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Paper · 17569110

Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond.

Pencina MJ and 3 others. Stat Med, 2008. Cited by 5,604 papers, by iCite.

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ConductScience Library. Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond. Papers, record 17569110. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/17569110

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond.
PubMed
Journal
Stat Med
PubMed
Year
2008
PubMed
Publication types
Journal Article, Research Support, N.I.H., Extramural
PubMed
Citations, by iCite
5,604
iCite
Relative citation ratio, by iCite
150
iCite
Revised in PubMed
2022-04-10
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Pencina MJMichael J
2D'Agostino RB SrRalph B
3D'Agostino RB JrRalph B
4Vasan RSRamachandran S

Source PubMed

Topics8

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Cardiovascular DiseasesMajor topic
ROC CurveMajor topic
Risk AssessmentMajor topic
Risk FactorsMajor topic
Area Under Curve
Humans
Models, Statistical
United States

Source PubMed

Grants2

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
2 K24 HL04334NHLBI NIH HHSUnited StatesK24HL004334PubMed and NIHNIH RePORTER
N01 HC25195NHLBI NIH HHSUnited StatesN01HC025195PubMed and NIHNIH RePORTER

Trials2

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

TrialTitleThe trial lists it asNamed in the paper's recordSource
NCT06839963Kinshasa Lung Ultrasound Approach ValidationBackgroundClinicalTrials.gov
NCT07930429The MInimizing RIsk of CLotting Events TrialBackgroundClinicalTrials.gov

Comments and corrections9

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

KindPMIDTitleIn PapersSource
Comment in17,579,927
Comments on 'Evaluating the added predictive ability of a new marker: From area under the ROC curve to reclassification and beyond' by M. J. Pencina, R. B. D'Agostino Sr, R. B. D'Agostino Jr, R. S. Vasan, Statistics in Medicine (DOI: 10.1002/sim.2929).
https://conductscience.org/library/papers/17579927PubMed
Comment in17,668,917
Comments on 'Evaluating the added predictive ability of a new marker: From area under the ROC curve to reclassification and beyond' by M. J. Pencina et al., Statistics in Medicine (DOI: 10.1002/sim.2929).
https://conductscience.org/library/papers/17668917PubMed
Comment in17,671,958
Comments on 'Evaluating the added predictive ability of a new marker: From area under the ROC curve to reclassification and beyond' by M. J. Pencina et al., Statistics in Medicine (DOI: 10.1002/sim.2929).
https://conductscience.org/library/papers/17671958PubMed
Comment in17,671,959
Comments on 'Evaluating the added predictive ability of a new marker: From area under the ROC curve to reclassification and beyond' by M. J. Pencina et al., Statistics in Medicine (DOI: 10.1002/sim.2929).
https://conductscience.org/library/papers/17671959PubMed
Comment in17,712,782
The need for reorientation toward cost-effective prediction: comments on 'Evaluating the added predictive ability of a new marker: From area under the ROC curve to reclassification and beyond' by Pencina et al., Statistics in Medicine (DOI: 10.1002/sim.2929).
https://conductscience.org/library/papers/17712782PubMed
Comment in17,729,377
The need for reorientation toward cost-effective prediction: comments on 'Evaluating the added predictive ability of a new marker: From area under the ROC curve to reclassification and beyond' by M. J. Pencina et al., Statistics in Medicine (DOI: 10.1002/sim.2929).
https://conductscience.org/library/papers/17729377PubMed
Comment in17,907,248Net reclassification improvement and decision theory.https://conductscience.org/library/papers/17907248PubMed
Comment in18,041,049Comments on 'Evaluating the added predictive ability of a new marker' by M. Pencina, R. D'Agostino, R. D'Agostino Jr, R. Vasan, Statistics in Medicine (DOI: 10.1002/sim.2929).https://conductscience.org/library/papers/18041049PubMed
Comment in20,027,623Integrated discrimination improvement and probability-sensitive AUC variants.https://conductscience.org/library/papers/20027623PubMed

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by3,137

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 5,604 citations.

PMIDTitleJournalYearIn PapersSource
42,989,318Integrating machine learning and traditional statistics to evaluate the Uric acid-to-HDL cholesterol ratio for identification of prevalent COPD in older adults.Lipids Health Dis2026https://conductscience.org/library/papers/42989318PubMed
42,985,521Performance, Recalibration, and Implementation of In-Hospital Mortality Prediction Models for Myocardial Infarction.Rev Cardiovasc Med2026https://conductscience.org/library/papers/42985521PubMed
42,983,283Routine metabolic-adiposity indices and incident cardiometabolic multimorbidity among adults with CKM stages 0-3: a prospective cohort study.BMC Cardiovasc Disord2026https://conductscience.org/library/papers/42983283PubMed
42,978,645Associations of insulin resistance surrogates with cardiovascular disease in early stage cardiovascular-kidney-metabolic syndrome: a prospective cohort study.Front Cardiovasc Med2026https://conductscience.org/library/papers/42978645PubMed
42,973,573NLR-TyG index and prevalent chronic kidney disease in hypertension: a cross-population study.Front Nutr2026https://conductscience.org/library/papers/42973573PubMed
42,968,076Association between PCSK9 and post-stroke cognitive impairment: a retrospective cohort study and predictive models establishment based on machine learning.BMC Neurol2026https://conductscience.org/library/papers/42968076PubMed
42,966,860
Cumulative estimated glucose disposal rate and longitudinal eGDR patterns in relation to incident cardiovascular disease among middle-aged and older adults with metabolic dysfunction-associated steatotic liver disease: a prospective cohort study.
Cardiovasc Diabetol2026https://conductscience.org/library/papers/42966860PubMed
42,964,237K-CVD as the Best-Calibrated ASCVD Risk Equation Among Three Country-Specific Equations in 9,532 Chinese Adults: A 9-Year Real-World Validation From CHARLS With Decision Curve Analysis.Cardiol Res2026https://conductscience.org/library/papers/42964237PubMed
42,959,645Association between triglyceride high-density cholesterol-glucose body index and 28-day mortality in critically ill patients: a multicenter observational study in China.Ann Intensive Care2026https://conductscience.org/library/papers/42959645PubMed
42,958,482Metabolic score for visceral fat as a predictor of new-onset cardiovascular disease in patients with metabolic syndrome: a validation study in two prospective cohorts (UK Biobank and CHARLS).BMC Cardiovasc Disord2026https://conductscience.org/library/papers/42958482PubMed

1 to 10 of 3,137

See all 3,137 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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