Paper · 17529971

A ROCK inhibitor permits survival of dissociated human embryonic stem cells.

Watanabe K and 10 others. Nat Biotechnol, 2007. Cited by 1,629 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Cite this record

ConductScience Library. A ROCK inhibitor permits survival of dissociated human embryonic stem cells. Papers, record 17529971. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/17529971

On this page

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: A ROCK inhibitor permits survival of dissociated human embryonic stem cells.; PubMed
Journal: Nat Biotechnol; PubMed
Year: 2007; PubMed
Publication types: Journal Article, Research Support, Non-U.S. Gov't; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/17529971/; PubMed
DOI: https://doi.org/10.1038/nbt1310; PubMed
The journal: https://conductscience.org/library/journal-index/9604648; PubMed
Citations, by iCite: 1,629; iCite
Relative citation ratio, by iCite: 33.3; iCite
Revised in PubMed: 2024-01-04; PubMed

Authors11

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Watanabe K	Kiichi
2	Ueno M	Morio
3	Kamiya D	Daisuke
4	Nishiyama A	Ayaka
5	Matsumura M	Michiru
6	Wataya T	Takafumi
7	Takahashi JB	Jun B
8	Nishikawa S	Satomi
9	Nishikawa S	Shin-ichi
10	Muguruma K	Keiko

1 to 10 of 11Source PubMed

See all 11 authors

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Amides	Major topic
Cell Differentiation	Major topic
Cell Survival	Major topic
Embryonic Stem Cells	Major topic
Intracellular Signaling Peptides and Proteins	Major topic
Protein Serine-Threonine Kinases	Major topic
Pyridines	Major topic
Animals
Cells, Cultured
Dose-Response Relationship, Drug
Humans
Mice
rho-Associated Kinases

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by1,029

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 1,629 citations.

PMID	Title	Journal	Year	In Papers	Source
42,946,741	NDE1-Mediated Regulation of Neural Progenitor Regional Identity and Its Implication in Microcephaly.	Nat Commun	2026	https://conductscience.org/library/papers/42946741	PubMed
42,944,734	Examining the Impact of Neurodevelopmental Nicotine Exposure on Cortical Excitation/Inhibition Homeostasis Markers in a Cerebral Organoid Model of Schizophrenia.	J Neurochem	2026	https://conductscience.org/library/papers/42944734	PubMed
42,920,066	Effect of Rho Kinase Inhibitor (Y27632) on Spermatogenesis in Azoospermic Mice Model.	Reprod Sci	2026	https://conductscience.org/library/papers/42920066	PubMed
42,846,680	Hippo-YAP/TAZ signaling in inner ear development, injury, and regeneration: evidence synthesis and the biomechanical brake hypothesis.	Front Cell Dev Biol	2026	https://conductscience.org/library/papers/42846680	PubMed
42,822,448	ROCK inhibition suppresses host blastomere-mediated elimination and enhances trophoblast stem cell contribution in mouse chimeras.	Stem Cell Reports	2026	https://conductscience.org/library/papers/42822448	PubMed
42,747,837	Morphogen-Directed, High-Throughput Development of hiPSC-Derived Telencephalic Organoids for Comparative In Vitro Phenotyping.	Curr Protoc	2026	https://conductscience.org/library/papers/42747837	PubMed
42,733,592	Construction and application of mammary and breast cancer organoids.	Cell Insight	2026	https://conductscience.org/library/papers/42733592	PubMed
42,732,516	Clinical-Grade Cryopreservation of Human-Induced Pluripotent Stem Cells.	Methods Mol Biol	2026	https://conductscience.org/library/papers/42732516	PubMed
42,730,405	Apoptosis: Reprogramming and the Fate of Mature Cells.	ISRN Cell Biol	2012	https://conductscience.org/library/papers/42730405	PubMed
42,671,510	From Design to Single-Cell Cloning: A Complete RNP-Based CRISPR-Cas9 Protocol for Precision Gene Correction in Human iPSCs.	Stem Cell Rev Rep	2026	https://conductscience.org/library/papers/42671510	PubMed

1 to 10 of 1,029

See all 1,029 cited by

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes
FOXG1	2,290	PubTator's text mining	https://conductscience.org/library/genes/2290

Source NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/17529971

GET https://conductscience.org/api/papers/v1/17529971/cited_by?page=2

API reference For AI assistants