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Paper178902

Construction and analysis of viable deletion mutants of simian virus 40.

Shenk TE and 2 others. J Virol, 1976. Cited by 338 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Construction and analysis of viable deletion mutants of simian virus 40. Papers, record 178902. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/178902

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Construction and analysis of viable deletion mutants of simian virus 40.
PubMed
Journal
J Virol
PubMed
Year
1976
PubMed
Publication types
Comparative Study, Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
338
iCite
Relative citation ratio, by iCite
6.86
iCite
Revised in PubMed
2020-07-24
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Shenk TET E
2Carbon JJ
3Berg PP

Source PubMed

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
DNA, ViralMajor topic
MutationMajor topic
Simian virus 40Major topic
Cell Line
Cell Transformation, Neoplastic
Chromosome Mapping
DNA Restriction Enzymes
Deoxyribonucleases
Endonucleases
Genetic Linkage
Haemophilus
Virus Replication

Source PubMed

References21

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
1165,498Biochemical method for mapping mutational alterations in DNA with S1 nuclease: the location of deletions and temperature-sensitive mutations in simian virus 40.Proc Natl Acad Sci U S A1975https://conductscience.org/library/papers/165498PubMed
2165,505Biochemical procedure for production of small deletions in simian virus 40 DNA.Proc Natl Acad Sci U S A1975https://conductscience.org/library/papers/165505PubMed
3169,100Altered patterns of protein synthesis in infection by SV40 mutants.Cold Spring Harb Symp Quant Biol1975https://conductscience.org/library/papers/169100PubMed
44,288,804Mutants of simian virus 40 differing in plaque size, oncogenicity, and heat sensitivity.J Bacteriol1966https://conductscience.org/library/papers/4288804PubMed
54,291,934Selective extraction of polyoma DNA from infected mouse cell cultures.J Mol Biol1967https://conductscience.org/library/papers/4291934PubMed
64,317,354Topoinhibition and serum requirement of transformed and untransformed cells.Nature1970https://conductscience.org/library/papers/4317354PubMed
74,332,003Specific cleavage of simian virus 40 DNA by restriction endonuclease of Hemophilus influenzae.Proc Natl Acad Sci U S A1971https://conductscience.org/library/papers/4332003PubMed
84,342,968Biochemical method for inserting new genetic information into DNA of Simian Virus 40: circular SV40 DNA molecules containing lambda phage genes and the galactose operon of Escherichia coli.Proc Natl Acad Sci U S A1972https://conductscience.org/library/papers/4342968PubMed
94,343,967Cleavage of Simian virus 40 DNA at a unique site by a bacterial restriction enzyme.Proc Natl Acad Sci U S A1972https://conductscience.org/library/papers/4343967PubMed
104,343,968Cleavage of DNA by R 1 restriction endonuclease generates cohesive ends.Proc Natl Acad Sci U S A1972https://conductscience.org/library/papers/4343968PubMed
114,354,250Detection of two restriction endonuclease activities in Haemophilus parainfluenzae using analytical agarose--ethidium bromide electrophoresis.Biochemistry1973https://conductscience.org/library/papers/4354250PubMed
124,355,833Studies of simian virus 40 DNA. VII. A cleavage map of the SV40 genome.J Mol Biol1973https://conductscience.org/library/papers/4355833PubMed
134,370,797Defective simian virus 40 genomes: isolation and growth of individual clones.Virology1974https://conductscience.org/library/papers/4370797PubMed
144,373,732Viable deletion mutants of simian virus 40: selective isolation by means of a restriction endonuclease from Hemophilus parainfluenzae.Proc Natl Acad Sci U S A1974https://conductscience.org/library/papers/4373732PubMed
154,691,350Purification and further properties of single-strand-specific nuclease from Aspergillus oryzae.Eur J Biochem1973https://conductscience.org/library/papers/4691350PubMed
164,754,844Enzymatic end-to end joining of DNA molecules.J Mol Biol1973https://conductscience.org/library/papers/4754844PubMed
175,063,906The gel electrophoresis of DNA.Biochim Biophys Acta1972https://conductscience.org/library/papers/5063906PubMed
185,231,757A dye-buoyant-density method for the detection and isolation of closed circular duplex DNA: the closed circular DNA in HeLa cells.Proc Natl Acad Sci U S A1967https://conductscience.org/library/papers/5231757PubMed
195,312,500A restriction enzyme from Hemophilus influenzae. I. Purification and general properties.J Mol Biol1970https://conductscience.org/library/papers/5312500PubMed
205,683,998Deoxyribonucleic acid nucleases. II. The effects of metals on the mechanism of action of deoxyribonuclease I.J Biol Chem1968https://conductscience.org/library/papers/5683998PubMed

See all 21 references

Cited by180

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 338 citations.

PMIDTitleJournalYearIn PapersSource
36,916,919Regulation of Virus Replication by BK Polyomavirus Small T Antigen.J Virol2023https://conductscience.org/library/papers/36916919PubMed
33,827,948In Vivo Generation of BK and JC Polyomavirus Defective Viral Genomes in Human Urine Samples Associated with Higher Viral Loads.J Virol2021https://conductscience.org/library/papers/33827948PubMed
30,814,278DNA Tumor Viruses and Their Contributions to Molecular Biology.J Virol2019https://conductscience.org/library/papers/30814278PubMed
25,109,329Thrombospondin-1 repression is mediated via distinct mechanisms in fibroblasts and epithelial cells.Oncogene2015https://conductscience.org/library/papers/25109329PubMed
22,726,243Agnoprotein of mammalian polyomaviruses.Virology2012https://conductscience.org/library/papers/22726243PubMed
21,460,851Upregulation of miR-27a contributes to the malignant transformation of human bronchial epithelial cells induced by SV40 small T antigen.Oncogene2011https://conductscience.org/library/papers/21460851PubMed
18,403,028SV40 reporter viruses.J Virol Methods2008https://conductscience.org/library/papers/18403028PubMed
18,353,419Dephosphorylation of JC virus agnoprotein by protein phosphatase 2A: inhibition by small t antigen.Virology2008https://conductscience.org/library/papers/18353419PubMed
18,022,798Small tumor antigen of polyomaviruses: role in viral life cycle and cell transformation.J Cell Physiol2008https://conductscience.org/library/papers/18022798PubMed
17,715,213Polyomaviruses of birds: etiologic agents of inflammatory diseases in a tumor virus family.J Virol2007https://conductscience.org/library/papers/17715213PubMed
17,620,119Simian virus 40 in humans.Infect Agent Cancer2007https://conductscience.org/library/papers/17620119PubMed
16,299,534Involvement of PP2A in viral and cellular transformation.Oncogene2005https://conductscience.org/library/papers/16299534PubMed
15,890,927Effects of simian virus 40 large and small tumor antigens on mammalian target of rapamycin signaling: small tumor antigen mediates hypophosphorylation of eIF4E-binding protein 1 late in infection.J Virol2005https://conductscience.org/library/papers/15890927PubMed
12,502,843Negative regulation of mitotic promoting factor by the checkpoint kinase chk1 in simian virus 40 lytic infection.J Virol2003https://conductscience.org/library/papers/12502843PubMed
11,884,599Enumeration of the simian virus 40 early region elements necessary for human cell transformation.Mol Cell Biol2002https://conductscience.org/library/papers/11884599PubMed
9,811,697Cell cycle progression in monkey cells expressing simian virus 40 small t antigen from adenovirus vectors.J Virol1998https://conductscience.org/library/papers/9811697PubMed
9,621,096The agnogene of the human polyomavirus BK is expressed.J Virol1998https://conductscience.org/library/papers/9621096PubMed
8,388,518Simian virus 40 small-t antigen binds two zinc ions.J Virol1993https://conductscience.org/library/papers/8388518PubMed
8,388,174SV40 induces mesotheliomas in hamsters.Am J Pathol1993https://conductscience.org/library/papers/8388174PubMed
8,382,310Analysis of simian virus 40 small t antigen-induced progression of rat F111 cells minimally transformed by large T antigen.J Virol1993https://conductscience.org/library/papers/8382310PubMed

See all 180 cited by

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

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  • Genes
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Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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