Paper16868
Regulation of enzyme synthesis by the glutamine synthetase of Salmonella typhimurium: a factor in addition to glutamine synthetase is required for activation of enzyme formation.
Bloom FR and 2 others. J Bacteriol, 1977. Cited by 13 papers, by iCite.
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ConductScience Library. Regulation of enzyme synthesis by the glutamine synthetase of Salmonella typhimurium: a factor in addition to glutamine synthetase is required for activation of enzyme formation. Papers, record 16868. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/16868
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Regulation of enzyme synthesis by the glutamine synthetase of Salmonella typhimurium: a factor in addition to glutamine synthetase is required for activation of enzyme formation.
- PubMed
Topics12
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Enzymes | Major topic |
| Glutamate-Ammonia Ligase | Major topic |
| Salmonella typhimurium | Major topic |
| Amino Acid Oxidoreductases | |
| Enzyme Activation | |
| Escherichia coli | |
| Genes, Regulator | |
| Genotype | |
| Histidine Ammonia-Lyase | |
| Klebsiella | |
| Nitrogen | |
| Proline |
Source PubMed
References30
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 14,104 | Biochemical parameters of glutamine synthetase from Klebsiella aerogenes. | J Bacteriol | 1977 | https://conductscience.org/library/papers/14104 | PubMed |
| 2 | 14,114 | Regulation of glnA messinger ribonucleic acid synthesis in Klebsiella aerogenes. | J Bacteriol | 1977 | https://conductscience.org/library/papers/14114 | PubMed |
| 4 | 169,230 | Tryptophan biosynthesis in Salmonella typhimurium: location in trpB of a genetic difference between strains LT2 and LT7. | J Bacteriol | 1975 | https://conductscience.org/library/papers/169230 | PubMed |
| 5 | 1,744 | Regulation of synthesis of glutamine synthetase by adenylylated glutamine synthetase. | Proc Natl Acad Sci U S A | 1975 | https://conductscience.org/library/papers/1744 | PubMed |
| 6 | 192,833 | Expression of Klebsiella nif and his genes in Salmonella typhimurium. | J Gen Microbiol | 1977 | https://conductscience.org/library/papers/192833 | PubMed |
| 7 | 234,939 | Genetic control of glutamine synthetase in Klebiella aerogenes. | J Bacteriol | 1975 | https://conductscience.org/library/papers/234939 | PubMed |
| 8 | 238,935 | Mutations affecting glutamine synthetase activity in Salmonella typhimurium. | J Bacteriol | 1975 | https://conductscience.org/library/papers/238935 | PubMed |
| 9 | 238,937 | Gene order of the histidine utilization (hut) operons in Klebsiella aerogenes. | J Bacteriol | 1975 | https://conductscience.org/library/papers/238937 | PubMed |
| 10 | 240,804 | Regulation of the ammonia assimilatory enzymes in Salmonella typhimurium. | J Bacteriol | 1975 | https://conductscience.org/library/papers/240804 | PubMed |
| 11 | 3,494 | Transduction of chromosomal genes between enteric bacteria by bacteriophage P1. | J Bacteriol | 1976 | https://conductscience.org/library/papers/3494 | PubMed |
| 12 | 4,125,585 | Comparative biochemical and immunological studies of bacterial glutamine synthetases. | J Bacteriol | 1973 | https://conductscience.org/library/papers/4125585 | PubMed |
| 13 | 4,145,798 | Glutamine synthetase and the regulation of histidase formation in Klebsiella aerogenes. | J Biol Chem | 1973 | https://conductscience.org/library/papers/4145798 | PubMed |
| 14 | 4,146,916 | Regulation of the synthesis of enzymes responsible for glutamate formation in Klebsiella aerogenes. | J Biol Chem | 1973 | https://conductscience.org/library/papers/4146916 | PubMed |
| 15 | 4,149,344 | Activation of transcription of hut DNA by glutamine synthetase. | Proc Natl Acad Sci U S A | 1974 | https://conductscience.org/library/papers/4149344 | PubMed |
| 16 | 4,153,588 | Glutamine synthetase and ammonium regulation of nitrogenase synthesis in Klebsiella. | Nature | 1974 | https://conductscience.org/library/papers/4153588 | PubMed |
| 17 | 4,153,589 | Glutamine synthetase as a regulator of enzyme synthesis. | Curr Top Cell Regul | 1974 | https://conductscience.org/library/papers/4153589 | PubMed |
| 18 | 4,156,359 | Regulation of nitrogen fixation in Klebsiella pneumoniae: evidence for a role of glutamine synthetase as a regulator of nitrogenase synthesis. | J Bacteriol | 1974 | https://conductscience.org/library/papers/4156359 | PubMed |
| 19 | 4,331,387 | Resistance to catabolite repression of histidase and proline oxidase during nitrogen-limited growth of Klebsiella aerogenes. | J Biol Chem | 1971 | https://conductscience.org/library/papers/4331387 | PubMed |
| 20 | 4,577,136 | Isolation of the self-regulated repressor protein of the Hut operons of Salmonella typhimurium. | Proc Natl Acad Sci U S A | 1973 | https://conductscience.org/library/papers/4577136 | PubMed |
| 21 | 4,598,005 | Direct selection for P1-sensitive mutants of enteric bacteria. | J Bacteriol | 1974 | https://conductscience.org/library/papers/4598005 | PubMed |
Cited by10
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 13 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 28,972,974 | Differential inhibition of adenylylated and deadenylylated forms of M. tuberculosis glutamine synthetase as a drug discovery platform. | PLoS One | 2017 | https://conductscience.org/library/papers/28972974 | PubMed |
| 21,749,731 | The role of the C8 proton of ATP in the regulation of phosphoryl transfer within kinases and synthetases. | BMC Biochem | 2011 | https://conductscience.org/library/papers/21749731 | PubMed |
| 6,102,985 | Regulation of nitrogen metabolism in glutamine auxotrophs of Klebsiella pneumoniae. | J Bacteriol | 1980 | https://conductscience.org/library/papers/6102985 | PubMed |
| 6,102,984 | Purification of glutamine synthetase from a variety of bacteria. | J Bacteriol | 1980 | https://conductscience.org/library/papers/6102984 | PubMed |
| 6,102,551 | Regulation of Klebsiella pneumoniae hut operons by oxygen. | J Bacteriol | 1980 | https://conductscience.org/library/papers/6102551 | PubMed |
| 6,102,550 | Isolation of Klebsiella aerogenes mutants cis-dominant for glutamine synthetase expression. | J Bacteriol | 1980 | https://conductscience.org/library/papers/6102550 | PubMed |
| 2,254,273 | Cloning of the Klebsiella aerogenes nac gene, which encodes a factor required for nitrogen regulation of the histidine utilization (hut) operons in Salmonella typhimurium. | J Bacteriol | 1990 | https://conductscience.org/library/papers/2254273 | PubMed |
| 35,515 | Relation between the adenylylation state of glutamine synthetase and the expression of other genes involved in nitrogen metabolism. | J Bacteriol | 1979 | https://conductscience.org/library/papers/35515 | PubMed |
| 30,754 | Salmonella typhimurium LT-2 mutants with altered glutamine synthetase levels and amino acid uptake activities. | J Bacteriol | 1978 | https://conductscience.org/library/papers/30754 | PubMed |
| 22,535 | gltB gene and regulation of nitrogen metabolism by glutamine synthetase in Escherichia coli. | J Bacteriol | 1978 | https://conductscience.org/library/papers/22535 | PubMed |
Genes2
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| GLUL | 2,752 | PubTator's text mining | https://conductscience.org/library/genes/2752 | NCBI Gene |
| HAL | 3,034 | PubTator's text mining | https://conductscience.org/library/genes/3034 | NCBI Gene |
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
None in this release
- Grants
- Trials
- Comments and corrections
- Drugs
- Data
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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