Paper198372

Sequential changes in cell-mediated immune responses to herpes simplex virus after recurrent herpetic infection in humans.

Shillitoe EJ and 2 others. Infect Immun, 1977. Cited by 59 papers, by iCite.

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ConductScience Library. Sequential changes in cell-mediated immune responses to herpes simplex virus after recurrent herpetic infection in humans. Papers, record 198372. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/198372

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Sequential changes in cell-mediated immune responses to herpes simplex virus after recurrent herpetic infection in humans.; PubMed
Journal: Infect Immun; PubMed
Year: 1977; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/198372/; PubMed
DOI: https://doi.org/10.1128/iai.18.1.130-137.1977; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC421204/; PubMed
The journal: https://conductscience.org/library/journal-index/0246127; PubMed
Citations, by iCite: 59; iCite
Relative citation ratio, by iCite: 2.02; iCite
Revised in PubMed: 2021-05-26; PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Shillitoe EJ	E J
2	Wilton JM	J M
3	Lehner T	T

Source PubMed

Topics17

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Herpes Labialis	Major topic
Lymphocyte Activation	Major topic
Lymphocytes	Major topic
Macrophage Migration-Inhibitory Factors	Major topic
Adolescent
Adult
Antibodies, Viral
Candida albicans
Chronic Disease
Female
Humans
Lectins
Male
Middle Aged
Simplexvirus
Time Factors
Tuberculin

Source PubMed

Show 11 more topicsShow fewer topics

References29

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	13,872,351	Technique of complementfixation test applicable to the diagnosis of virus diseases.	Mon Bull Minist Health Public Health Lab Serv	1962	https://conductscience.org/library/papers/13872351	PubMed
3	65,753	Cell-mediated immunity to herpes simplex virus types 1 and 2 antigens in leukoplakia and carcinoma in man.	Oncology	1976	https://conductscience.org/library/papers/65753	PubMed
4	191,524	Cell-mediated immune responses in patients with recurrent Herpes Simplex infections. II. Infection-associated deficiency of lymphokine production in patients with recurrent herpes labialis or herpes progenitalis.	J Immunol	1977	https://conductscience.org/library/papers/191524	PubMed
5	4,179,068	Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.	Scand J Clin Lab Invest Suppl	1968	https://conductscience.org/library/papers/4179068	PubMed
6	4,366,917	Production of chemotactic factor and lymphotoxin by human leukocytes stimulated with Herpes simplex virus.	Infect Immun	1974	https://conductscience.org/library/papers/4366917	PubMed
7	4,360,547	Lymphocyte interferon production and transformation after Herpes simplex infections in humans.	J Immunol	1974	https://conductscience.org/library/papers/4360547	PubMed
8	4,315,461	Macrophages and age-dependent resistance to Herpes simplex virus in mice.	J Immunol	1970	https://conductscience.org/library/papers/4315461	PubMed
9	4,119,587	Characterization of a lymphocyte factor which alters macrophage functions.	J Exp Med	1973	https://conductscience.org/library/papers/4119587	PubMed
10	4,110,805	Depression of established delayed hepersensitivity by mumps virus.	J Immunol	1972	https://conductscience.org/library/papers/4110805	PubMed
11	4,179,145	Effect of measles vaccine on immunologic responsiveness.	Pediatrics	1969	https://conductscience.org/library/papers/4179145	PubMed
12	4,359,780	Induction of cellular immunity to herpes simplex virus: relationship to the humoral immune response.	J Immunol	1974	https://conductscience.org/library/papers/4359780	PubMed
13	4,335,071	In vitro stimulation of sensitized lymphocytes by herpes simplex virus and vaccinia virus.	Proc Natl Acad Sci U S A	1972	https://conductscience.org/library/papers/4335071	PubMed
14	4,340,084	Differentiation of type 1 and type 2 herpes simplex virus by in vitro stimulation of immune lymphocytes.	J Immunol	1972	https://conductscience.org/library/papers/4340084	PubMed
15	4,328,483	Latent herpes simplex virus in spinal ganglia of mice.	Science	1971	https://conductscience.org/library/papers/4328483	PubMed
16	4,312,871	A prospective study of chronic herpes simplex virus infection and recurrent herpes labialis in humans.	J Immunol	1970	https://conductscience.org/library/papers/4312871	PubMed
17	4,213,974	Specific IgG and IgM antibody responses in herpes-simplex-virus infections.	J Med Microbiol	1974	https://conductscience.org/library/papers/4213974	PubMed
18	4,217,654	A differential effect of IgM and IgG antibodies on the blastogenic response of lymphocytes to rubella virus.	Cell Immunol	1974	https://conductscience.org/library/papers/4217654	PubMed
19	58,037	Cell-mediated immune response to herpes simplex virus: type-specific lymphoproliferative responses in lymph nodes draining the site of primary infection.	J Immunol	1976	https://conductscience.org/library/papers/58037	PubMed
20	49,654	Immunological basis for latency, recurrences and putative oncogenicity of herpes simplex virus.	Lancet	1975	https://conductscience.org/library/papers/49654	PubMed
21	4,552,465	Cell-mediated immunity in Herpesvirus hominis infections.	Br Med J	1972	https://conductscience.org/library/papers/4552465	PubMed

Show 14 more referencesShow fewer referencesSee all 29 references

Cited by13

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 59 citations.

PMID	Title	Journal	Year	In Papers	Source
7,933,103	Secondary herpes simplex virus latent infection in transplanted ganglia.	J Virol	1994	https://conductscience.org/library/papers/7933103	PubMed
7,251,047	Tolerance and immunity in mice infected with herpes simplex virus: simultaneous induction of protective immunity and tolerance to delayed-type hypersensitivity.	Immunology	1981	https://conductscience.org/library/papers/7251047	PubMed
7,212,769	In vitro studies on the human cellular immune response to commercially available herpes simplex antigens.	Arch Dermatol Res	1980	https://conductscience.org/library/papers/7212769	PubMed
6,295,957	Cell-mediated immunity against herpes simplex virus envelope, capsid, excreted, and crude antigens.	Infect Immun	1983	https://conductscience.org/library/papers/6295957	PubMed
6,289,061	Animal studies on the efficacy of vaccination against recurrent herpes.	Med Microbiol Immunol	1982	https://conductscience.org/library/papers/6289061	PubMed
6,254,886	Immunity to herpes simplex virus type 2: cell-mediated immunity in latently infected guinea pigs.	Infect Immun	1980	https://conductscience.org/library/papers/6254886	PubMed
6,254,875	Lymphocyte-derived chemotactic factor synthesis in initial genital herpesvirus infection: correlation with lymphocyte transformation.	Infect Immun	1980	https://conductscience.org/library/papers/6254875	PubMed
2,993,641	Regulation of herpes simplex virus-specific lymphoproliferation by suppressor cells.	J Virol	1985	https://conductscience.org/library/papers/2993641	PubMed
2,844,457	CD4 and CD8 cell responses to herpes simplex virus in Behçet's disease.	Clin Exp Immunol	1988	https://conductscience.org/library/papers/2844457	PubMed
2,693,335	Recurrent genital tract infection: a result of induced immunosuppression?	Genitourin Med	1989	https://conductscience.org/library/papers/2693335	PubMed
2,553,308	Variation in lymphoproliferative responses during recrudescent orofacial herpes simplex virus infections.	Clin Exp Immunol	1989	https://conductscience.org/library/papers/2553308	PubMed
2,436,840	Immune responses to herpes simplex virus in patients with recurrent herpes labialis: I. Development of cell-mediated cytotoxic responses.	Clin Exp Immunol	1986	https://conductscience.org/library/papers/2436840	PubMed
308,659	Role of T lymphocytes in cellular immune responses during herpes simplex virus infection in humans.	Proc Natl Acad Sci U S A	1978	https://conductscience.org/library/papers/308659	PubMed

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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PMC's ID filePublic domain (US government)
PubMedNLM's terms
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UniProtCC BY 4.0

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