ConductScience.org, home
Papers
API referenceFor AI assistants

Paper · 2425035

Double isotype production by a neoplastic B cell line. I. Cellular and biochemical characterization of a variant of BCL1 that expresses and secretes both IgM and IgG1.

Chen YW and 5 others. J Exp Med, 1986. Cited by 32 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Download JSON
Cite this record

ConductScience Library. Double isotype production by a neoplastic B cell line. I. Cellular and biochemical characterization of a variant of BCL1 that expresses and secretes both IgM and IgG1. Papers, record 2425035. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/2425035

On this page

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Double isotype production by a neoplastic B cell line. I. Cellular and biochemical characterization of a variant of BCL1 that expresses and secretes both IgM and IgG1.
PubMed
Journal
J Exp Med
PubMed
Year
1986
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
32
iCite
Relative citation ratio, by iCite
0.65
iCite
Revised in PubMed
2019-05-08
PubMed

Authors6

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Chen YWY W
2Word CJC J
3Jones SS
4Uhr JWJ W
5Tucker PWP W
6Vitetta ESE S

Source PubMed

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
B-LymphocytesMajor topic
Immunoglobulin AllotypesMajor topic
Immunoglobulin GMajor topic
Immunoglobulin MMajor topic
LeukemiaMajor topic
Animals
Cell Line
Clone Cells
Electrophoresis, Polyacrylamide Gel
Immunoglobulin Heavy Chains
Immunoglobulin Variable Region
Mice
Phenotype
Precipitin Tests
RNA
Receptors, Antigen, B-Cell

Source PubMed

Grants2

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
AI-11851NIAID NIH HHSUnited StatesP01AI011851PubMed and NIHNIH RePORTER
CA-31534NCI NIH HHSUnited StatesR01CA031534PubMed and NIHNIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References46

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
15,926,297The carriage of immunological memory by small lymphocytes in the rat.J Exp Med1966https://conductscience.org/library/papers/5926297PubMed
2109,513Characterization of the spontaneous murine B cell leukemia (BCL1). III. Evidence for monoclonality by using an anti-idiotype antibody.J Immunol1979https://conductscience.org/library/papers/109513PubMed
34,104,295Cell surface immunoglobulin. II. Isolation and characterization of immunoglobulin from mouse splenic lymphocytes.J Exp Med1971https://conductscience.org/library/papers/4104295PubMed
44,940,896Incidence of cells simultaneously secreting IgM and IgG antibody to sheep erythrocytes.Cell Immunol1971https://conductscience.org/library/papers/4940896PubMed
54,551,216Suppression of immunoglobulin class synthesis in mice. I. Effects of treatment with antibody to -chain.J Exp Med1972https://conductscience.org/library/papers/4551216PubMed
61,055,375Nucleotide sequence of the rightward operator of phage lambda.Proc Natl Acad Sci U S A1975https://conductscience.org/library/papers/1055375PubMed
71,195,397Detection of specific sequences among DNA fragments separated by gel electrophoresis.J Mol Biol1975https://conductscience.org/library/papers/1195397PubMed
8987,581A general method for isolation of high molecular weight DNA from eukaryotes.Nucleic Acids Res1976https://conductscience.org/library/papers/987581PubMed
9313,960Characterization of a spontaneous murine B cell leukemia (BCL1). I. Cell surface expression of IgM, IgD, Ia, and FcR.J Immunol1979https://conductscience.org/library/papers/313960PubMed
10113,776Sequence analysis of cloned cDNA encoding part of an immunoglobulin heavy chain.Nucleic Acids Res1979https://conductscience.org/library/papers/113776PubMed

1 to 10 of 46

See all 46 references

Cited by8

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 32 citations.

PMIDTitleJournalYearIn PapersSource
8,406,582Differentiation of membrane IgE+ rat B cells into IgE-secreting cells.Immunology1993https://conductscience.org/library/papers/8406582PubMed
8,315,375Effect of downregulation of germline transcripts on immunoglobulin A isotype differentiation.J Exp Med1993https://conductscience.org/library/papers/8315375PubMed
8,108,410Switch recombination in normal IgA1+ B lymphocytes.Proc Natl Acad Sci U S A1994https://conductscience.org/library/papers/8108410PubMed
3,127,200Regulation of membrane IgM expression in secretory B cells: translational and post-translational events.EMBO J1987https://conductscience.org/library/papers/3127200PubMed
2,948,185Interleukin 4 mediates autocrine growth of helper T cells after antigenic stimulation.Proc Natl Acad Sci U S A1986https://conductscience.org/library/papers/2948185PubMed
2,785,916Rapid induction of transcription of unrearranged S gamma 1 switch regions in activated murine B cells by interleukin 4.EMBO J1989https://conductscience.org/library/papers/2785916PubMed
2,536,066Clonal and molecular characteristics of the human IgE-committed B cell subset.J Exp Med1989https://conductscience.org/library/papers/2536066PubMed
1,741,377Coexpression of mu and gamma 1 heavy chains can occur by a discontinuous transcription mechanism from the same unrearranged chromosome.Proc Natl Acad Sci U S A1992https://conductscience.org/library/papers/1741377PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/2425035

GET https://conductscience.org/api/papers/v1/2425035/references?page=2

API referenceFor AI assistants