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Paper · 19615940

Safety and efficacy of sunitinib for metastatic renal-cell carcinoma: an expanded-access trial.

Gore ME and 15 others. Lancet Oncol, 2009. Cited by 487 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Safety and efficacy of sunitinib for metastatic renal-cell carcinoma: an expanded-access trial. Papers, record 19615940. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/19615940

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Safety and efficacy of sunitinib for metastatic renal-cell carcinoma: an expanded-access trial.
PubMed
Journal
Lancet Oncol
PubMed
Year
2009
PubMed
Publication types
Clinical Trial, Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
487
iCite
Relative citation ratio, by iCite
11.7
iCite
Revised in PubMed
2022-03-30
PubMed

Authors16

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Gore MEMartin E
2Szczylik CCezary
3Porta CCamillo
4Bracarda SSergio
5Bjarnason GAGeorg A
6Oudard SStéphane
7Hariharan SSubramanian
8Lee SHSe-Hoon
9Haanen JJohn
10Castellano DDaniel

1 to 10 of 16Source PubMed

See all 16 authors

Topics9

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Antineoplastic AgentsMajor topic
Carcinoma, Renal CellMajor topic
IndolesMajor topic
Kidney NeoplasmsMajor topic
PyrrolesMajor topic
Disease-Free Survival
Humans
Sunitinib
Survival Analysis

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials1

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

TrialTitleThe trial lists it asNamed in the paper's record
NCT00130897Treatment Use Study With Sunitinib (SU011248) For Patients With Cytokine-Refractory Metastatic Renal Cell CarcinomaDerived from the trialYes

Comments and corrections2

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

KindPMIDTitleIn PapersSource
Comment in19,615,941Sunitinib in renal-cell carcinoma: expanded indications.https://conductscience.org/library/papers/19615941PubMed
Comment in19,942,921Targeted therapies: sunitinib in RCC-expanded access equals expanded benefit?https://conductscience.org/library/papers/19942921PubMed

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by215

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 487 citations.

PMIDTitleJournalYearIn PapersSource
41,836,013Epithelial-mesenchymal transition and sunitinib resistance in renal cell carcinoma: mechanisms and therapeutic strategies.Front Pharmacol2026https://conductscience.org/library/papers/41836013PubMed
41,517,566The Evolving Role of Second- and Third-Generation Tyrosine Kinase Inhibitors in Gastrointestinal Malignancies: Advances in Targeted Therapy with Sunitinib, Regorafenib, and Avapritinib.J Clin Med2026https://conductscience.org/library/papers/41517566PubMed
40,944,871Anlotinib in cancer therapy: mechanisms of action, clinical applications, and future perspectives.Cancer Chemother Pharmacol2025https://conductscience.org/library/papers/40944871PubMed
40,698,025The Influence of Safety Performance on Competitive Advantage in the Shipping Industry: A Systematic Literature Review Study.F1000Res2025https://conductscience.org/library/papers/40698025PubMed
40,284,020Synergizing Success: The Role of Anlotinib Combinations in Advanced Non-Small Cell Lung Cancer Treatment.Pharmaceuticals (Basel)2025https://conductscience.org/library/papers/40284020PubMed
39,743,997Effectiveness of systemic treatments for advanced non-clear cell renal cell carcinoma: a systematic review and meta-analysis.Front Oncol2024https://conductscience.org/library/papers/39743997PubMed
39,543,725Transcriptome-based network analysis related to regulatory T cells infiltration identified RCN1 as a potential biomarker for prognosis in clear cell renal cell carcinoma.BioData Min2024https://conductscience.org/library/papers/39543725PubMed
39,250,424Temporary treatment cessation compared with continuation of tyrosine kinase inhibitors for adults with renal cancer: the STAR non-inferiority RCT.Health Technol Assess2024https://conductscience.org/library/papers/39250424PubMed
38,622,715Multi-omics and immunogenomics analysis revealed PFKFB3 as a targetable hallmark and mediates sunitinib resistance in papillary renal cell carcinoma: in silico study with laboratory verification.Eur J Med Res2024https://conductscience.org/library/papers/38622715PubMed
38,618,396Nephrotic Syndrome Due to Sunitinib: A Rare Complication of Treatment of Renal Cell Carcinoma.Cureus2024https://conductscience.org/library/papers/38618396PubMed

1 to 10 of 215

See all 215 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs1

The drugs whose trials, in the Pipelines release, list the paper.

DrugChEMBL IDThe trials list it asTrialsIn Drugs and targets
SUNITINIBCHEMBL535Derived from the trial1https://conductscience.org/library/drugs/CHEMBL535

Source ChEMBL

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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