Paper2492500
Lysine catabolism in Streptomyces spp. is primarily through cadaverine: beta-lactam producers also make alpha-aminoadipate.
Madduri K and 2 others. J Bacteriol, 1989. Cited by 52 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
Cite this record
ConductScience Library. Lysine catabolism in Streptomyces spp. is primarily through cadaverine: beta-lactam producers also make alpha-aminoadipate. Papers, record 2492500. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/2492500
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Lysine catabolism in Streptomyces spp. is primarily through cadaverine: beta-lactam producers also make alpha-aminoadipate.
- PubMed
Topics11
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| 2-Aminoadipic Acid | Major topic |
| Amino Acids, Dicarboxylic | Major topic |
| Anti-Bacterial Agents | Major topic |
| Cadaverine | Major topic |
| Diamines | Major topic |
| Lysine | Major topic |
| Streptomyces | Major topic |
| Molecular Structure | |
| Mutation | |
| Species Specificity | |
| beta-Lactams |
Source PubMed
References9
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 5,722,275 | L-Lysine:alpha-ketoglutarate aminotransferase. I. Identification of a product, delta-1-piperideine-6-carboxylic acid. | Biochemistry | 1968 | https://conductscience.org/library/papers/5722275 | PubMed |
| 2 | 5,432,799 | Delta-aminovaleramidase of Pseudomonas putida. | J Biol Chem | 1970 | https://conductscience.org/library/papers/5432799 | PubMed |
| 3 | 4,992,573 | The decarboxylation of L-lysine by Pseudomonas aeruginosa isolates. | J Appl Bacteriol | 1970 | https://conductscience.org/library/papers/4992573 | PubMed |
| 4 | 5,554,291 | Metabolism of basic amino acids in Pseudomonas putida. Catabolism of lysine by cyclic and acyclic intermediates. | J Biol Chem | 1971 | https://conductscience.org/library/papers/5554291 | PubMed |
| 5 | 405,455 | Catabolism of L-lysine by Pseudomonas aeruginosa. | J Gen Microbiol | 1977 | https://conductscience.org/library/papers/405455 | PubMed |
| 6 | 23,086 | Influence of inorganic phosphate and organic buffers on cephalosporin production by Streptomyces clavuligerus. | Arch Microbiol | 1977 | https://conductscience.org/library/papers/23086 | PubMed |
| 7 | 6,772,093 | L-lysine epsilon-aminotransferase involved in cephamycin C synthesis in Streptomyces lactamdurans. | Antimicrob Agents Chemother | 1980 | https://conductscience.org/library/papers/6772093 | PubMed |
| 8 | 6,631,413 | Plasmids, recombination and chromosome mapping in Streptomyces lividans 66. | J Gen Microbiol | 1983 | https://conductscience.org/library/papers/6631413 | PubMed |
| 9 | 3,841,023 | Ammonium repression of cephalosporin production by Streptomyces clavuligerus. | Can J Microbiol | 1985 | https://conductscience.org/library/papers/3841023 | PubMed |
Cited by21
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 52 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 35,353,822 | Engineering of phenylalanine dehydrogenase from Thermoactinomyces intermedius for the production of a novel homoglutamate. | PLoS One | 2022 | https://conductscience.org/library/papers/35353822 | PubMed |
| 28,233,490 | Identification and Characterization of Enzymes Catalyzing Pyrazolopyrimidine Formation in the Biosynthesis of Formycin A. | Org Lett | 2017 | https://conductscience.org/library/papers/28233490 | PubMed |
| 27,793,835 | Biochemical pathways supporting beta-lactam biosynthesis in the springtail Folsomia candida. | Biol Open | 2016 | https://conductscience.org/library/papers/27793835 | PubMed |
| 24,359,569 | Enhancing effect of lysine combined with other compounds on cephamycin C production in Streptomyces clavuligerus. | BMC Microbiol | 2013 | https://conductscience.org/library/papers/24359569 | PubMed |
| 22,622,937 | Lysine cataboism and α-aminoadipate synthesis in Streptomyces clavuligerus. | Appl Microbiol Biotechnol | 1991 | https://conductscience.org/library/papers/22622937 | PubMed |
| 17,573,474 | pcd mutants of Streptomyces clavuligerus still produce cephamycin C. | J Bacteriol | 2007 | https://conductscience.org/library/papers/17573474 | PubMed |
| 16,418,868 | Pipecolic acid in microbes: biosynthetic routes and enzymes. | J Ind Microbiol Biotechnol | 2006 | https://conductscience.org/library/papers/16418868 | PubMed |
| 14,517,363 | Bioprospecting the lat gene in soil samples. | J Biosci | 2003 | https://conductscience.org/library/papers/14517363 | PubMed |
| 11,319,114 | Applications of gene replacement technology to Streptomyces clavuligerus strain development for clavulanic acid production. | Appl Environ Microbiol | 2001 | https://conductscience.org/library/papers/11319114 | PubMed |
| 10,629,179 | Early cephamycin biosynthetic genes are expressed from a polycistronic transcript in Streptomyces clavuligerus. | J Bacteriol | 2000 | https://conductscience.org/library/papers/10629179 | PubMed |
| 10,559,157 | Deletion of the pyc gene blocks clavulanic acid biosynthesis except in glycerol-containing medium: evidence for two different genes in formation of the C3 unit. | J Bacteriol | 1999 | https://conductscience.org/library/papers/10559157 | PubMed |
| 10,197,999 | Inducing effect of diamines on transcription of the cephamycin C genes from the lat and pcbAB promoters in Nocardia lactamdurans. | J Bacteriol | 1999 | https://conductscience.org/library/papers/10197999 | PubMed |
| 9,729,600 | Molecular regulation of beta-lactam biosynthesis in filamentous fungi. | Microbiol Mol Biol Rev | 1998 | https://conductscience.org/library/papers/9729600 | PubMed |
| 9,355,735 | Delta-1-piperideine-6-carboxylate dehydrogenase, a new enzyme that forms alpha-aminoadipate in Streptomyces clavuligerus and other cephamycin C-producing actinomycetes. | Biochem J | 1997 | https://conductscience.org/library/papers/9355735 | PubMed |
| 8,867,627 | Unexpected enhancement of beta-lactam antibiotic formation in Streptomyces clavuligerus by very high concentrations of exogenous lysine. | Appl Microbiol Biotechnol | 1996 | https://conductscience.org/library/papers/8867627 | PubMed |
| 8,579,831 | Effects of enhanced lysine epsilon-aminotransferase activity on cephamycin biosynthesis in Streptomyces clavuligerus. | Appl Microbiol Biotechnol | 1995 | https://conductscience.org/library/papers/8579831 | PubMed |
| 8,031,073 | Catabolism of lysine in Penicillium chrysogenum leads to formation of 2-aminoadipic acid, a precursor of penicillin biosynthesis. | Appl Environ Microbiol | 1994 | https://conductscience.org/library/papers/8031073 | PubMed |
| 1,991,735 | Cloning and location of a gene governing lysine epsilon-aminotransferase, an enzyme initiating beta-lactam biosynthesis in Streptomyces spp. | J Bacteriol | 1991 | https://conductscience.org/library/papers/1991735 | PubMed |
| 1,917,857 | A gene encoding lysine 6-aminotransferase, which forms the beta-lactam precursor alpha-aminoadipic acid, is located in the cluster of cephamycin biosynthetic genes in Nocardia lactamdurans. | J Bacteriol | 1991 | https://conductscience.org/library/papers/1917857 | PubMed |
| 1,917,855 | Localization of the lysine epsilon-aminotransferase (lat) and delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase (pcbAB) genes from Streptomyces clavuligerus and production of lysine epsilon-aminotransferase activity in Escherichia coli. | J Bacteriol | 1991 | https://conductscience.org/library/papers/1917855 | PubMed |
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- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
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- Data
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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