoresis, Polyacrylamide Gel
Formaldehyde
Humans
Laryngeal Neoplasms
Microscopy, Electron
Nucleic Acid Denaturation
Peptide Biosynthesis
Viral Interference
Viral Proteins
Virus Replication

Source PubMed

References27

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
14,354,250Detection of two restriction endonuclease activities in Haemophilus parainfluenzae using analytical agarose--ethidium bromide electrophoresis.Biochemistry1973https://conductscience.org/library/papers/4354250PubMed
25,417,647Simplified quantitative electron microscopy of biopolymers.Biopolymers1970https://conductscience.org/library/papers/5417647PubMed
34,372,357Triplication of a unique genetic segment in a simian virus 40-like virus of human origin and evolution of new viral genomes.J Mol Biol1974https://conductscience.org/library/papers/4372357PubMed
413,742,866A physical difference between two strains of herpes simplex virus apparent on sedimentation in cesium chloride.Virology1961https://conductscience.org/library/papers/13742866PubMed
513,982,497The programming of herpes virus multiplication in doubly-infected and in puromycin-treated cells.Proc Natl Acad Sci U S A1963https://conductscience.org/library/papers/13982497PubMed
64,129,836Proteins specified by herpes simplex virus. Staining and radiolabeling properties of B capsid and virion proteins in polyacrylamide gels.J Virol1974https://conductscience.org/library/papers/4129836PubMed
74,316,015Preparation of herpes simplex virus of high titer.J Virol1968https://conductscience.org/library/papers/4316015PubMed
84,329,966Size, composition, and structure of the deoxyribonucleic acid of herpes simplex virus subtypes 1 and 2.J Virol1971https://conductscience.org/library/papers/4329966PubMed
913,999,204Electron microscopic particle counts on herpes virus using the phosphotungstate negative staining technique.Virology1963https://conductscience.org/library/papers/13999204PubMed
104,300,104Characterization of herpes simplex virus strains differing in their effects on social behaviour of infected cells.J Gen Virol1968https://conductscience.org/library/papers/4300104PubMed
114,356,530Defective interfering viruses.Annu Rev Microbiol1973https://conductscience.org/library/papers/4356530PubMed
125,312,500A restriction enzyme from Hemophilus influenzae. I. Purification and general properties.J Mol Biol1970https://conductscience.org/library/papers/5312500PubMed
134,369,849Characterization of defective interfering viral particles present in a population of pseudorabies virions.Virology1974https://conductscience.org/library/papers/4369849PubMed
144,357,511Proteins specified by herpes simplex virus. XI. Identification and relative molar rates of synthesis of structural and nonstructural herpes virus polypeptides in the infected cell.J Virol1973https://conductscience.org/library/papers/4357511PubMed
155,450,519Partial denaturation of thymine- and 5-bromouracil-containing lambda DNA in alkali.J Mol Biol1970https://conductscience.org/library/papers/5450519PubMed
1611,947,496A solubilizable acrylamide gel for electrophoresis.FEBS Lett1970https://conductscience.org/library/papers/11947496PubMed
174,362,640The isolation of simian virus 40 variants with specifically altered genomes.Proc Natl Acad Sci U S A1974https://conductscience.org/library/papers/4362640PubMed
1813,997,383Equilibrium sedimentation of macromolecules and viruses in a density gradient.Fortschr Chem Org Naturst1962https://conductscience.org/library/papers/13997383PubMed
194,355,850Acquisition of sequences homologous to host DNA by closed circular simian virus 40 DNA. II. Further studies on the serial passage of virus clones.J Virol1973https://conductscience.org/library/papers/4355850PubMed
204,359,757Defective virions of herpes simplex viruses.Intervirology1973https://conductscience.org/library/papers/4359757PubMed

See all 27 references

Cited by54

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 129 citations.

PMIDTitleJournalYearIn PapersSource
40,827,854The producer cell type of HSV-1 alters the proteomic contents and infectious capacity of virions.J Virol2025https://conductscience.org/library/papers/40827854PubMed
37,991,369Shared sequence characteristics identified in non-canonical rearrangements of HSV-1 genomes.J Virol2023https://conductscience.org/library/papers/37991369PubMed
25,365,323Rad51 and Rad52 are involved in homologous recombination of replicating herpes simplex virus DNA.PLoS One2014https://conductscience.org/library/papers/25365323PubMed
24,574,404Defective interfering influenza virus RNAs: time to reevaluate their clinical potential as broad-spectrum antivirals?J Virol2014https://conductscience.org/library/papers/24574404PubMed
24,227,835Evolution and diversity in human herpes simplex virus genomes.J Virol2014https://conductscience.org/library/papers/24227835PubMed
23,027,939Alphaherpesvirus axon-to-cell spread involves limited virion transmission.Proc Natl Acad Sci U S A2012https://conductscience.org/library/papers/23027939PubMed
16,873,277Eclipse phase of herpes simplex virus type 1 infection: Efficient dynein-mediated capsid transport without the small capsid protein VP26.J Virol2006https://conductscience.org/library/papers/16873277PubMed
16,352,574
The herpes simplex virus type 1 vhs-UL41 gene secures viral replication by temporarily evading apoptotic cellular response to infection: Vhs-UL41 activity might require interactions with elements of cellular mRNA degradation machinery.
J Virol2006https://conductscience.org/library/papers/16352574PubMed
16,148,307Molecular biology of pseudorabies virus: impact on neurovirology and veterinary medicine.Microbiol Mol Biol Rev2005https://conductscience.org/library/papers/16148307PubMed
9,060,466Microtubule-mediated transport of incoming herpes simplex virus 1 capsids to the nucleus.J Cell Biol1997https://conductscience.org/library/papers/9060466PubMed
8,876,131The function of herpes simplex virus genes: a primer for genetic engineering of novel vectors.Proc Natl Acad Sci U S A1996https://conductscience.org/library/papers/8876131PubMed
8,523,542Expression of an equine herpesvirus 1 ICP22/ICP27 hybrid protein encoded by defective interfering particles associated with persistent infection.J Virol1996https://conductscience.org/library/papers/8523542PubMed
7,853,470Cloning and characterization of herpes simplex virus type 1 oriL: comparison of replication and protein-DNA complex formation by oriL and oriS.J Virol1995https://conductscience.org/library/papers/7853470PubMed
7,037,648Detection of an immediate early herpes simplex virus type 1 polypeptide in trigeminal ganglia from latently infected animals.Infect Immun1981https://conductscience.org/library/papers/7037648PubMed
6,320,779DNA labeled during phosphonoacetate inhibition and following its reversal in herpesvirus infected cells.Arch Virol1984https://conductscience.org/library/papers/6320779PubMed
6,312,096Class I defective herpes simplex virus DNA as a molecular cloning vehicle in eucaryotic cells.J Virol1983https://conductscience.org/library/papers/6312096PubMed
6,302,703Identification of a rare Epstein-Barr virus variant that enhances early antigen expression in Raji cells.Proc Natl Acad Sci U S A1983https://conductscience.org/library/papers/6302703PubMed
6,287,032Structure and expression of class II defective herpes simplex virus genomes encoding infected cell polypeptide number 8.J Virol1982https://conductscience.org/library/papers/6287032PubMed
6,270,384Varicella-zoster virus vaccine DNA differs from the parental virus DNA.J Virol1981https://conductscience.org/library/papers/6270384PubMed
6,268,822Amplification of a short nucleotide sequence in the repeat units of defective herpes simplex virus type 1 Angelotti DNA.J Virol1981https://conductscience.org/library/papers/6268822PubMed

See all 54 cited by

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

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Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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