Paper166384

Adenosine 3':5'-cyclic monophosphate as mediator of catabolite repression in Escherichia coli.

Epstein W and 2 others. Proc Natl Acad Sci U S A, 1975. Cited by 231 papers, by iCite.

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ConductScience Library. Adenosine 3':5'-cyclic monophosphate as mediator of catabolite repression in Escherichia coli. Papers, record 166384. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/166384

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Adenosine 3':5'-cyclic monophosphate as mediator of catabolite repression in Escherichia coli.; PubMed
Journal: Proc Natl Acad Sci U S A; PubMed
Year: 1975; PubMed
Publication types: Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/166384/; PubMed
DOI: https://doi.org/10.1073/pnas.72.6.2300; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC432745/; PubMed
The journal: https://conductscience.org/library/journal-index/7505876; PubMed
Citations, by iCite: 231; iCite
Relative citation ratio, by iCite: 5.77; iCite
Revised in PubMed: 2019-05-01; PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Epstein W	W
2	Rothman-Denes LB	L B
3	Hesse J	J

Source PubMed

Topics7

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Cyclic AMP	Major topic
Escherichia coli	Major topic
Galactosidases	Major topic
Glucose
Glucosephosphates
Glycerol
Kinetics

Source PubMed

Show 1 more topicsShow fewer topics

References17

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	4,310,317	Pleiotropic deficiency of carbohydrate utilization in an adenyl cyclase deficient mutant of Escherichia coli.	Biochem Biophys Res Commun	1969	https://conductscience.org/library/papers/4310317	PubMed
2	4,317,896	Cyclic adenosine monophosphate in bacteria.	Science	1970	https://conductscience.org/library/papers/4317896	PubMed
3	4,317,918	Cyclic AMP receptor protein of E. coli: its role in the synthesis of inducible enzymes.	Proc Natl Acad Sci U S A	1970	https://conductscience.org/library/papers/4317918	PubMed
4	4,320,461	Mechanism of activation of catabolite-sensitive genes: a positive control system.	Proc Natl Acad Sci U S A	1970	https://conductscience.org/library/papers/4320461	PubMed
5	4,326,772	Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane.	Biochemistry	1971	https://conductscience.org/library/papers/4326772	PubMed
6	4,346,806	Cyclic adenosine 3',5'-monophosphate-dependent protein kinase of human erythrocyte membranes.	J Biol Chem	1972	https://conductscience.org/library/papers/4346806	PubMed
7	4,351,384	Role of cyclic adenosine 3',5'-monophosphate in the in vivo expression of the galactose operon of Escherichia coli.	J Bacteriol	1973	https://conductscience.org/library/papers/4351384	PubMed
8	4,351,386	Cyclic adenosine 3',5'-monophosphate in Escherichia coli.	J Bacteriol	1973	https://conductscience.org/library/papers/4351386	PubMed
9	4,364,236	Are cyclic AMP effects related to real physiological phenomena?	Biochem Biophys Res Commun	1974	https://conductscience.org/library/papers/4364236	PubMed
10	4,364,540	Cyclic 3':5'-adenosine monophosphate in Escherichia coli during transient and catabolite repression.	Proc Natl Acad Sci U S A	1974	https://conductscience.org/library/papers/4364540	PubMed
11	4,366,761	Glucose inhibition of adenylate cyclase in intact cells of Escherichia coli B.	Proc Natl Acad Sci U S A	1974	https://conductscience.org/library/papers/4366761	PubMed
12	4,568,762	Linkage map of Escherichia coli strain K-12.	Bacteriol Rev	1972	https://conductscience.org/library/papers/4568762	PubMed
13	4,583,241	Genetic characterization of mutations which affect catabolite-sensitive operons in Escherichia coli, including deletions of the gene for adenyl cyclase.	J Bacteriol	1973	https://conductscience.org/library/papers/4583241	PubMed
14	4,605,337	The selectivity of transcription.	Annu Rev Biochem	1974	https://conductscience.org/library/papers/4605337	PubMed
15	4,923,073	Isolation and mapping of phosphotransferase mutants in Escherichia coli.	J Bacteriol	1970	https://conductscience.org/library/papers/4923073	PubMed
16	4,942,756	Potassium transport loci in Escherichia coli K-12.	J Bacteriol	1971	https://conductscience.org/library/papers/4942756	PubMed
17	5,338,805	Catabolite repression of beta-galactosidase synthesis in Escherichia coli.	Biochem J	1966	https://conductscience.org/library/papers/5338805	PubMed

Show 11 more referencesShow fewer references

Cited by105

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 231 citations.

PMID	Title	Journal	Year	In Papers	Source
42,226,104	The dual role of cAMP receptor protein (CRP) in regulating type 3 fimbriae expression in Klebsiella pneumoniae CG43S3 in response to oxygen availability.	BMC Microbiol	2026	https://conductscience.org/library/papers/42226104	PubMed
42,070,967	In Salmonella Typhimurium, YiiD Modulates cAMP Levels in Lag Phase During Growth on Succinate.	Mol Microbiol	2026	https://conductscience.org/library/papers/42070967	PubMed
40,950,604	cAMP-CRP-activated E. coli causes growth arrest under stress conditions.	Front Microbiol	2025	https://conductscience.org/library/papers/40950604	PubMed
40,281,270	Optimization of growth and induction conditions for the production of recombinant whole cell cyclohexanone monooxygenase in Escherichia coli.	Sci Rep	2025	https://conductscience.org/library/papers/40281270	PubMed
37,017,526	Structural Basis of Dual Specificity of Sinorhizobium meliloti Clr, a cAMP and cGMP Receptor Protein.	mBio	2023	https://conductscience.org/library/papers/37017526	PubMed
36,480,614	Principles of gene regulation quantitatively connect DNA to RNA and proteins in bacteria.	Science	2022	https://conductscience.org/library/papers/36480614	PubMed
36,376,406	Shaping bacterial gene expression by physiological and proteome allocation constraints.	Nat Rev Microbiol	2023	https://conductscience.org/library/papers/36376406	PubMed
36,343,262	Sequestration of a dual function DNA-binding protein by Vibrio cholerae CRP.	Proc Natl Acad Sci U S A	2022	https://conductscience.org/library/papers/36343262	PubMed
35,065,916	Inducer exclusion, by itself, cannot account for the glucose-mediated lac repression of Escherichia coli.	Biophys J	2022	https://conductscience.org/library/papers/35065916	PubMed
35,065,914	Positive feedback exists and drives the glucose-mediated repression in Escherichia coli.	Biophys J	2022	https://conductscience.org/library/papers/35065914	PubMed
34,360,641	Fluorescence Spectroscopic Analysis of ppGpp Binding to cAMP Receptor Protein and Histone-Like Nucleoid Structuring Protein.	Int J Mol Sci	2021	https://conductscience.org/library/papers/34360641	PubMed
33,795,512	Bacterial-induced pH shifts link individual cell physiology to macroscale collective behavior.	Proc Natl Acad Sci U S A	2021	https://conductscience.org/library/papers/33795512	PubMed
33,650,807	Escherichia coli segments its controls on carbon-dependent gene expression into global and specific regulations.	Microb Biotechnol	2021	https://conductscience.org/library/papers/33650807	PubMed
27,974,467	Cyclic AMP Inhibits the Activity and Promotes the Acetylation of Acetyl-CoA Synthetase through Competitive Binding to the ATP/AMP Pocket.	J Biol Chem	2017	https://conductscience.org/library/papers/27974467	PubMed
27,076,065	Reduced expression of cytochrome oxidases largely explains cAMP inhibition of aerobic growth in Shewanella oneidensis.	Sci Rep	2016	https://conductscience.org/library/papers/27076065	PubMed
26,260,461	Positive Effect of Carbon Sources on Natural Transformation in Escherichia coli: Role of Low-Level Cyclic AMP (cAMP)-cAMP Receptor Protein in the Derepression of rpoS.	J Bacteriol	2015	https://conductscience.org/library/papers/26260461	PubMed
26,243,263	The bactericidal activity of β-lactam antibiotics is increased by metabolizable sugar species.	Microbiology (Reading)	2015	https://conductscience.org/library/papers/26243263	PubMed
25,255,314	Memory and fitness optimization of bacteria under fluctuating environments.	PLoS Genet	2014	https://conductscience.org/library/papers/25255314	PubMed
24,976,172	Bacterial sugar utilization gives rise to distinct single-cell behaviours.	Mol Microbiol	2014	https://conductscience.org/library/papers/24976172	PubMed
24,860,555	Recombinant protein expression in Escherichia coli: advances and challenges.	Front Microbiol	2014	https://conductscience.org/library/papers/24860555	PubMed

Show 14 more cited byShow fewer cited bySee all 105 cited by

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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PMC's ID filePublic domain (US government)
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UniProtCC BY 4.0

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