Paper · 2294591
Identification of a chromosome 18q gene that is altered in colorectal cancers.
Fearon ER and 9 others. Science, 1990. Cited by 1,769 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
Cite this record
ConductScience Library. Identification of a chromosome 18q gene that is altered in colorectal cancers. Papers, record 2294591. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/2294591
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Publication types
- Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.
- PubMed
Topics23
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Chromosome Deletion | Major topic |
| Chromosomes, Human, Pair 18 | Major topic |
| Colorectal Neoplasms | Major topic |
| DNA, Neoplasm | Major topic |
| Suppression, Genetic | Major topic |
| Alleles | |
| Amino Acid Sequence | |
| Animals | |
| Base Sequence | |
| Blotting, Northern | |
| Blotting, Southern | |
| Cell Adhesion Molecules, Neuronal | |
| Cloning, Molecular | |
| Cross Reactions | |
| DNA Probes | |
| Exons | |
| Gene Expression Regulation, Neoplastic | |
| Humans | |
| Molecular Sequence Data | |
| Polymerase Chain Reaction | |
| RNA, Neoplasm | |
| Sequence Homology, Nucleic Acid | |
| Tumor Cells, Cultured |
Source PubMed
Grants3
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
| Grant, as the record writes it | Agency | Country | NIH project | Stated by | Source |
|---|---|---|---|---|---|
| CA 09243 | NCI NIH HHS | United States | T32CA009243 | PubMed and NIH | NIH RePORTER |
| GM07184 | NIGMS NIH HHS | United States | T32GM007184 | PubMed and NIH | NIH RePORTER |
| GM07309 | NIGMS NIH HHS | United States | PubMed | PubMed |
Trials0
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
None in this release.
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References0
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
None in this release.
Cited by402
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 1,769 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 41,153,383 | Crossroads of Iron Metabolism and Inflammation in Colorectal Carcinogenesis: Molecular Mechanisms and Therapeutic Perspectives. | Genes (Basel) | 2025 | https://conductscience.org/library/papers/41153383 | PubMed |
| 41,093,602 | Clinico-hematopathologic and Genetic Characteristics of Korean Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm: A Retrospective Single-Center Cohort Study. | Ann Lab Med | 2026 | https://conductscience.org/library/papers/41093602 | PubMed |
| 40,821,102 | The role of apoptosis and its potential as a therapeutic target in inflammatory bowel disease associated with colorectal cancer. | Am J Transl Res | 2025 | https://conductscience.org/library/papers/40821102 | PubMed |
| 40,260,608 | Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data. | Mol Oncol | 2025 | https://conductscience.org/library/papers/40260608 | PubMed |
| 39,023,520 | Netrin signaling mediates survival of dormant epithelial ovarian cancer cells. | Elife | 2024 | https://conductscience.org/library/papers/39023520 | PubMed |
| 38,585,553 | Report of a Novel Homozygous Intragenic DCC Duplication and a Review of Literature of Developmental Split-Brain Syndrome aka Horizontal Gaze Palsy with Progressive Scoliosis-2 with Impaired Intellectual Development Syndrome. | Mol Syndromol | 2024 | https://conductscience.org/library/papers/38585553 | PubMed |
| 38,542,469 | Use of Enzymatically Converted Cell-Free DNA (cfDNA) Data for Copy Number Variation-Linked Fragmentation Analysis Allows for Early Colorectal Cancer Detection. | Int J Mol Sci | 2024 | https://conductscience.org/library/papers/38542469 | PubMed |
| 38,458,575 | Netrin-1 as A neural guidance protein in development and reinnervation of the larynx. | Ann Anat | 2024 | https://conductscience.org/library/papers/38458575 | PubMed |
| 38,398,422 | Paroxysmal Dystonic Posturing Mimicking Nocturnal Leg Cramps as a Presenting Sign in an Infant with DCC Mutation, Callosal Agenesis and Mirror Movements. | J Clin Med | 2024 | https://conductscience.org/library/papers/38398422 | PubMed |
| 38,345,070 | TIAM-1 regulates polarized protrusions during dorsal intercalation in the Caenorhabditis elegans embryo through both its GEF and N-terminal domains. | J Cell Sci | 2024 | https://conductscience.org/library/papers/38345070 | PubMed |
1 to 10 of 402
See all 402 cited byGenes1
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes |
|---|---|---|---|
| DCC | 1,630 | Swiss-Prot's references | https://conductscience.org/library/genes/1630 |
Source NCBI Gene
Drugs0
The drugs whose trials, in the Pipelines release, list the paper.
None in this release.
Data7
The data bank entries PubMed's record names. Trial numbers are under Trials.
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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