Paper196178
Covalent phosphorylation in the regulation glycogen synthase activity.
Roach RJ and 1 other. Mol Cell Biochem, 1977. Cited by 82 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
Download JSON
Cite this record
ConductScience Library. Covalent phosphorylation in the regulation glycogen synthase activity. Papers, record 196178. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/196178
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
Topics17
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Glycogen Synthase | Major topic |
| Phosphates | Major topic |
| Amino Acids | |
| Animals | |
| Binding Sites | |
| Cyclic AMP | |
| Epinephrine | |
| Glucagon | |
| Glucosephosphates | |
| Insulin | |
| Kinetics | |
| Models, Biological | |
| Molecular Weight | |
| Organ Specificity | |
| Protein Kinases | |
| Sulfates | |
| Uracil Nucleotides |
Source PubMed
References91
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 168,784 | Insulin and epinephrine effects on heart glycogen synthase and phosphorylase activity. | Am J Physiol | 1975 | https://conductscience.org/library/papers/168784 | PubMed |
| 2 | 16,591,373 | Role of cyclic-3',5'-amp in the response of adipose tissue to insulin. | Proc Natl Acad Sci U S A | 1966 | https://conductscience.org/library/papers/16591373 | PubMed |
| 3 | 5,701,970 | The influence of inorganic phosphate, adenosine triphosphate and glucose 6-phosphate on the activity of liver glycogen synthetase. | Eur J Biochem | 1968 | https://conductscience.org/library/papers/5701970 | PubMed |
| 4 | 4,212,312 | Regulation of rat liver glycogen synthetase D. Role of glucose 6-phosphate and enzyme sulfhydryl groups in activity and glycogen binding. | J Biol Chem | 1974 | https://conductscience.org/library/papers/4212312 | PubMed |
| 5 | 804,488 | Kinetic studies on muscle glycogen synthase. | J Biol Chem | 1975 | https://conductscience.org/library/papers/804488 | PubMed |
| 6 | 14,114,509 | STUDIES ON UDPG-ALPHA-GLUCAN TRANSGLUCOSYLASE. V. TWO FORMS OF THE ENZYME IN DOG SKELETAL MUSCLE AND THEIR INTERCONVERSION. | Biochemistry | 1964 | https://conductscience.org/library/papers/14114509 | PubMed |
| 7 | 5,671,059 | Size and charge isomer separation and estimation of molecular weights of proteins by disc gel electrophoresis. | Arch Biochem Biophys | 1968 | https://conductscience.org/library/papers/5671059 | PubMed |
| 8 | 5,237,897 | An on-off mechanism for liver glycogen synthetase activity. | Proc Natl Acad Sci U S A | 1967 | https://conductscience.org/library/papers/5237897 | PubMed |
| 9 | 4,953,709 | Factors affecting the activity of muscle glycogen synthetase. II. The regulation by Ca++. | J Biol Chem | 1965 | https://conductscience.org/library/papers/4953709 | PubMed |
| 10 | 5,417,408 | On the possibility of metabolite control of liver glycogen synthetase activity. | Biochemistry | 1970 | https://conductscience.org/library/papers/5417408 | PubMed |
| 11 | 4,680,711 | Measurement of molecular weights by electrophoresis on SDS-acrylamide gel. | Methods Enzymol | 1972 | https://conductscience.org/library/papers/4680711 | PubMed |
| 12 | 4,632,914 | Regulation of rat liver glycogen synthetase. Reversible inactivation of glycogen synthetase D by sulfhydryl-disulfide exchange. | J Biol Chem | 1973 | https://conductscience.org/library/papers/4632914 | PubMed |
| 13 | 11,946,166 | Identification of a third form of glycogen synthetase in rat chloroma tumors. | FEBS Lett | 1971 | https://conductscience.org/library/papers/11946166 | PubMed |
| 14 | 818,081 | Rabbit skeletal muscle glycogen synthase. I. Relationship between phosphorylation state and kinetic properties. | J Biol Chem | 1976 | https://conductscience.org/library/papers/818081 | PubMed |
| 15 | 4,350,646 | Hormonal regulation of adipocyte enzymes. The effects of epinephrine and insulin on the control of lipase, phosphorylase kinase, phosphorylase, and glycogen synthase. | J Biol Chem | 1973 | https://conductscience.org/library/papers/4350646 | PubMed |
| 16 | 14,075,096 | STUDIES ON UDPG-ALPHA-GLUCAN TRANSGLUCOSYLASE. III. INTERCONVERSION OF TWO FORMS OF MUSCLE UDPG-ALPHA-GLUCAN TRANSGLUCOSYLASE BY A PHOSPHORYLATION-DEPHOSPHORYLATION REACTION SEQUENCE. | Biochemistry | 1963 | https://conductscience.org/library/papers/14075096 | PubMed |
| 17 | 13,842,294 | Insulin-mediated effect on the activity of UDPG-glycogen transglucosylase of muscle. | Biochim Biophys Acta | 1960 | https://conductscience.org/library/papers/13842294 | PubMed |
| 18 | 4,338,226 | Multiplicity of adenosine 3',5'-monophosphate-dependent protein kinases from rat liver and mode of action of nucleoside 3',5'-monophosphate. | J Biol Chem | 1972 | https://conductscience.org/library/papers/4338226 | PubMed |
| 19 | 13,974,815 | Studies on UDPG-glycogen transglucosylase. I. Preparation and differentiation of two activities of UDPG-glycogen transglucosylase from rat skeletal muscle. | Biochemistry | 1962 | https://conductscience.org/library/papers/13974815 | PubMed |
| 20 | 14,304,886 | KINETICS OF REGULATORY ENZYMES. KINETIC ORDER OF THE YEAST DIPHOSPHOPYRIDINE NUCLEOTIDE ISOCITRATE DEHYDROGENASE REACTION AND A MODEL FOR THE REACTION. | J Biol Chem | 1965 | https://conductscience.org/library/papers/14304886 | PubMed |
Cited by17
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 82 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 38,290,087 | mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b. | J Clin Invest | 2024 | https://conductscience.org/library/papers/38290087 | PubMed |
| 35,835,870 | Molecular basis for the regulation of human glycogen synthase by phosphorylation and glucose-6-phosphate. | Nat Struct Mol Biol | 2022 | https://conductscience.org/library/papers/35835870 | PubMed |
| 32,134,266 | Discovery and Development of Small-Molecule Inhibitors of Glycogen Synthase. | J Med Chem | 2020 | https://conductscience.org/library/papers/32134266 | PubMed |
| 25,527,037 | Expression and purification of functional human glycogen synthase-1:glycogenin-1 complex in insect cells. | Protein Expr Purif | 2015 | https://conductscience.org/library/papers/25527037 | PubMed |
| 23,828,893 | Role of Fas-associated death domain-containing protein (FADD) phosphorylation in regulating glucose homeostasis: from proteomic discovery to physiological validation. | Mol Cell Proteomics | 2013 | https://conductscience.org/library/papers/23828893 | PubMed |
| 22,248,338 | Glycogen and its metabolism: some new developments and old themes. | Biochem J | 2012 | https://conductscience.org/library/papers/22248338 | PubMed |
| 20,538,597 | Genetic depletion of the malin E3 ubiquitin ligase in mice leads to lafora bodies and the accumulation of insoluble laforin. | J Biol Chem | 2010 | https://conductscience.org/library/papers/20538597 | PubMed |
| 18,852,261 | Abnormal metabolism of glycogen phosphate as a cause for Lafora disease. | J Biol Chem | 2008 | https://conductscience.org/library/papers/18852261 | PubMed |
| 16,227,617 | Muscle-specific deletion of the Glut4 glucose transporter alters multiple regulatory steps in glycogen metabolism. | Mol Cell Biol | 2005 | https://conductscience.org/library/papers/16227617 | PubMed |
| 10,491,408 | Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes. | J Clin Invest | 1999 | https://conductscience.org/library/papers/10491408 | PubMed |
| 8,787,686 | Glycogen synthase activity is reduced in cultured skeletal muscle cells of non-insulin-dependent diabetes mellitus subjects. Biochemical and molecular mechanisms. | J Clin Invest | 1996 | https://conductscience.org/library/papers/8787686 | PubMed |
| 8,775,516 | Muscle glycogen resynthesis after short term, high intensity exercise and resistance exercise. | Sports Med | 1996 | https://conductscience.org/library/papers/8775516 | PubMed |
| 6,817,078 | Glycogen synthase in diabetic rat skeletal muscle: activation by insulin. | Mol Cell Biochem | 1982 | https://conductscience.org/library/papers/6817078 | PubMed |
| 6,804,492 | Muscle glucose metabolism following exercise in the rat: increased sensitivity to insulin. | J Clin Invest | 1982 | https://conductscience.org/library/papers/6804492 | PubMed |
| 3,110,217 | Regulation of glycogen synthase and phosphorylase activities by glucose and insulin in human skeletal muscle. | J Clin Invest | 1987 | https://conductscience.org/library/papers/3110217 | PubMed |
| 2,011,684 | Muscle glycogen synthesis before and after exercise. | Sports Med | 1991 | https://conductscience.org/library/papers/2011684 | PubMed |
| 106,236 | Autoantibodies to the insulin receptor activate glycogen synthase in rat adipocytes. | Mol Cell Biochem | 1978 | https://conductscience.org/library/papers/106236 | PubMed |
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
None in this release
- Grants
- Trials
- Comments and corrections
- Genes
- Drugs
- Data
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this paper from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/papers/v1/196178
GET https://conductscience.org/api/papers/v1/196178/references?page=2