Paper182157
Selective control of the degradation of normal and aberrant proteins in Reuber H35 hepatoma cells.
Knowles SE and 1 other. Biochem J, 1976. Cited by 246 papers, by iCite.
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ConductScience Library. Selective control of the degradation of normal and aberrant proteins in Reuber H35 hepatoma cells. Papers, record 182157. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/182157
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Selective control of the degradation of normal and aberrant proteins in Reuber H35 hepatoma cells.
- PubMed
Topics17
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Carcinoma, Hepatocellular | Major topic |
| Liver Neoplasms | Major topic |
| Neoplasm Proteins | Major topic |
| Amino Acids | |
| Arginine | |
| Canavanine | |
| Cells, Cultured | |
| Cycloheximide | |
| Fetal Blood | |
| Insulin | |
| Leucine | |
| Leupeptins | |
| Neoplasms, Experimental | |
| Pepstatins | |
| Phenylmethylsulfonyl Fluoride | |
| Phosphoenolpyruvate Carboxykinase (GTP) | |
| Puromycin |
Source PubMed
References25
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 1,089,651 | Degradation of abnormal proteins in Escherichia coli. Formation of protein inclusions in cells exposed to amino acid analogs. | J Biol Chem | 1975 | https://conductscience.org/library/papers/1089651 | PubMed |
| 2 | 13,675,766 | Amino acid metabolism in mammalian cell cultures. | Science | 1959 | https://conductscience.org/library/papers/13675766 | PubMed |
| 3 | 13,862,833 | Cytoplasmic components in hepatic cell lysosomes. | J Cell Biol | 1962 | https://conductscience.org/library/papers/13862833 | PubMed |
| 4 | 13,955,261 | Focal cytoplasmic degradation. | Am J Pathol | 1963 | https://conductscience.org/library/papers/13955261 | PubMed |
| 5 | 14,143,233 | HEPATOMAS IN TISSUE CULTURE COMPARED WITH ADAPTING LIVER IN VIVO. | Natl Cancer Inst Monogr | 1964 | https://conductscience.org/library/papers/14143233 | PubMed |
| 7 | 167,722 | Properties of phosphoenolpyruvate carboxykinase (guanosine triphosphate) synthesized in hepatoma cells in the presence of amino acid analogues. | Biochem J | 1975 | https://conductscience.org/library/papers/167722 | PubMed |
| 8 | 167,723 | Increased degradation rates of protein synthesized in hepatoma cells in the presence of amino acid analogues. | Biochem J | 1975 | https://conductscience.org/library/papers/167723 | PubMed |
| 9 | 4,115,811 | Studies on cellular autophagocytosis. A histochemical study on sequential alterations of mitochondria in the glucagon-induced autophagic vacuoles of rat liver. | Lab Invest | 1972 | https://conductscience.org/library/papers/4115811 | PubMed |
| 10 | 4,151,857 | Comparative studies in vivo and in vitro of rat-liver enzymes. | Eur J Biochem | 1974 | https://conductscience.org/library/papers/4151857 | PubMed |
| 11 | 4,156,834 | The relative stability of liver cytosol enzymes incubated in vitro. | Biochem J | 1974 | https://conductscience.org/library/papers/4156834 | PubMed |
| 12 | 4,243,683 | Biological activities of leupeptins. | J Antibiot (Tokyo) | 1969 | https://conductscience.org/library/papers/4243683 | PubMed |
| 13 | 4,397,029 | A comparison of the proteolytic susceptibility of several rat liver enzymes. | Biochem Biophys Res Commun | 1971 | https://conductscience.org/library/papers/4397029 | PubMed |
| 14 | 4,429,704 | Role of individual cathepsins in lysosomal protein digestion as tested by specific inhibitors. | Biochim Biophys Acta | 1974 | https://conductscience.org/library/papers/4429704 | PubMed |
| 15 | 4,447,628 | Degradation of phosphoenolpyruvate carboxykinase (guanosine triphosphate) in vivo and in vitro. | Biochem J | 1974 | https://conductscience.org/library/papers/4447628 | PubMed |
| 16 | 4,551,144 | Degradation of abnormal proteins in Escherichia coli (protein breakdown-protein structure-mistranslation-amino acid analogs-puromycin). | Proc Natl Acad Sci U S A | 1972 | https://conductscience.org/library/papers/4551144 | PubMed |
| 17 | 4,559,651 | Antipain, a new protease inhibitor isolated from actinomycetes. | J Antibiot (Tokyo) | 1972 | https://conductscience.org/library/papers/4559651 | PubMed |
| 18 | 4,565,695 | Fate of abnormal proteins in E. coli accumulation in intracellular granules before catabolism. | Nat New Biol | 1972 | https://conductscience.org/library/papers/4565695 | PubMed |
| 19 | 4,568,691 | Biological activity of pepstatins, pepstanone A and partial peptides on pepsin, cathepsin D and renin. | J Antibiot (Tokyo) | 1972 | https://conductscience.org/library/papers/4568691 | PubMed |
| 20 | 4,604,628 | Intracellular protein degradation in mammalian and bacterial cells. | Annu Rev Biochem | 1974 | https://conductscience.org/library/papers/4604628 | PubMed |
| 21 | 4,737,734 | Protein degradation in cultured cells. The effect of fresh medium, fluoride, and iodoacetate on the digestion of cellular protein of rat fibroblasts. | J Biol Chem | 1973 | https://conductscience.org/library/papers/4737734 | PubMed |
Cited by62
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 246 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 41,436,460 | Targeting ubiquitination in disease and therapy. | Signal Transduct Target Ther | 2025 | https://conductscience.org/library/papers/41436460 | PubMed |
| 32,527,175 | The discovery and consequences of the central role of the nervous system in the control of protein homeostasis. | J Neurogenet | 2020 | https://conductscience.org/library/papers/32527175 | PubMed |
| 30,867,233 | A Practical Review of Proteasome Pharmacology. | Pharmacol Rev | 2019 | https://conductscience.org/library/papers/30867233 | PubMed |
| 28,845,422 | Integrative metabolomics as emerging tool to study autophagy regulation. | Microb Cell | 2017 | https://conductscience.org/library/papers/28845422 | PubMed |
| 23,908,826 | Intracellular Protein Degradation: From a Vague Idea through the Lysosome and the Ubiquitin-Proteasome System and onto Human Diseases and Drug Targeting. | Rambam Maimonides Med J | 2012 | https://conductscience.org/library/papers/23908826 | PubMed |
| 16,661,588 | Model for Stress-induced Protein Degradation in Lemna minor. | Plant Physiol | 1980 | https://conductscience.org/library/papers/16661588 | PubMed |
| 8,373,357 | Use of 18O-labelled leucine and phenylalanine to measure protein turnover in muscle cell cultures and possible futile cycling during aminoacylation. | Biochem J | 1993 | https://conductscience.org/library/papers/8373357 | PubMed |
| 8,240,260 | Protein catabolism in fibroblasts cultured from patients with mucolipidosis II and other lysosomal disorders. | Biochem J | 1993 | https://conductscience.org/library/papers/8240260 | PubMed |
| 8,040,003 | Immunolocalization of ubiquitin in degenerating insect flight muscle. | Histochem J | 1994 | https://conductscience.org/library/papers/8040003 | PubMed |
| 7,470,043 | Effects of weak bases on the degradation of endogenous and exogenous proteins by rat yolk sacs. | Biochem J | 1980 | https://conductscience.org/library/papers/7470043 | PubMed |
| 7,406,880 | Effects of chymostatin and other proteinase inhibitors on protein breakdown and proteolytic activities in muscle. | Biochem J | 1980 | https://conductscience.org/library/papers/7406880 | PubMed |
| 7,396,824 | A low-molecular-weight inhibitor of the neutral proteinase from rat intestinal smooth muscle. | Biochem J | 1980 | https://conductscience.org/library/papers/7396824 | PubMed |
| 7,378,065 | Distribution and partial purification of a liver membrane protein capable of inactivating cytosol enzymes. | Biochem J | 1980 | https://conductscience.org/library/papers/7378065 | PubMed |
| 7,306,078 | Effects of microbial proteinase inhibitors on the degradation of endogenous and internalized proteins by rat yolk sacs. | Biochem J | 1981 | https://conductscience.org/library/papers/7306078 | PubMed |
| 7,305,902 | Protein degradation during terminal cytodifferentiation. Studies on mammary gland in organ culture. | Biochem J | 1980 | https://conductscience.org/library/papers/7305902 | PubMed |
| 7,236,222 | General characteristics of normal and stress-enhanced protein degradation in Lemna minor (duckweed). | Biochem J | 1980 | https://conductscience.org/library/papers/7236222 | PubMed |
| 7,082,317 | Decreased protein and puromycinyl-peptide degradation in livers of senescent mice. | Biochem J | 1982 | https://conductscience.org/library/papers/7082317 | PubMed |
| 7,044,373 | Degradation of myofibrillar proteins by trypsin-like serine proteinases. | Biochem J | 1982 | https://conductscience.org/library/papers/7044373 | PubMed |
| 7,028,761 | Degradation of proteins microinjected into IMR-90 human diploid fibroblasts. | J Cell Biol | 1981 | https://conductscience.org/library/papers/7028761 | PubMed |
| 6,952,238 | 3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes. | Proc Natl Acad Sci U S A | 1982 | https://conductscience.org/library/papers/6952238 | PubMed |
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- 2026-11-11
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- 2026-09-18
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- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
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- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
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- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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