Paper · 20007274

During lytic infections, herpes simplex virus type 1 DNA is in complexes with the properties of unstable nucleosomes.

Lacasse JJ and 1 other. J Virol, 2010. Cited by 58 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. During lytic infections, herpes simplex virus type 1 DNA is in complexes with the properties of unstable nucleosomes. Papers, record 20007274. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/20007274

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: During lytic infections, herpes simplex virus type 1 DNA is in complexes with the properties of unstable nucleosomes.; PubMed
Journal: J Virol; PubMed
Year: 2010; PubMed
Publication types: Journal Article, Research Support, Non-U.S. Gov't; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/20007274/; PubMed
DOI: https://doi.org/10.1128/jvi.01934-09; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC2812404/; PubMed
The journal: https://conductscience.org/library/journal-index/0113724; PubMed
Citations, by iCite: 58; iCite
Relative citation ratio, by iCite: 1.3; iCite
Revised in PubMed: 2021-10-20; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Lacasse JJ	Jonathan J
2	Schang LM	Luis M

Source PubMed

Topics11

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
DNA, Viral	Major topic
Herpesvirus 1, Human	Major topic
Animals
Chlorocebus aethiops
Chromatin
Herpes Simplex
Macromolecular Substances
Models, Molecular
Nucleosomes
Vero Cells
Virus Replication

Source PubMed

Grants1

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by
	Canadian Institutes of Health Research	Canada		PubMed

Source PubMed

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References81

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	18,596,102	Comprehensive characterization of extracellular herpes simplex virus type 1 virions.	J Virol	2008	https://conductscience.org/library/papers/18596102	PubMed
2	15,308,730	Roscovitine inhibits activation of promoters in herpes simplex virus type 1 genomes independently of promoter-specific factors.	J Virol	2004	https://conductscience.org/library/papers/15308730	PubMed
3	17,258,208	Centromeric protein CENP-B proteasomal degradation induced by the viral protein ICP0.	FEBS Lett	2007	https://conductscience.org/library/papers/17258208	PubMed
4	6,257,929	Analysis of herpes simplex virus nucleoprotein complexes extracted from infected cells.	J Virol	1980	https://conductscience.org/library/papers/6257929	PubMed
5	19,535,445	Epigenetic modulation of gene expression from quiescent herpes simplex virus genomes.	J Virol	2009	https://conductscience.org/library/papers/19535445	PubMed
6	19,072,710	Chromatin condensing functions of the linker histone C-terminal domain are mediated by specific amino acid composition and intrinsic protein disorder.	Biochemistry	2009	https://conductscience.org/library/papers/19072710	PubMed
7	15,134	Characterization of components released by alkali disruption of simian virus 40.	J Virol	1977	https://conductscience.org/library/papers/15134	PubMed
8	5,288,261	Compartmentalization of spermine and spermidine in the herpes simplex virion.	Proc Natl Acad Sci U S A	1971	https://conductscience.org/library/papers/5288261	PubMed
9	18,579,611	Linker histones are mobilized during infection with herpes simplex virus type 1.	J Virol	2008	https://conductscience.org/library/papers/18579611	PubMed
10	196,115	Anatomy of herpes simplex virus DNA VIII. Properties of the replicating DNA.	J Virol	1977	https://conductscience.org/library/papers/196115	PubMed

1 to 10 of 81

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Cited by50

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 58 citations.

PMID	Title	Journal	Year	In Papers	Source
42,653,105	Integrated Analysis of Chromatin Accessibility and Transcriptional Dynamics of the Viral Genome Following Pseudorabies Virus Infection.	Int J Mol Sci	2026	https://conductscience.org/library/papers/42653105	PubMed
42,427,522	BAF chromatin remodeling complexes inhibit immediate-early and early, but not late, transcription of herpes simplex virus 1.	bioRxiv	2026	https://conductscience.org/library/papers/42427522	PubMed
41,305,431	Chromatin Regulation of HSV Gene Transcription.	Viruses	2025	https://conductscience.org/library/papers/41305431	PubMed
41,288,450	Equine histones are mobilized within equid alphaherpesvirus 1 (EHV1) replication compartments.	J Virol	2025	https://conductscience.org/library/papers/41288450	PubMed
41,258,712	The H4K20-mono-methyltransferase SETD8 promotes global accessibility of infecting herpes simplex virus genomes.	J Virol	2025	https://conductscience.org/library/papers/41258712	PubMed
40,834,051	Daxx mediated histone H3.3 deposition on HSV-1 DNA restricts genome decompaction and the progression of immediate-early transcription.	PLoS Pathog	2025	https://conductscience.org/library/papers/40834051	PubMed
40,562,219	Epigenetic drugs against human DNA viruses and retroviruses.	Antiviral Res	2025	https://conductscience.org/library/papers/40562219	PubMed
40,537,528	Herpes simplex virus type 1 reshapes host chromatin architecture via transcription machinery hijacking.	Nat Commun	2025	https://conductscience.org/library/papers/40537528	PubMed
39,466,139	The opportunities and challenges of epigenetic approaches to manage herpes simplex infections.	Expert Rev Anti Infect Ther	2024	https://conductscience.org/library/papers/39466139	PubMed
38,451,083	Histone H2A variant H2A.B is enriched in transcriptionally active and replicating HSV-1 lytic chromatin.	J Virol	2024	https://conductscience.org/library/papers/38451083	PubMed

1 to 10 of 50

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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