Paper · 2500252

ZFX has a gene structure similar to ZFY, the putative human sex determinant, and escapes X inactivation.

Schneider-Gädicke A and 4 others. Cell, 1989. Cited by 281 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. ZFX has a gene structure similar to ZFY, the putative human sex determinant, and escapes X inactivation. Papers, record 2500252. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/2500252

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: ZFX has a gene structure similar to ZFY, the putative human sex determinant, and escapes X inactivation.; PubMed
Journal: Cell; PubMed
Year: 1989; PubMed
Publication types: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/2500252/; PubMed
DOI: https://doi.org/10.1016/0092-8674(89)90061-5; PubMed
The journal: https://conductscience.org/library/journal-index/0413066; PubMed
Citations, by iCite: 281; iCite
Relative citation ratio, by iCite: 6.45; iCite
Revised in PubMed: 2022-03-11; PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Schneider-Gädicke A	A
2	Beer-Romero P	P
3	Brown LG	L G
4	Nussbaum R	R
5	Page DC	D C

Source PubMed

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
DNA-Binding Proteins	Major topic
Metalloproteins	Major topic
Sex Determination Analysis	Major topic
X Chromosome	Major topic
Y Chromosome	Major topic
Base Sequence
Blotting, Northern
Cells, Cultured
Cloning, Molecular
Dosage Compensation, Genetic
Gene Expression Regulation
Genes
Humans
Molecular Sequence Data
Multigene Family
Transcription, Genetic

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by83

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 281 citations.

PMID	Title	Journal	Year	In Papers	Source
42,983,080	Transcriptomic convergence and the female protective effect in autism.	Nature	2026	https://conductscience.org/library/papers/42983080	PubMed
42,145,970	Integrative Bioinformatics Analyses Reveal X Chromosome Inactivation Escape Genes Dosage Dysregulation Is the Primary Contributor to Turner Syndrome.	Iran J Biotechnol	2026	https://conductscience.org/library/papers/42145970	PubMed
41,718,873	Molecular Tools for Non-invasive Sexing of Wildlife.	Adv Exp Med Biol	2026	https://conductscience.org/library/papers/41718873	PubMed
41,074,764	De Novo Heterozygous ZFX Frameshift Variant in a Female With an X-Linked Neurodevelopmental Disorder.	Am J Med Genet A	2026	https://conductscience.org/library/papers/41074764	PubMed
40,779,536	Association of germline variants in the ZFX gene with primary hyperparathyroidism.	PLoS One	2025	https://conductscience.org/library/papers/40779536	PubMed
40,670,382	Interpretable deep learning framework for understanding molecular changes in human brains with Alzheimer's disease: implications for microglia activation and sex differences.	NPJ Aging	2025	https://conductscience.org/library/papers/40670382	PubMed
39,896,631	Transcriptomic Convergence and the Female Protective Effect in Autism.	bioRxiv	2025	https://conductscience.org/library/papers/39896631	PubMed
39,048,311	Comparing the roles of sex chromosome-encoded protein homologs in gene regulation.	Genes Dev	2024	https://conductscience.org/library/papers/39048311	PubMed
38,325,380	Variants in ZFX are associated with an X-linked neurodevelopmental disorder with recurrent facial gestalt.	Am J Hum Genet	2024	https://conductscience.org/library/papers/38325380	PubMed
36,550,527	Sex differences in early and term placenta are conserved in adult tissues.	Biol Sex Differ	2022	https://conductscience.org/library/papers/36550527	PubMed

1 to 10 of 83

See all 83 cited by

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
ZFX	7,543	Swiss-Prot's references	https://conductscience.org/library/genes/7543	NCBI Gene
ZFY	7,544	PubTator's text mining	https://conductscience.org/library/genes/7544	NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data1

The data bank entries PubMed's record names. Trial numbers are under Trials.

Data bank	Accession
GENBANK	M26946

Source GENBANK

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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