Paper · 17545691

Clinical implications of founder and recurrent CDH1 mutations in hereditary diffuse gastric cancer.

Kangelaris KN and 1 other. JAMA, 2007. Cited by 13 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Clinical implications of founder and recurrent CDH1 mutations in hereditary diffuse gastric cancer. Papers, record 17545691. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/17545691

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Clinical implications of founder and recurrent CDH1 mutations in hereditary diffuse gastric cancer.; PubMed
Journal: JAMA; PubMed
Year: 2007; PubMed
Publication types: Editorial, Comment; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/17545691/; PubMed
DOI: https://doi.org/10.1001/jama.297.21.2410; PubMed
The journal: https://conductscience.org/library/journal-index/7501160; PubMed
Citations, by iCite: 13; iCite
Relative citation ratio, by iCite: 0.27; iCite
Revised in PubMed: 2018-12-01; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Kangelaris KN	Kirsten N
2	Gruber SB	Stephen B

Source PubMed

Topics9

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Cadherins	Major topic
Germ-Line Mutation	Major topic
Stomach Neoplasms	Major topic
Antigens, CD
DNA Mutational Analysis
Founder Effect
Haplotypes
Humans
Mutation

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections1

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

Kind	PMID	Title	In Papers
Comment on	17,545,690	Founder and recurrent CDH1 mutations in families with hereditary diffuse gastric cancer.	https://conductscience.org/library/papers/17545690

Source PubMed

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by8

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 13 citations.

PMID	Title	Journal	Year	In Papers	Source
37,505,767	Analysis of E-cadherin (CDH1) Gene Polymorphism and Its Association with Cervical Cancer Risk in Bangladeshi Women.	Asian Pac J Cancer Prev	2023	https://conductscience.org/library/papers/37505767	PubMed
30,975,222	Recent advances of therapeutic targets based on the molecular signature in breast cancer: genetic mutations and implications for current treatment paradigms.	J Hematol Oncol	2019	https://conductscience.org/library/papers/30975222	PubMed
29,285,016	Higher risk of progressing breast cancer in Kurdish population associated to CDH1 -160 C/A polymorphism.	EXCLI J	2017	https://conductscience.org/library/papers/29285016	PubMed
27,349,965	The CDH1 -160C/A polymorphism is associated with breast cancer: evidence from a meta-analysis.	World J Surg Oncol	2016	https://conductscience.org/library/papers/27349965	PubMed
27,067,391	A unified analytic framework for prioritization of non-coding variants of uncertain significance in heritable breast and ovarian cancer.	BMC Med Genomics	2016	https://conductscience.org/library/papers/27067391	PubMed
23,586,058	Hereditary breast cancer: the era of new susceptibility genes.	Biomed Res Int	2013	https://conductscience.org/library/papers/23586058	PubMed
22,535,324	CDH1 gene polymorphisms, plasma CDH1 levels and risk of gastric cancer in a Chinese population.	Mol Biol Rep	2012	https://conductscience.org/library/papers/22535324	PubMed
19,671,196	Absence of germline mono-allelic promoter hypermethylation of the CDH1 gene in gastric cancer patients.	Mol Cancer	2009	https://conductscience.org/library/papers/19671196	PubMed

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes
CDH1	999	PubTator's text mining	https://conductscience.org/library/genes/999

Source NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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