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Paper2492500

Lysine catabolism in Streptomyces spp. is primarily through cadaverine: beta-lactam producers also make alpha-aminoadipate.

Madduri K and 2 others. J Bacteriol, 1989. Cited by 52 papers, by iCite.

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ConductScience Library. Lysine catabolism in Streptomyces spp. is primarily through cadaverine: beta-lactam producers also make alpha-aminoadipate. Papers, record 2492500. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/2492500

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Lysine catabolism in Streptomyces spp. is primarily through cadaverine: beta-lactam producers also make alpha-aminoadipate.
PubMed
Journal
J Bacteriol
PubMed
Year
1989
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
52
iCite
Relative citation ratio, by iCite
2.11
iCite
Revised in PubMed
2019-05-08
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Madduri KK
2Stuttard CC
3Vining LCL C

Source PubMed

Topics11

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
2-Aminoadipic AcidMajor topic
Amino Acids, DicarboxylicMajor topic
Anti-Bacterial AgentsMajor topic
CadaverineMajor topic
DiaminesMajor topic
LysineMajor topic
StreptomycesMajor topic
Molecular Structure
Mutation
Species Specificity
beta-Lactams

Source PubMed

References9

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
15,722,275L-Lysine:alpha-ketoglutarate aminotransferase. I. Identification of a product, delta-1-piperideine-6-carboxylic acid.Biochemistry1968https://conductscience.org/library/papers/5722275PubMed
25,432,799Delta-aminovaleramidase of Pseudomonas putida.J Biol Chem1970https://conductscience.org/library/papers/5432799PubMed
34,992,573The decarboxylation of L-lysine by Pseudomonas aeruginosa isolates.J Appl Bacteriol1970https://conductscience.org/library/papers/4992573PubMed
45,554,291Metabolism of basic amino acids in Pseudomonas putida. Catabolism of lysine by cyclic and acyclic intermediates.J Biol Chem1971https://conductscience.org/library/papers/5554291PubMed
5405,455Catabolism of L-lysine by Pseudomonas aeruginosa.J Gen Microbiol1977https://conductscience.org/library/papers/405455PubMed
623,086Influence of inorganic phosphate and organic buffers on cephalosporin production by Streptomyces clavuligerus.Arch Microbiol1977https://conductscience.org/library/papers/23086PubMed
76,772,093L-lysine epsilon-aminotransferase involved in cephamycin C synthesis in Streptomyces lactamdurans.Antimicrob Agents Chemother1980https://conductscience.org/library/papers/6772093PubMed
86,631,413Plasmids, recombination and chromosome mapping in Streptomyces lividans 66.J Gen Microbiol1983https://conductscience.org/library/papers/6631413PubMed
93,841,023Ammonium repression of cephalosporin production by Streptomyces clavuligerus.Can J Microbiol1985https://conductscience.org/library/papers/3841023PubMed

Cited by21

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 52 citations.

PMIDTitleJournalYearIn PapersSource
35,353,822Engineering of phenylalanine dehydrogenase from Thermoactinomyces intermedius for the production of a novel homoglutamate.PLoS One2022https://conductscience.org/library/papers/35353822PubMed
28,233,490Identification and Characterization of Enzymes Catalyzing Pyrazolopyrimidine Formation in the Biosynthesis of Formycin A.Org Lett2017https://conductscience.org/library/papers/28233490PubMed
27,793,835Biochemical pathways supporting beta-lactam biosynthesis in the springtail Folsomia candida.Biol Open2016https://conductscience.org/library/papers/27793835PubMed
24,359,569Enhancing effect of lysine combined with other compounds on cephamycin C production in Streptomyces clavuligerus.BMC Microbiol2013https://conductscience.org/library/papers/24359569PubMed
22,622,937Lysine cataboism and α-aminoadipate synthesis in Streptomyces clavuligerus.Appl Microbiol Biotechnol1991https://conductscience.org/library/papers/22622937PubMed
17,573,474pcd mutants of Streptomyces clavuligerus still produce cephamycin C.J Bacteriol2007https://conductscience.org/library/papers/17573474PubMed
16,418,868Pipecolic acid in microbes: biosynthetic routes and enzymes.J Ind Microbiol Biotechnol2006https://conductscience.org/library/papers/16418868PubMed
14,517,363Bioprospecting the lat gene in soil samples.J Biosci2003https://conductscience.org/library/papers/14517363PubMed
11,319,114Applications of gene replacement technology to Streptomyces clavuligerus strain development for clavulanic acid production.Appl Environ Microbiol2001https://conductscience.org/library/papers/11319114PubMed
10,629,179Early cephamycin biosynthetic genes are expressed from a polycistronic transcript in Streptomyces clavuligerus.J Bacteriol2000https://conductscience.org/library/papers/10629179PubMed
10,559,157Deletion of the pyc gene blocks clavulanic acid biosynthesis except in glycerol-containing medium: evidence for two different genes in formation of the C3 unit.J Bacteriol1999https://conductscience.org/library/papers/10559157PubMed
10,197,999Inducing effect of diamines on transcription of the cephamycin C genes from the lat and pcbAB promoters in Nocardia lactamdurans.J Bacteriol1999https://conductscience.org/library/papers/10197999PubMed
9,729,600Molecular regulation of beta-lactam biosynthesis in filamentous fungi.Microbiol Mol Biol Rev1998https://conductscience.org/library/papers/9729600PubMed
9,355,735Delta-1-piperideine-6-carboxylate dehydrogenase, a new enzyme that forms alpha-aminoadipate in Streptomyces clavuligerus and other cephamycin C-producing actinomycetes.Biochem J1997https://conductscience.org/library/papers/9355735PubMed
8,867,627Unexpected enhancement of beta-lactam antibiotic formation in Streptomyces clavuligerus by very high concentrations of exogenous lysine.Appl Microbiol Biotechnol1996https://conductscience.org/library/papers/8867627PubMed
8,579,831Effects of enhanced lysine epsilon-aminotransferase activity on cephamycin biosynthesis in Streptomyces clavuligerus.Appl Microbiol Biotechnol1995https://conductscience.org/library/papers/8579831PubMed
8,031,073Catabolism of lysine in Penicillium chrysogenum leads to formation of 2-aminoadipic acid, a precursor of penicillin biosynthesis.Appl Environ Microbiol1994https://conductscience.org/library/papers/8031073PubMed
1,991,735Cloning and location of a gene governing lysine epsilon-aminotransferase, an enzyme initiating beta-lactam biosynthesis in Streptomyces spp.J Bacteriol1991https://conductscience.org/library/papers/1991735PubMed
1,917,857A gene encoding lysine 6-aminotransferase, which forms the beta-lactam precursor alpha-aminoadipic acid, is located in the cluster of cephamycin biosynthetic genes in Nocardia lactamdurans.J Bacteriol1991https://conductscience.org/library/papers/1917857PubMed
1,917,855
Localization of the lysine epsilon-aminotransferase (lat) and delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase (pcbAB) genes from Streptomyces clavuligerus and production of lysine epsilon-aminotransferase activity in Escherichia coli.
J Bacteriol1991https://conductscience.org/library/papers/1917855PubMed

See all 21 cited by

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

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Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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