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Paper · 22015496

Complex I and cytochrome c are molecular targets of flavonoids that inhibit hydrogen peroxide production by mitochondria.

Lagoa R and 4 others. Biochim Biophys Acta, 2011. Cited by 137 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Complex I and cytochrome c are molecular targets of flavonoids that inhibit hydrogen peroxide production by mitochondria. Papers, record 22015496. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/22015496

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Complex I and cytochrome c are molecular targets of flavonoids that inhibit hydrogen peroxide production by mitochondria.
PubMed
Journal
Biochim Biophys Acta
PubMed
Year
2011
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
137
iCite
Relative citation ratio, by iCite
4.88
iCite
Revised in PubMed
2024-01-09
PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Lagoa RRicardo
2Graziani IIlaria
3Lopez-Sanchez CCarmen
4Garcia-Martinez VVirginio
5Gutierrez-Merino CCarlos

Source PubMed

Topics22

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Cytochromes cMajor topic
Electron Transport Complex IMajor topic
FlavonoidsMajor topic
Hydrogen PeroxideMajor topic
MitochondriaMajor topic
OxidantsMajor topic
Animals
Antimycin A
Antioxidants
Apigenin
Brain
Catechin
Heart
Kaempferols
Oxidation-Reduction
Oxygen Consumption
Quercetin
Rats
Rats, Wistar
Rotenone
Ubiquinone
Uncoupling Agents

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by74

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 137 citations.

PMIDTitleJournalYearIn PapersSource
42,936,218Flavonoids in cancer pharmacology: molecular mechanisms, tumor microenvironment regulation, and drug resistance.Front Pharmacol2026https://conductscience.org/library/papers/42936218PubMed
42,024,273Protective effects of vitamin E and quercetin against MDMA-induced cardiac and hematological dysfunction in male wistar rats.Pflugers Arch2026https://conductscience.org/library/papers/42024273PubMed
41,155,340Application of Modulators of Ca2+-Activated Big-Conductance Potassium Channels Against Cd2+-Induced Cytotoxicity: A Study on Two Rat Cell Lines, PC12 and AS-30D.Int J Mol Sci2025https://conductscience.org/library/papers/41155340PubMed
40,814,876Neuro-protective Potential of Honey: A Narrative Review.Curr Pharm Des2026https://conductscience.org/library/papers/40814876PubMed
40,722,907Unveiling the Cardioprotective Potential of Hydroxytyrosol: Insights from an Acute Myocardial Infarction Model.Antioxidants (Basel)2025https://conductscience.org/library/papers/40722907PubMed
40,333,596Editorial on the Themed Issue in Honor of Carlos Gutiérrez Merino: Forty Years of Research Excellence in the Field of Membrane Proteins and Bioenergetics.Molecules2025https://conductscience.org/library/papers/40333596PubMed
39,456,436Chemical Composition and Antioxidant Activity of Six Allium Extracts Using Protein-Based Biomimetic Methods.Antioxidants (Basel)2024https://conductscience.org/library/papers/39456436PubMed
39,221,774Nobiletin protects against alcohol-induced mitochondrial dysfunction and liver injury by regulating the hepatic NRF1-TFAM signaling pathway.Redox Rep2024https://conductscience.org/library/papers/39221774PubMed
38,591,201Alleviating Neurodegenerative Diseases Associated with Mitochondrial Defects by Therapeutic Biomolecules.Curr Top Med Chem2024https://conductscience.org/library/papers/38591201PubMed
38,398,528An Update of Kaempferol Protection against Brain Damage Induced by Ischemia-Reperfusion and by 3-Nitropropionic Acid.Molecules2024https://conductscience.org/library/papers/38398528PubMed

1 to 10 of 74

See all 74 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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