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Paper · 17360992

The failing heart--an engine out of fuel.

Neubauer S. N Engl J Med, 2007. Cited by 1,955 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. The failing heart--an engine out of fuel. Papers, record 17360992. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/17360992

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
The failing heart--an engine out of fuel.
PubMed
Journal
N Engl J Med
PubMed
Year
2007
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't, Review
PubMed
Citations, by iCite
1,955
iCite
Relative citation ratio, by iCite
46.8
iCite
Revised in PubMed
2022-03-21
PubMed

Authors1

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Neubauer SStefan

Source PubMed

Topics14

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Energy MetabolismMajor topic
Heart FailureMajor topic
MyocardiumMajor topic
Adenosine Triphosphate
Animals
Creatine Kinase
Fatty Acids
Humans
Metabolism, Inborn Errors
Mice
Mice, Knockout
Oxidation-Reduction
Oxidative Phosphorylation
Peroxisome Proliferator-Activated Receptors

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials1

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

TrialTitleThe trial lists it asNamed in the paper's record
NCT06054516Hyperpolarized MRSI in Ischemic Heart Disease: A Metabolic Investigation of the Heart MuscleBackground

Comments and corrections7

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

KindPMIDTitleIn PapersSource
Comment in17,568,040The failing heart.https://conductscience.org/library/papers/17568040PubMed
Comment in17,575,594The failing heart.https://conductscience.org/library/papers/17575594PubMed
Comment in17,575,595The failing heart.https://conductscience.org/library/papers/17575595PubMed
Comment in17,575,596The failing heart.https://conductscience.org/library/papers/17575596PubMed
Comment in17,575,597The failing heart.https://conductscience.org/library/papers/17575597PubMed
Comment in17,575,598The failing heart.https://conductscience.org/library/papers/17575598PubMed
Comment in17,575,599The failing heart.https://conductscience.org/library/papers/17575599PubMed

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by1,194

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 1,955 citations.

PMIDTitleJournalYearIn PapersSource
42,942,905Nicotinamide Mononucleotide Does Not Prevent Cardiac Hypertrophy but Attenuates Cardiac Stress and Remodeling Markers in Mice Exposed to Intermittent Normobaric Hypoxia.Nutrients2026https://conductscience.org/library/papers/42942905PubMed
42,926,467Cardiomyocyte Perm1 sustains cardiac bioenergetic reserve and exercise capacity.bioRxiv2026https://conductscience.org/library/papers/42926467PubMed
42,909,325Mitochondrial remodeling in heart failure with reduced ejection fraction.Front Physiol2026https://conductscience.org/library/papers/42909325PubMed
42,869,600Effectiveness and safety of coenzyme Q10 in people with heart failure with preserved ejection fraction (HFpEF): a systematic review and meta-analysis.BMJ Open2026https://conductscience.org/library/papers/42869600PubMed
42,849,439Immunoregulatory gene GIMAP6 suppresses lethal atherosclerotic vasculopathy and ischemic heart failure.Cell2026https://conductscience.org/library/papers/42849439PubMed
42,849,122Histone Demethylase KDM5A Is Activated and Pathogenic in a Mouse Model of LMNA-Cardiomyopathy.JACC Basic Transl Sci2026https://conductscience.org/library/papers/42849122PubMed
42,792,238White Wine Intake Reduces Mitochondrial Complex I-Derived ROS in the Male Rat Heart.Antioxidants (Basel)2026https://conductscience.org/library/papers/42792238PubMed
42,792,193CYP2D6 as an Emerging Endogenous Oxidative Stress Modulator in Cardiovascular Disease: Genetic, Pharmacological, and Redox Perspectives.Antioxidants (Basel)2026https://conductscience.org/library/papers/42792193PubMed
42,786,201Cardiovascular-kidney-metabolic syndrome as a mitochondrial systems disorder.Nat Rev Nephrol2026https://conductscience.org/library/papers/42786201PubMed
42,769,776METTL3-Mediated N6-Methyladenosine Modification Activates the EGR1-ZBP1 Axis to Promote PANoptosis-Like Cardiomyocyte Death in Myocardial Ischemia-Reperfusion Injury.MedComm (2020)2026https://conductscience.org/library/papers/42769776PubMed

1 to 10 of 1,194

See all 1,194 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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