Paper · 220377

Thyroid thermogenesis in adult rat hepatocytes in primary monolayer culture: direct action of thyroid hormone in vitro.

Ismail-Beigi F and 2 others. J Gen Physiol, 1979. Cited by 85 papers, by iCite.

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ConductScience Library. Thyroid thermogenesis in adult rat hepatocytes in primary monolayer culture: direct action of thyroid hormone in vitro. Papers, record 220377. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/220377

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Thyroid thermogenesis in adult rat hepatocytes in primary monolayer culture: direct action of thyroid hormone in vitro.; PubMed
Journal: J Gen Physiol; PubMed
Year: 1979; PubMed
Publication types: Journal Article, Research Support, U.S. Gov't, P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/220377/; PubMed
DOI: https://doi.org/10.1085/jgp.73.3.369; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC2215161/; PubMed
The journal: https://conductscience.org/library/journal-index/2985110R; PubMed
Citations, by iCite: 85; iCite
Relative citation ratio, by iCite: 3.1; iCite
Revised in PubMed: 2019-12-10; PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Ismail-Beigi F	F
2	Bissell DM	D M
3	Edelman IS	I S

Source PubMed

Topics11

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Hypothyroidism	Major topic
Liver	Major topic
Oxygen Consumption	Major topic
Triiodothyronine	Major topic
Animals
Cells, Cultured
Dose-Response Relationship, Drug
Glucosephosphate Dehydrogenase
Male
Rats
Sodium-Potassium-Exchanging ATPase

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References29

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	130,385	Thyroid thermogenesis. Relationships between Na+-dependent respiration and Na+ + K+-adenosine triphosphatase activity in rat skeletal muscle.	J Clin Invest	1976	https://conductscience.org/library/papers/130385	PubMed
2	133,119	The effect of thyroid hormone on bile salt-independent bile flow and Na+, K+ -ATPase activity in liver plasma membranes enriched in bile canaliculi.	J Clin Invest	1976	https://conductscience.org/library/papers/133119	PubMed
3	137,242	Dependence of renal (Na+ + k+)-adenosine triphosphatase activity on thyroid status.	J Biol Chem	1976	https://conductscience.org/library/papers/137242	PubMed
4	137,243	Effect of triiodothyronine on the synthesis and degradation of renal cortical (Na+ + k+)-adenosine triphosphatase.	J Biol Chem	1976	https://conductscience.org/library/papers/137243	PubMed
5	138,610	Lack of thyroid hormone effect on activation energy of NaK-ATPase.	Mol Cell Endocrinol	1977	https://conductscience.org/library/papers/138610	PubMed
6	183,268	Thyroid hormones: effect of physiological concentrations on cultured cardiac cells.	Science	1976	https://conductscience.org/library/papers/183268	PubMed
7	190,269	Stimulation of hepatic mitochondrial alpha-glycerophosphate dehydrogenase and malic enzyme by L-triiodothyronine. Characteristics of the response with specific nuclear thyroid hormone binding sites fully saturated.	J Clin Invest	1977	https://conductscience.org/library/papers/190269	PubMed
8	266,704	Regulation of growth hormone messenger RNA by thyroid and glucocorticoid hormones.	Proc Natl Acad Sci U S A	1977	https://conductscience.org/library/papers/266704	PubMed
9	629,333	Glucose metabolism by adult hepatocytes in primary culture and by cell lines from rat liver.	Am J Physiol	1978	https://conductscience.org/library/papers/629333	PubMed
10	894,600	Thyroid calorigenesis in isolated, perfused rat liver: minor role of active sodium-potassium transport.	J Physiol	1977	https://conductscience.org/library/papers/894600	PubMed

1 to 10 of 29

See all 29 references

Cited by10

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 85 citations.

PMID	Title	Journal	Year	In Papers	Source
22,684,107	Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy.	J Clin Invest	2012	https://conductscience.org/library/papers/22684107	PubMed
7,494,538	Response of the rat heart to catecholamines and thyroid hormones.	Mol Cell Biochem	1995	https://conductscience.org/library/papers/7494538	PubMed
7,418,802	Mitogenic effect of the serum of rats exposed to cold.	Experientia	1980	https://conductscience.org/library/papers/7418802	PubMed
6,961,431	Thyroid hormone regulation of heme oxidation in the liver.	Proc Natl Acad Sci U S A	1982	https://conductscience.org/library/papers/6961431	PubMed
6,470,145	Thyroid hormone stimulation of phosphatidylcholine synthesis in cultured fetal rabbit lung.	J Clin Invest	1984	https://conductscience.org/library/papers/6470145	PubMed
6,292,823	Tubular transport processes in proximal tubules of hypothyroid rats. Lack of relationship between thyroidal dependent rise of isotonic fluid reabsorption and Na+ -K+ -ATPase activity.	Pflugers Arch	1982	https://conductscience.org/library/papers/6292823	PubMed
6,123,941	Use of hepatocytes in primary culture for biochemical studies on liver functions.	Mol Cell Biochem	1982	https://conductscience.org/library/papers/6123941	PubMed
6,090,505	Effects of thyroid hormone on sodium pump sites, sodium content, and contractile responses to cardiac glycosides in cultured chick ventricular cells.	J Clin Invest	1984	https://conductscience.org/library/papers/6090505	PubMed
3,039,711	Thyroid hormone and Na,K transport.	Trans Am Clin Climatol Assoc	1987	https://conductscience.org/library/papers/3039711	PubMed
2,538,714	Steady-state physiological variations across a graded series of Na,K-ATPase-amplified cells.	Mol Cell Biol	1989	https://conductscience.org/library/papers/2538714	PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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