Paper · 166604

Restriction endonucleases in the analysis and restructuring of dna molecules.

Nathans D and 1 other. Annu Rev Biochem, 1975. Cited by 328 papers, by iCite.

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ConductScience Library. Restriction endonucleases in the analysis and restructuring of dna molecules. Papers, record 166604. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/166604

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Restriction endonucleases in the analysis and restructuring of dna molecules.; PubMed
Journal: Annu Rev Biochem; PubMed
Year: 1975; PubMed
Publication types: Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S., Review; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/166604/; PubMed
DOI: https://doi.org/10.1146/annurev.bi.44.070175.001421; PubMed
The journal: https://conductscience.org/library/journal-index/2985150R; PubMed
Citations, by iCite: 328; iCite
Relative citation ratio, by iCite: 7.04; iCite
Revised in PubMed: 2009-10-27; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Nathans D	D
2	Smith HO	H O

Source PubMed

Topics18

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
DNA	Major topic
DNA Restriction Enzymes	Major topic
Endonucleases	Major topic
Base Sequence
Binding Sites
Chromosome Mapping
Coliphages
DNA Replication
DNA, Viral
Escherichia coli
Genes
Methods
Models, Biological
Mutation
Polynucleotide Ligases
Recombination, Genetic
Simian virus 40
Transcription, Genetic

Source PubMed

Grants0

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None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

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Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

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Cited by117

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 328 citations.

PMID	Title	Journal	Year	In Papers	Source
42,631,273	Discontinuous genomic coding and paradigm shifts in molecular biology and immunology: revolutions via "normal science".	Nat Sci (Weinh)	2026	https://conductscience.org/library/papers/42631273	PubMed
41,174,236	A gasdermin-based life-death evolution system for reprogramming protease specificity.	Nat Chem Biol	2026	https://conductscience.org/library/papers/41174236	PubMed
40,823,824	The evolutionary replacement of restriction-modification by Ssp antiviral systems is associated with the distribution of prophages in the major clonal group of Acinetobacter baumannii.	mBio	2025	https://conductscience.org/library/papers/40823824	PubMed
40,724,860	Recombinant DNA the Bio-Revolution, Between Promise, Hurdles, and Achievements.	Int J Mol Sci	2025	https://conductscience.org/library/papers/40724860	PubMed
40,464,582	Diffdigester.uni-jena.de: a tool for optimized selection of restriction enzymes for plasmid identification in cloning procedures.	Nucleic Acids Res	2025	https://conductscience.org/library/papers/40464582	PubMed
38,870,284	A phage tail-like bacteriocin suppresses competitors in metapopulations of pathogenic bacteria.	Science	2024	https://conductscience.org/library/papers/38870284	PubMed
37,648,466	Cloning of human Type I interferon cDNAs.	Proc Jpn Acad Ser B Phys Biol Sci	2024	https://conductscience.org/library/papers/37648466	PubMed
37,213,492	Characterization and genomic analysis of phage vB_ValR_NF, representing a new viral family prevalent in the Ulva prolifera blooms.	Front Microbiol	2023	https://conductscience.org/library/papers/37213492	PubMed
36,721,089	PP-DDP: a privacy-preserving outsourcing framework for solving the double digest problem.	BMC Bioinformatics	2023	https://conductscience.org/library/papers/36721089	PubMed
34,159,713	History of the methodology of disease gene identification.	Am J Med Genet A	2021	https://conductscience.org/library/papers/34159713	PubMed

1 to 10 of 117

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Genes0

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None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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