Paper · 218118
Prostacyclin (PGI2) decreases the cyclic AMP level in coronary arteries.
Schrör K and 1 other. Naunyn Schmiedebergs Arch Pharmacol, 1979. Cited by 31 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Prostacyclin (PGI2) decreases the cyclic AMP level in coronary arteries. Papers, record 218118. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/218118
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
Topics10
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Blood Vessels | Major topic |
| Cyclic AMP | Major topic |
| Epoprostenol | Major topic |
| Prostaglandins | Major topic |
| Adenosine | |
| Animals | |
| Cattle | |
| Coronary Vessels | |
| In Vitro Techniques | |
| Muscle Relaxation |
Source PubMed
Grants0
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None in this release.
Trials0
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None in this release.
Comments and corrections0
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None in this release.
References15
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 4,347,988 | Adenyl cyclase-phosphodiesterase system in arterial smooth muscle. | Life Sci I | 1972 | https://conductscience.org/library/papers/4347988 | PubMed |
| 2 | 366,105 | Prostacyclin: a potent coronary dilating agent in the rat isolated heart [proceedings]. | J Physiol | 1978 | https://conductscience.org/library/papers/366105 | PubMed |
| 3 | 338,313 | Transformation of arachidonic acid and prostaglandin endoperoxides by the guinea pig heart. Formation of RCS and prostacyclin. | Eur J Pharmacol | 1978 | https://conductscience.org/library/papers/338313 | PubMed |
| 4 | 841,106 | Prostacyclin (PGX) is the endogenous metabolite responsible for relaxation of coronary arteries induced by arachindonic acid. | Prostaglandins | 1977 | https://conductscience.org/library/papers/841106 | PubMed |
| 5 | 179,331 | Adenosine relaxation of isolated vascular smooth muscle. | Am J Physiol | 1976 | https://conductscience.org/library/papers/179331 | PubMed |
| 6 | 63,657 | Human arterial and venous tissues generate prostacyclin (prostaglandin x), a potent inhibitor of platelet aggregation. | Lancet | 1977 | https://conductscience.org/library/papers/63657 | PubMed |
| 7 | 339,097 | Prostacyclin is the major prostaglandin released from the isolated perfused rabbit and rat heart. | Nature | 1977 | https://conductscience.org/library/papers/339097 | PubMed |
| 8 | 191,877 | Effects of prostacyclin (PGX) on cyclic AMP concentrations in human platelets. | Prostaglandins | 1977 | https://conductscience.org/library/papers/191877 | PubMed |
| 9 | 4,330,512 | Cyclic AMP and smooth muscle function. | Ann N Y Acad Sci | 1971 | https://conductscience.org/library/papers/4330512 | PubMed |
| 10 | 197,414 | Prostacyclin increases cyclic AMP levels and adenylate cyclase activity in platelets. | Nature | 1977 | https://conductscience.org/library/papers/197414 | PubMed |
1 to 10 of 15
See all 15 referencesCited by6
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 31 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 7,037,509 | Contractile activity and prostacyclin generation in isolated coronary arteries from diabetic dogs. | Diabetologia | 1982 | https://conductscience.org/library/papers/7037509 | PubMed |
| 7,023,464 | Effects of prostacyclin (PGI2) and adenosine (ASN) on total and regional blood flow of isolated, collateralized dog hearts. | Basic Res Cardiol | 1981 | https://conductscience.org/library/papers/7023464 | PubMed |
| 6,268,056 | Possible role of prostaglandins in the regulation of coronary blood flow. | Basic Res Cardiol | 1981 | https://conductscience.org/library/papers/6268056 | PubMed |
| 6,154,247 | Effects of PGI2 and PGI analogues on cAMP levels in cultured endothelial and smooth muscle cells derived from bovine arteries. | Naunyn Schmiedebergs Arch Pharmacol | 1980 | https://conductscience.org/library/papers/6154247 | PubMed |
| 6,095,805 | Uptake and efflux of calcium by canine coronary arteries and the action of adenosine. | Basic Res Cardiol | 1984 | https://conductscience.org/library/papers/6095805 | PubMed |
| 91,976 | PGI2 enhanced cAMP content in bovine coronary arteries in the presence of isobutylmethylxanthine. | Naunyn Schmiedebergs Arch Pharmacol | 1979 | https://conductscience.org/library/papers/91976 | PubMed |
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None in this release.
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- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
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- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
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- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
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- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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